Excited to share that the UCSF Collins Lab will be presenting at #ORS2026 this week in Charlotte! If you’re interested in learning about spatial transcriptomics, fat–joint crosstalk, or aging-associated #osteoarthritis, we would love to connect - reach out or stop by! 💫 #science #ortho #fatchat

Excited to share the Collins Lab Lineup for #ORS2026 🎉 From spatial transcriptomics to fat-joint crosstalk in #osteoarthritis, our team is presenting talks & posters all weekend long 🎤 Stop by my NIRA poster & podium on Sunday morniny to learn more about the role of fat in OA & #aging 🧬

Attending #ORS2026? Visit the Future Faculty Poster Session to meet an exceptional lineup of up-and-coming leaders in orthopaedic research! We are thrilled to highlight candidates Mareeswari Paramasivan & Luke Mattar! Sun, March 29th | 10:15–11:15 AM | Exhibit Hall @orssociety.bsky.social #ORSSMC

Attending #ORS2026? Looking to hire a senior post-doc, resident, or fellow for their first independent faculty position? Stop by at the Future Faculty Poster Session and meet ~22 extraordinary faculty candidates! Sunday, March 29th | 10:15-11:15 am | Exhibit Hall @orssociety.bsky.social #ORSSMC

Going to #ORS2026 in Charlotte, NC? Check out this awesome Spotlight Speaker! Stefaan Verbruggen, PhD (@docbruggsbunny.bsky.social) “Predictive in vitro and in silico Modeling of Mechanical Microenvironments” Sun, 3/29 | 9:45-10:15 AM | Ballroom CD lnkd.in/gqhEX_ZZ #ORSSMC @orssociety.bsky.social

Exciting new study on the role of PIEZOs in Chondrocytes! Relevance to arthritis and pain. From: @farsh-g.bsky.social & @kelseyhcollins.bsky.social arthritis-research.biomedcentral.com/articles/10....

Chondrocyte-specific knockout of Piezo1 and Piezo2 protects against post-traumatic osteoarthritis structural damage and pain in mice - Arthritis Research & Therapy

Background Osteoarthritis (OA) is a debilitating joint disease characterized by cartilage degeneration, synovial inflammation, and bone remodeling, with limited therapeutic options targeting the under...

arthritis-research.biomedcentral.com

Congratulations Priscilla Tjandra and all on our new paper: tinyurl.com/2mbhxuz7. We demonstrate a role for complement factor D secreted by fat in the early and persistent pain after knee injury. Thanks to Darren Dunlao and Jacob @ucsfmicrobiome.bsky.social for collab on eicosanoid profiling!

New in @JOrthopRes.bsky.social: Mechanical behavior of 5.5 mm CoCr & Ti spinal rods varies significantly among suppliers, up to 29% difference in yield load, suggesting rods are not mechanically equivalent. Key considerations for surgical planning! buff.ly/RovQOAJ #ORSSMC @ORSsociety.bsky.social

💡 Inspire the next generation! 🌟 “Getting kids excited about orthopaedics at ORS Open Door reminded me why I love this field.” – Lindsey Lammlin, PhD (@zlammlin.bsky.social) Apply for the Early Career Travel Award today! ors.org/outreach-trave… Deadline is Aug 25! #ORSOpenDoor2026 #STEMoutreach 🔬

New in @JOrthopRes.bsky.social: Cartilage oligomeric matrix protein (COMP) levels in synovial fluid—higher in males—show strong potential to distinguish OA from RA with high sensitivity and specificity. A promising step toward better diagnostics! buff.ly/phMqkZ8 #ORSSMC @ORSsociety.bsky.social

Can dog ACL injuries help humans? 🐶 A cross-species study in @JOrthopRes.bsky.social reveals shared synovial fluid proteins linked to post-traumatic OA. Periostin stands out as a potential biomarker & therapeutic target for joint injury. buff.ly/ODWeaI6 #ORSSMC @ORSsociety.bsky.social

The Postbac Education Support Fund will reopen for applications on June 2nd (propelscholars.org/partners/pos...). Thanks to @solvingforsci.bsky.social for their support! (Deadline June 30th)

New in @JOrthopRes.bsky.social: Electrochemical testing of CoCrMo in osteoarthritic synovial fluid from 118 TKA patients shows variability, suggesting implant performance may depend on the patient’s local physiological environment & SF composition. buff.ly/ej90Bxf #ORSSMC @ORSsociety.bsky.social

Did you know that Hartley guinea pigs spontaneously develop osteoarthritis (OA), alike humans? Check out Dr. Afzali's paper in @jorthopres.bsky.social utilizing this model system to validate the intravenous delivery of cellular therapies. Link: buff.ly/evclxZd #ORSSMC #ORSxDerby

Recent findings in @JOrthopRes.bsky.social show loss of effective lubricating viscosity is the primary mechanical marker of synovial inflammation in equine OA, linked to inflammation biochemical markers like white blood cell count & PGE2. buff.ly/gwOPVsK #ORSxDerby #ORSSMC @ORSsociety.bsky.social

Join us for our quarterly C-COMP journal club, featuring this exciting new paper by the team of @kelseyhcollins.bsky.social and @farsh-g.bsky.social Monday May 12th 10 am CST- ask us how to register! www.science.org/doi/full/10....

Adipose-derived leptin and complement factor D mediate osteoarthritis severity and pain

Osteoarthritis and knee joint pain are driven by systemic leptin and complement factor D secreted by adipose tissue.

science.org

Tomorrow is the Kentucky Derby! In parallel, the #ORSSMC will be posting articles from @jorthopres.bsky.social showcasing how @orssociety.bsky.social members contribute to the success and longevity of animal and human athletes alike. #ORSxDerby #KyDerby #OneHealth 🏇 🏃‍♀️ Link: buff.ly/raqOTGd

I am so heartened to this seriously AWESOME #SaveNSF website go up today!!!! Has a take action toolkit with: 1. Press outreach templates 2. Social media toolkit 3. Elected official outreach 4. Talking points Check it out and share widely!!!! Likely more to come. www.savensf.com

Your regular reminder that NSF grants built the internet and helped the U.S. dominate tech.

Dan Garisto@dangaristo.bsky.social · last yr.

BREAKING: NSF has frozen all grant funding, as of yesterday. It's unclear when they will resume funding awards, or why the pause has been put in place. www.nature.com/articles/d41...

Lateral epicondylitis, or 'tennis elbow', impacts women more often than men. Kazuhiro Ikeda & coauthors looked at potential causes for this discrepancy, finding sex differences in wrist torque and endurance: onlinelibrary.wiley.com/doi/10.1002/... #ORSxDerby #ORSSMC @jorthopres.bsky.social

This study used caliberated CT to show that bone density changes across the innominate bone due to age and sex tend to vary between individuals, although consistent effects were seen at specific regions. buff.ly/j2Uhe4J @orssociety.bsky.social #ORSSMC #ORSxDerby #KyDerby #BMD #fracture

Patients w/ Ehlers-Danlos Syndrome (cEDS) present w/ extensible skin & joint instability, with more females affected. In a mouse model of cEDS, Vet-Scientist Dr. Jaclyn Carlson discovered altered healing in this population. Link: buff.ly/crnkIwN #ORSSMC #ORSxDerby

Like us, horses can injure their tendons and ligaments & often don't recover full tendon or ligament strength. Diane Little, et al. explore preclinical tendon & ligament animal models for developing better treatment: onlinelibrary.wiley.com/doi/10.1002/... #ORSxDerby #ORSSMC @jorthopres.bsky.social

In @JOrthopRes.bsky.social, the Christiansen Lab (UC Davis) reports sex differences in mice post-femur fracture: 🦴 Males show greater systemic bone loss & TNF-α elevation 💪 Females trend toward greater muscle loss in the injured limb buff.ly/LfFQjGn #ORSxDerby #ORSSMC @ORSsociety.bsky.social

Meet Dr. Brenna Pugliese, Veterinarian and PhD candidate in the Schnabel Lab at @ncstate.bsky.social . Dr. Pugliese investigates intra-articular therapies for equine patients, with applications toward human health. Spotlight: buff.ly/1dDyb4O #ORSSMC #ORSxDerby

I am honored to highlight Vet-Scientist and past @orssociety.bsky.social president, Dr. Kurt Hankenson! The Hankenson Lab @umich.edu is interested in elucidating mechanisms of bone formation to improve clinical care. Spotlight: buff.ly/I8OoHC0 #ORSSMC #ORSxDerby

Vet-scientists in the @orssociety.bsky.social improve orthopaedic health for animals & humans. Meet Dr. Kelly Santangelo: buff.ly/K1go4OO The Santangelo Lab aims to enhance healthspan by aiding functional, independent, & pain-free mobility. #ORSSMC #ORSxDerby

Great interview with Prof. Mandi Lopez, Professor of Veterinary Surgery in LSU School of Veterinary Medicine ! She shares her career, interests, and life advice for the orthopaedic research community! Check it out here: buff.ly/I8VdeCt @orssociety.bsky.social #ORSSMC #ORSxDerby #KyDerby

LinkedIn

This link will take you to a page that’s not on LinkedIn

lnkd.in

In honor of the Kentucky Derby this week, the #ORSSMC is excited to highlight some of the stellar Veterinary Scientists in the @orssociety.bsky.social & their research in the areas of #sexdifferences, #animalhealth, and #onehealth. Stay tuned on May 1, 2, & 3 for more! #ORSxDerby #KyDerby

Meet Dr. Dianne Little, DVM, PhD, a vet surgeon & orthopaedic scientist leveraging multi-omics to advance rotator cuff tendon tissue engineering. Her translational work advocates for more inclusive approaches in regenerative medicine. 👩‍🔬 buff.ly/3mrzXoF #ORSxDerby #ORSSMC @ORSsociety.bsky.social