BatResearch - A.Prof. Aaron Irving
@batresearch.bsky.social
Understanding bats through research. Host-Pathogen responses/Comparative Biology/Immunology. opinions my own. A. Prof @ZJE_institute Zhejiang University
www.nature.com/articles/s41...
ALOX15 orchestrates mitochondrial antiviral immunity and serves as a host target for anti-influenza therapy - Nature Immunology
ALOX15 translocates to mitochondria under RNA virus stress, and orchestrates MAVS innate immunity in a nonenzymatic manner, identifying ALOX15 as a host-directed target for anti-influenza therapy.
nature.com
In case you missed it: Tom Ksiazek joins TWiV to discuss why rapid, accurate diagnosis is a cornerstone of infection control, and how identifying patients early, can make all the difference.
www.nature.com/articles/s41...
ALOX15 orchestrates mitochondrial antiviral immunity and serves as a host target for anti-influenza therapy - Nature Immunology
ALOX15 translocates to mitochondria under RNA virus stress, and orchestrates MAVS innate immunity in a nonenzymatic manner, identifying ALOX15 as a host-directed target for anti-influenza therapy.
nature.com
Bats have often made the cover of journals, though it's rare for a Rhinolophus to make it. #TrendsinMicro www.cell.com/trends/micro...
www.biorxiv.org/content/10.6...
The Vertebrate Genomes Project Phase I: A global reference genome resource
The Vertebrate Genomes Project (VGP) aims to produce complete and near-error-free reference genomes for all ∼70,000 extant vertebrate species. Organized in four phases, it progressively targets all ve...
biorxiv.org
🦇Through our eLearning platform we are pleased to offer new courses, modules and other educational content that can be purchased and completed at any time. From courses to complete beginners through to others tailored for anyone working with bats. More here: www.bats.org.uk/our-work/tra...
eLearning - Training - Bat Conservation Trust
Through our eLearning platform we are pleased to offer new courses, modules and other educational content that can be purchased and completed at any tim...
bats.org.uk
Front Immunol. 2026 May 20:17:1827051. doi: 10.3389/fimmu.2026.1827051. eCollection 2026. Annotation of bat IG H/L/K loci and analysis of the characteristics of bat BCR-CDR3 repertoires. doi.org/10.3389/fimm... #batpapers #IgXs
Frontiers | Annotation of bat IG H/L/K loci and analysis of the characteristics of bat BCR-CDR3 repertoires
Bats represent the second largest order of mammals and are the only flying mammals, exhibiting remarkable biological characteristics such as viral tolerance,...
doi.org
Mol Ecol. 2026 Jun;35(11):e70415. doi: 10.1111/mec.70415. Unravelling Extended Longevity Mechanism in Bats: Insights From Life-History Traits and Comparative Genomics. doi.org/10.1111/mec.... #batpapers #longevity
Unravelling Extended Longevity Mechanism in Bats: Insights From Life‐History Traits and Comparative Genomics
Chiroptera species (hereafter bats) exhibit extraordinarily long lifespans compared to non-flying mammals of similar body size, yet the underlying ecological drivers and molecular mechanisms remain p...
doi.org
J Virol. 2026 Jun 10:e0035226. doi: 10.1128/jvi.00352-26. Online ahead of print. Genetic diversity of pangolin coronaviruses reveals a key immuno-evasive substitution at spike residue 519. doi.org/10.1128/jvi.... #batpapers #pangolinpapers #SARSrCoV
Genetic diversity of pangolin coronaviruses reveals a key immuno-evasive substitution at spike residue 519 | Journal of Virology
Pangolins are frequently moved through illegal wildlife trade, creating opportunities for animal viruses to cross borders and encounter people. Guangdong pangolin coronaviruses are genetically close t...
doi.org
In case you've ever wondered about the gaokao, China's university entrance exam... mp.weixin.qq.com/s/KxRpLNe-Uq...
The Gaokao: Two Days That Stop China 高考2026：1290万人走进考场的两天
全国考试 12.9M candidates 升学关键 Two-day event 家庭关注 National attention 校园冲刺 Final-year pressure 名校目标 985 · 211 · DFC 国际视角 Why it matters
mp.weixin.qq.com
yes, by INRB. www.facebook.com/615597070048... It seems the strain announced by Institut National de Santé Publique RDC is Bundibugyo virus, which is less comon than others
38 reactions · 4 comments | Institut National de Santé Publique RDC on Reels
facebook.com
Last day at the #RapidEvolution of immunity conference held with @cnrsbiologie.bsky.social Biology researchstation in Roscoff, France
virological.org/t/complete-s...
Complete sequence of Orthohantavirus andesense virus: Swiss resident 2026
Posted on behalf of the Swiss National Reference Center for Emerging Viral Infections, Geneva University Hospitals and the Institute of Medical Virology, University of Zurich (Partner Laboratory Natio...
virological.org
Virological characteristics of SARS-CoV-2-related coronaviruses dynamically circulating in Southeast Asia: Cell www.cell.com/cell/fulltex...
Virological characteristics of SARS-CoV-2-related coronaviruses dynamically circulating in Southeast Asia
A study by the G2P-Asia consortium provides a comprehensive analysis spanning fieldwork, as well as experimental and computational investigations into the biology, evolution, and ecology of novel SARS...
cell.com
🦇🌎🧪🦊White-nose syndrome is in Alberta (but not everywhere) and British Columbia is still largely unaffected. Be aware. Use decontamination protocols to reduce any chances of spreading the disease. #Cavers #BuildingManagers #Biologists especially.
Detection of a Merbecovirus with potential ACE2 usage in France. Emerg Microbes Infect. 2026 Dec;15(1):2651469. doi.org/10.1080/2222... #batvirus #MERS
Detection of a Merbecovirus with potential ACE2 usage in France
A novel Merbecovirus, designated Cam-2023, has been identified in Pipistrellus pipistrellus in France through non-invasive surveillance. Phylogenetic analysis demonstrates that Cam-2023 belongs to ...
doi.org
Molecular survey of Borrelia spp. in bats and soft tick infesting bats in Thailand. Curr Res Parasitol Vector Borne Dis . 2026 Apr 7:9:100374 doi.org/10.1016/j.cr...
Redirecting
doi.org
Using Serosurveys to Optimize Surveillance for Zoonotic Pathogens. Ecohealth. 2026 Apr 25. doi.org/10.1007/s103... #batpapers #batserology
Using Serosurveys to Optimize Surveillance for Zoonotic Pathogens - EcoHealth
Zoonotic pathogens pose significant risk to human health, with spillover into human populations contributing to chronic disease and epidemics. Despite the widely recognized burden of zoonotic spillover, our ability to identify which animal populations serve as primary reservoirs remains incomplete. This challenge is compounded when prevalence in reservoir populations reaches detectable levels only at specific times of year. In these cases, statistical models designed to predict the timing of peak prevalence could guide field sampling for active infections or predict when spillover risk is likely to be greatest. Thus, we develop a general mathematical model that leverages routinely collected serosurveillance data to optimize sampling for elusive pathogens. Using simulated data, we show that our methodology reliably identifies times when pathogen prevalence is expected to peak. Then, we demonstrate an implementation of our method using previously published surveillance data in straw-colored fruit bats (Eidolon helvum). The generality and simplicity of our methodology make it broadly applicable to a wide range of putative reservoir species where seasonal patterns of birth lead to cyclic, but potentially short-lived, pulses of pathogen prevalence.
doi.org
Ecological Factors and Host Community Characteristics as Potential Drivers of Bat RNA Virus Spillover. Biology (Basel) . 2026 Apr 12;15(8):609. doi.org/10.3390/biol... #batpapers #batviruses
doi.org
In vitro characterization of different genetic strains of rabies virus isolated from non hematophagous bats. Res Vet Sci . 2026 Apr 20:207:106204. doi.org/10.1016/j.rv... #batpapers
Redirecting
doi.org
The ornamental trade in painted woolly bats (Kerivoula picta) in Ho Chi Minh City, Vietnam: Global Ecology and Conservation 66 (2026) e04098 doi.org/10.1016/j.ge... #batpapers
Redirecting
doi.org
SARS-CoV-2 Nsp15 facilitates immune evasion and viral replication by limiting multiple host innate immune pathways, including cGAS–STING www.microbiologyresearch.org/content/jour...
SARS-CoV-2 Nsp15 facilitates immune evasion and viral replication by limiting multiple host innate immune pathways, including cGAS–STING
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nonstructural protein 15 (Nsp15) is a conserved uridine-specific endoribonuclease (EndoU) and is implicated in innate immune evasion, yet i...
microbiologyresearch.org
Lessons learned from bat and rodent reservoir hosts of zoonotic viruses - ScienceDirect www.sciencedirect.com/science/arti...
Lessons learned from bat and rodent reservoir hosts of zoonotic viruses
Zoonotic virus emergence is a continued threat to global health, though more than two-thirds originate in wildlife. Within natural reservoirs, bats an…
sciencedirect.com
I'm sorry, 50 what now? "We present a GPU implementation of kallisto for RNA-seq transcript quantification (...). For a large dataset of 295 million reads, runtime drops from 40 minutes to 50 seconds" www.biorxiv.org/content/10.6...
I decided to upload all my (semi)science videos to here.. You'll slowly get a bunch of random ones. This is #Wuhan #China (nov 2025) #modernvirology...