Andy Baxevanis

@baxevanislab.bsky.social

Exploring hydrozoan genomes that might tell us a thing or two about ourselves. Posts are my own.

📢 We've just published a chromosome-level nuclear and mitochondrial genome assembly for Capitella teleta (~243.6 Mb). Despite a highly conserved gene family repertoire, both genomes show extensive rearrangements, revealing a decoupling of gene family and chromosomal evolution.

🧬 New genome alert! We’ve generated a chromosome-level assembly for the hydrozoan Podocoryna. With both polyp and free-swimming medusa stages, Podocoryna is a powerful model for exploring the evolution of complex traits in early animal lineages.

A long overdue reckoning for Henrietta Lacks — the Black woman whose cancer cells led to breakthroughs but were harvested without her consent. Novartis has settled a lawsuit by Lacks’ estate that alleged the pharmaceutical giant profited off her cells. https://bit.ly/3NgCeBs

Henrietta Lacks' Family Reaches Settlement in Fight Over Her Stolen Cells

Details of the Novartis agreement aren't public, but the family says it is pleased with the outcome.

capitalbnews.org

I’m recruiting new members to the Farrell Lab this summer. We will have space for 1 postdoc (since Abhinav is leaving to start his own lab at U Arizona!!) and 2 postbacs, since my current two will leave for PhD programs at the end of the summer. More details in thread:

The re-analysis of this #sponge #ctenophore study made me realize how important it is to really *look* at your data. Their filtering pipeline was meant to retain "strong" genes, but many of them had NO ctenophores and most had polyphyletic sponges. Time to put down the pitchforks for a while.

Casey Dunn@caseywdunn.bsky.social · 7mo ago

Our eLetter github.com/caseywdunn/s... responding to a recent Science paper was just posted. The paper found more genes with consistent support for sponge-sister than ctenophore-sister. We found several technical issues that, when corrected, reverse the conclusions and recover ctenophore-sister.

A Newsweek article on Turritopsis, featuring insights and commentary from Mike Layden, Christy Schnitzler, and Maria Pia Miglietta, explaining the importance of studying cnidarian species to advance our knowledge of regeneration and stem cell biology. A nice read! www.newsweek.com/the-immortal...

The 'immortal' animal that can cheat death

One ocean-dwelling creature found in many tropic waters is known to be able to reserve its own life cycle, cheating death.

newsweek.com

A new Hydractinia single-cell atlas from the Schnitzler lab: >47K cells from feeding polyps and stolon tissue that refines major somatic cell lineages and recovers a novel population of putative immune cells – a valuable resource for the cnidarian research community and beyond! tinyurl.com/hsymSC

An updated and spatially validated somatic single-cell atlas of Hydractinia symbiolongicarpus - BMC Genomics

Single-cell RNA sequencing (scRNA-seq) has revolutionized transcriptomic research, enabling the creation of detailed tissue, organ, and species-level atlases for model organisms. In Hydractinia, a cni...

tinyurl.com