Zebrafish Rock!

@zebrafishrock.bsky.social

Award-winning home tank for all things #zebrafish! Connect with us at https://linktr.ee/zebrafishrock 🐟🎸

In a new (ish) preprint, we used CRISPR barcodes to label germline stem cell clones in zebrafish, then tracked their contributions to sperm production for 2 years. Instead of staying stable, individual clones rose, fell, and disappeared over time. www.biorxiv.org/content/10.6...

Clonal dynamics deviate from neutral drift in zebrafish spermatogenesis

Spermatogonial stem cells (SSCs) maintain male fertility, but how their clonal dynamics change with age remains poorly understood. Here, we use in vivo CRISPR barcoding in zebrafish to label SSCs and ...

biorxiv.org

“These findings support the implementation of environmental monitoring [e.g. sludge] as a practical & cost-effective alternative to sentinel-based surveillance, improving pathogen detection while reducing animal use in accordance w/ the 3Rs principles & Directive 2010/63/EU.” New from Checco et al.

bioRxivpreprint@biorxivpreprint.bsky.social · 5d ago

Environmental monitoring for pathogen detection in zebrafish housing systems using molecular techniques: A 3Rs principles-based approach https://www.biorxiv.org/content/10.64898/2026.07.29.741654v1