Great to see this study from our colleagues at the HUN-REN BRC out in @natcomms.nature.com 🧬 The paper explores how HLA-II peptide-binding diversity is linked to antibody responses, infection susceptibility and vaccine responses. Congratulations to Máté and all co-authors! doi.org/10.1038/s414...

Máté Manczinger@matemanc.bsky.social · 3w ago

Individuals can carry different variants of HLA genes. Some HLA variants bind a broad range of peptide sequences, whereas others are more selective. Is this variation associated with susceptibility to infection? www.nature.com/articles/s41...

A new @natcomms.nature.com study from the @kintseslab.bsky.social adds an important mechanistic layer to how we think about phages in the gut ecosystem. Congratulations to @aagabor.bsky.social , Tóbiás Sári, Kintses and the whole team.

Kintses Lab@kintseslab.bsky.social · 2mo ago

New paper out in @natcomms.nature.com We usually think of bacteriophages as viruses that interact exclusively with bacteria. Our work suggests the story is more complex: communities.springernature.com/posts/search... We’d love your thoughts! @aagabor.bsky.social #phages #microbiome #virome

Congratulations to @kintseslab.bsky.social group on joining the #REPhRAME project! 🧫 This work at the interface of phage therapy, the #microbiome and #antimicrobial-resistance is an important step toward turning bacteria-targeting viruses into clinically grounded therapeutic strategies.

Kintses Lab@kintseslab.bsky.social · 2mo ago

Can bacteria’s natural enemies help break the cycle of recurrent UTIs? We join #REPhRAME, a €15M @horizoneu.bsky.social clinical project coordinated by #Unimedizin Frankfurt , testing phage therapy + gut microbiome restoration

Congratulations to Eszter Ari @eszterari.bsky.social, researcher in Balázs Papp’s group and group leader at ELTE, on winning the MTA Bolyai Fellowship!🏅

Can harmful gene loss become an evolutionary opportunity? In our new work in @molbioevol.bsky.social , lab-evolved E. coli lines recovering from metabolic gene loss did more than return to normal: some surpassed wild type on nutrients never seen during lab evolution. 📎 doi.org/10.1093/molb...

How can harmful gene loss contribute to evolutionary innovation? Zsuzsa Sarkadi presented new results on this question at the #EMBORulesOfTheGame. Talk title: Growth recovery after gene loss drives mating gains in yeast. @embo.org

Now published! 'Identification of transporter-dependent capsular loci associated with the invasive potential of Escherichia coli' www.nature.com/articles/s41... insights below.....

Thrilled to have presented our work on standardising sequencing metadata with LLMs at the EMBL Symposium AI and Biology in Heidelberg. Huge credit to Norbert Kada, ELTE MSc student, who did the work. #EESAIBio @events.embl.org @balazs-papp-lab.bsky.social

What's the secret to minimizing antibiotic resistance? Our joint work with @csabapallab.bsky.social reveals membrane-targeting antibiotics that simultaneously block another cellular pathway are key. Check out thread below.

Csaba Pal Laboratory@csabapallab.bsky.social · 2y ago

🚨 Our latest research in @naturecomms.bsky.social shows a promising strategy for less resistance-prone #antibiotics. For details, see the thread below and read the paper “Exploring the principles behind antibiotics with limited resistance” here: #MEvoSky www.nature.com/articles/s41...

ESKAPE pathogens are outsmarting us. Our latest paper in @naturemicrobiol.bsky.social reveals alarming ease of resistance evolution to antibiotics in development. Collaborative work with @csabapallab.bsky.social‬ and Kintses Lab

Csaba Pal Laboratory@csabapallab.bsky.social · 2y ago

🚨 Excited to share that our new study, “ESKAPE pathogens rapidly develop resistance against antibiotics in development in vitro” is published in @naturemicrobiol.bsky.social. For details, see the 🧵below and read the paper here: www.nature.com/articles/s41...

Excited to share our joint work with @Csaba_Pal_Lab on the resistance propensity of new antibiotic candidates. Just out in @ScienceTM.

Csaba Pal Laboratory@csabapallab.bsky.social · 2y ago

Thrilled to share our latest work, "Antibiotic candidates for Gram-positive bacterial infections induce multidrug resistance" in Science Translational Medicine! For details, see the thread below and read the paper here: www.science.org/doi/10.1126/...

Thrilled to share our latest work, "Antibiotic candidates for Gram-positive bacterial infections induce multidrug resistance" in Science Translational Medicine! For details, see the thread below and read the paper here: www.science.org/doi/10.1126/...

Antibiotic candidates for Gram-positive bacterial infections induce multidrug resistance

Antibiotic candidates induce multidrug resistance in Staphylococcus aureus without compromising bacterial viability.

science.org

Let me advertise our latest paper and R package: the "mulea", which is dedicated to enrichment analysis, using a resampling based false discovery rate, and applying multiple ontologies (which we collected for many species). t.co/qnSopW2F7M