A starter pack for anyone interested in #autoinflammation and #autoinflammatory diseases. Please let me know if you’d like to be added. go.bsky.app/5M6obrp
Dan Bachovchin
@bachovchin.bsky.social
Scientist at Memorial Sloan Kettering Cancer Center
Got the chance to put together the "Click of Chemical Biologists" starter pack v1 and v2 over the Thanksgiving Break. Feel free to ping me on who else I might be missing! V1: go.bsky.app/3P5i7nJ V2: go.bsky.app/Cr4ej7
Check out our lab's latest paper describing a mutually inhibitory complex between DPP9 and KEAP1 www.jbc.org/article/S002...
The Serine Protease DPP9 and the Redox Sensor KEAP1 Form a Mutually Inhibitory Complex
Synthetic inhibitors of the serine protease DPP9 activate the related NLRP1 and CARD8 inflammasomes and stimulate powerful innate immune responses. Thus, it seems plausible that a biomolecule similarl...
jbc.org