A model of how beta and gamma rhythms impact synaptic integration in pyramidal neurons. Spatially targeted inhibitory rhythms differentially affect neuronal integration doi.org/10.7554/eLif... #neuroscience

Spatially targeted inhibitory rhythms differentially affect neuronal integration

Beta and gamma inhibitory rhythms are preferentially tuned to govern synaptic integration in layer 5 pyramidal neurons by differentially modulating responses to inputs targeting distal dendritic and p...

doi.org

Kundu lab at university of missouri is also seeking research assistants for iEEG memory data analysis $46K with benefits. MATLAB required #neurojobs #workingmemory #ieeg - apply erecruit.umsystem.edu/psp/tamext/C...

Kundu lab at Univ of Missouri is hiring a lab manager/staff scientist! Come study memory in human patients using iEEG data in a chill college town. MATLAB required. $52K-$80K neurojobs.sfn.org/job/39531/le... #academicjobs #researchspecialist #signalprocessing #neuroscience #iEEG #neurojobs

Kundu lab at Univ of Missouri is hiring a highly motivated lab manager/staff scientist! Come study memory in human patients using iEEG data in a chill college town. MATLAB required. $52K-$80K neurojobs.sfn.org/job/39531/le... #academicjobs #researchspecialist #signalprocessing #neuroscience #iEEG

Whew! Okay im good :)

Michael Okun@michaelokun.bsky.social · 7mo ago

This is one of the most rigorous long-term prospective looks at coffee, tea and cognitive outcomes. The signal is consistent across dementia diagnosis, subjective complaints and telephone based cognitive testing. The pattern matters. Moderate intake = sweet spot. More is not necessarily better.

Block that acetylcholine and just doesn't feel worth it any more... Cholinergic modulation of dopamine release drives effortful behaviour www.nature.com/articles/s41...

Cholinergic modulation of dopamine release drives effortful behaviour - Nature

In the nucleus accumbens, acetylcholine boosts dopamine release to promote effortful behaviour.

nature.com

Should we rethink how risky deep brain stimulation (DBS) really is? What does reframing mean? Lucas Philipp and colleagues describe in a new paper in Annals of Neurology whether the risks of DBS should be viewed differently when compared to other common elective surgeries.

Parkinson’s disease affects everyone differently and changes over time. This free book answers some of the most frequently asked questions about Parkinson’s: Parkinson.org/library/books/faq

Frequently Asked Questions: A Guide to Parkinson’s Disease

This book answers some of the most frequently asked questions about Parkinson’s disease (PD).

parkinson.org

Bursting gamma and beta dynamics underlie working memory. Working memory is a rhythmic dance, as is cortex. doi.org/10.1016/j.ne... #neuroscience

Excited to share my first publication as a PI! Beta and gamma bursting in frontal and temporal areas predict working memory performance in humans. #WorkingMemory #Neuroscience doi.org/10.1016/j.ne...

Beta bursts are brief, structured events that may act as transient “computational primitives” the brain uses to flexibly coordinate processing across regions. doi.org/10.1177/1073... #neuroscience

Beta Burst Waveform Diversity: A Window onto Cortical Computation - Holly Rayson, Quentin Moreau, Solene Gailhard, Maciej J. Szul, James J. Bonaiuto, 2025

Neural activity in the beta band is increasingly recognized to occur not as sustained oscillations but as transient burst-like events. These beta bursts are div...

doi.org

Fantastic sfn talk by Earl Miller covering the latest on gamma, beta, and how large scale networks may coordinate cortical modules for cognition

Earl K. Miller@earlkmiller.bsky.social · 8mo ago

Cognition Emerges from Neural Dynamics. If you like, you can watch the not-bootlegged video of my Society for Neuroscience Presidential Lecture. youtu.be/ie58Ujqy0vA?... #neuroscience

Cortico-basal rhythms reveal how the brain changes during DBS. Lawrence, Little and colleagues describe in a new paper that just dropped in Brain how cortico-basal oscillations track natural everyday movements in individuals receiving deep brain stimulation for PD. @parkinsondotorg.bsky.social

Dear scientists of BlueSky: Wouldn't it be great to learn how large language models work by running experiments on them and analyzing the data? Yeah, you can do that, and I'll show you how. mikexcohen.substack.com/s/ml-on-llms

Dissecting LLMs with ML | Mike X Cohen | Substack

Understand how large language models (LLMs) really work by applying machine learning (ML) methods to their internal activations. Each post explores how LLMs process text, isolate patterns, and generat...

mikexcohen.substack.com

A new study led by @doriswang.bsky.social's lab developed a systematic way to quantify key aspects of gait in patients with #Parkinsons and used machine learning to identify personalized deep brain stimulation (DBS) settings to improve walking: www.ucsf.edu/news/2025/07... @ucsfhealth.bsky.social 🧠📈

Just dropped in @natcomms.nature.com: we show that re-engaging a thalamic–ventral tegmental circuit with deep brain stimulation can reignite consciousness in patients with severe brain injury. Work led by Aaron Warren, with @andreashorn.org @foxmdphd.bsky.social @ others! tinyurl.com/4kz8j89b

A human brain network linked to restoration of consciousness after deep brain stimulation - Nature Communications

In people with severe brain injuries, stimulation restored consciousness by engaging a deep brain circuit for wakefulness—revealing a target that may also guide treatment in stroke and epilepsy.

nature.com

Very excited to share our newest publication on identifying neurophysiological signatures of improved gait using bidirectional DBS devices!

UCSF Neurosurgery@neurosurgucsf.bsky.social · last yr.

New in npj Parkinson's Disease, @doriswang.bsky.social's lab presents an AI approach for identifying personalized deep brain stimulation (DBS) settings to improve walking. The findings lay the groundwork for adaptive DBS systems that adjust in real-time: www.nature.com/articles/s41... 🧠📈 🧪

The fastest-growing neurological disorder is also one of the hardest to recognize. Get an overview of the fundamental diagnostic and clinical tools: 30-minute module » https://loom.ly/axmgg-4

New paper from our group showing how neural traveling waves can be evoked by stimulation of the human brain. www.jneurosci.org/content/earl...

Macroscale traveling waves evoked by single-pulse stimulation of the human brain

Understanding the spatiotemporal dynamics of neural signal propagation is fundamental to unraveling the complexities of brain function. Emerging evidence suggests that cortico-cortical evoked potentia...

jneurosci.org

In @elife.bsky.social: Human single-neuron activity is modulated by intracranial theta burst stimulation of the basolateral amygdala doi.org/10.7554/eLif...