Science named the seemingly unstoppable growth of renewable energy worldwide as the 2025 Breakthrough of the Year. Learn more about last year's #BOTY on #WorldEnvironmentDay: https://scim.ag/4pbMoAv
Boris Louis ๐งช๐ฌ
@borislouis.bsky.social
Postdoc @KU Leuven | R&D | Chemists | Advanced optical imaging | Image processing and data analysis Adventuring the microscopic and the real world !
Smartphone-based super resolution๐ฌ Microscopes are generally costly equipment, limiting availability in remote areas Can we make a high-quality microscope cheaply? This paper makes that vision more real tinyurl.com/defxwzjf With a cost below 350 euros, it delivers single-molecule sensitivity
Microscopy building day 7-9 First images and final checks We finally have a working microscope ๐ฌ After installing the camera, we tackled hardware software communications using @micro-manager.bsky.social Then we performed usual checks: 1) fluorescent marker 2) scale bar 3) bead solution (PSF)
We have a new review out! In this Microscopy & Microanalysis piece, Louisa Mezache and I survey some of the latest commercially available microscope technologies: Nikon NSPARC, Re-scan Gaia, CSR Biotech MI-SIM, refinements to STED, SMLM from Bruker and Abbelightโฆ Check it out with free access:
Advancing Super-Resolution Microscopy: Recent Innovations in Commercial Instruments
Abstract. Super-resolution microscopy techniques have accelerated scientific progress, enabling researchers to explore cellular structures and dynamics wit
academic.oup.com
A universal AI-powered pipeline enables precise 3D analysis of cell morphology and topology within organoid structures. www.nature.com/articles/s41...
I never imagined I would see something like this happen to federally funded research in the US. I am heartbroken for all the researchers whose grants have been terminated and devastated for all the patients whose current (and future) treatments are being impacted ๐งช ๐
Current situation at Harvard Medical School for NIH grants view.u.hms.harvard.edu?qs=3ed8c01b9...
How we analyze porous network @rochalab.bsky.social ๐ฌ๐งช 1) Adaptive thresholding 2)Distance map calculation 3)Watershed transformation 4)Quantification 5)3D rendering Code : github.com/BorisLouis/S... Paper: pubs.rsc.org/en/content/a... #Microscopy #Optics #SciComm #ImageProcessing
An interesting article from Microscopy and Analysis (by Wiley Analytical science)๐งช๐ฌ Useful checklist if you are looking to build a new optical system or currently improving one ! analyticalscience.wiley.com/content/arti...
Practical considerations for building optical setups - 2025 - Wiley Analytical Science
The largest repository of validated, free and subject-focused e-publications and online seminars in analytical science covering latest techniques, equipment, original research, editorials, and industr...
analyticalscience.wiley.com
Deaths from heart disease down 75%, thatโs NIH. Deaths from stroke down 75%, thatโs NIH. HIV/AIDS no longer a death sentence, thatโs NIH. 99% of FDA approved drugs in the last decade, thatโs NIH. Please show this video to anyone who doesnโt understand why the NIH is so important.
๐งโโ๏ธ๐๐จ๐ซ๐ ๐จ๐ ๐ญ๐ก๐ ๐๐ข๐ง๐ ๐ฌ: ๐๐ก๐ ๐๐ฐ๐จ ๐๐จ๐ฐ๐๐ซ๐ฌ โ ๐๐ข๐๐ซ๐จ๐ฌ๐๐จ๐ฉ๐ ๐๐๐ข๐ญ๐ข๐จ๐ง ๐ฌ ๐งช Meet our latest creation @hofkenslab.bsky.social and @rochalab.bsky.social labs: A fully custom upright microscope built entirely from scratch, with no microscope body and no commercial frame. #Optics #SciComm #Microscopy
๐๐๐ฒ ๐ญ๐ก๐ ๐๐ญ๐ก ๐๐ ๐๐ข๐ญ๐ก ๐๐จ๐ฎ ๐ฆโ๏ธ On this Star Wars Day, I revisited Hacksmith Entertainment Ltd. impressive attempt at creating a real-life lightsaber. If you are into starwars and science, you will probably have seen it ! youtube.com/clip/UgkxTLb...
This looks awesome! A new open source optical design software! ๐ฑ Has anyone used it? Is it good? ๐ optiland.readthedocs.io/en/latest/in...
Having both high resolution structural information ๐ฌand functional information ๐งช (in this case, tension) is very challenging, very cool work! #Microscopy #optics
Check out our recent progress using ๐งฌ PAINT kinetics to decode molecular tension in super-resolution force imaging! ๐ฌ Great team effort from Seongho, Adam, Irving, and Kevin! ๐ #DNA-PAINT #tension #integrin #superresolution #adhesion doi.org/10.1002/advs...
๐ฌInterested in imaging in energy science ?๐ฌ Chemical & Biomedical Imaging, a new journal from @acs.org, invited us for a special issue on ๐ฌ๐๐ฆ๐๐ ๐ข๐ง๐ ๐ข๐ง ๐๐ง๐๐ซ๐ ๐ฒ ๐ฌ๐๐ข๐๐ง๐๐ โ๏ธ โก ๐งช And we made the cover ! ๐ Thanks to @alexeychizhik.bsky.social for the amazing design #Microscopy #Optics #SciComm
This week on the Nature Podcast: In the face of massive upheaval, what is the long-term outlook for science in the US and beyond? https://go.nature.com/4k0pdH6
The dismantling of US science: can it survive Trump 2.0?
Hear the biggest stories from the world of science | 30 April 2025
go.nature.com
๐๐จ๐จ๐ค๐ข๐ง๐ ๐๐จ๐ซ๐ฐ๐๐ซ๐ ๐ญ๐จ ๐ฆ๐๐ค๐ข๐ง๐ ๐๐จ๐ง๐ง๐๐๐ญ๐ข๐จ๐ง ๐ข๐ง @spie.org ๐๐ฉ๐ญ๐ข๐๐ฌ + ๐๐ก๐จ๐ญ๐จ๐ง๐ข๐๐ฌ ๐ฌ ๐งช Iโve been invited to give a talk in San Diego (US) in August this year! ๐ฌ If you are attending, I would love to connect arxiv.org/abs/2503.23839 #Microscopy #Optics #SciComm
๐ง ๐๐ฎ๐ข๐ฅ๐๐ข๐ง๐ ๐ ๐ง๐๐ฐ ๐ฆ๐ข๐๐ซ๐จ๐ฌ๐๐จ๐ฉ๐ โ ๐๐๐ฒ #๐ ๐ฌ๐งช โ First, we used the reference laser to project a perfect vertical line through the center of the objective holder. We marked a target on the ceiling for future alignments, an easy trick to save time later #Optics #Microscopy #SciComm
๐ง ๐๐ก๐ข๐ฌ ๐ฌ๐ข๐ฆ๐ฉ๐ฅ๐ ๐ญ๐จ๐จ๐ฅ ๐ฌ๐๐ฏ๐๐ ๐ฆ๐ ๐ก๐จ๐ฎ๐ซ๐ฌ ๐๐ฎ๐ซ๐ข๐ง๐ ๐ฆ๐ข๐๐ซ๐จ๐ฌ๐๐จ๐ฉ๐ ๐๐ฎ๐ข๐ฅ๐๐ข๐ง๐ ๐ฌ ๐งช How do you ensure the optics are aligned straight when building a microscope? For lasers, I often use diaphragms, but again, how do you ensure they are at the exact same height and lateral position? #Optics #Microscopy #SciComm
Harvard scientist Dr. Donald Ingber, who works where medicine and engineering meet, saw federal funding for some of his projects frozen this week as his university clashed with the administration of US President Donald Trump reut.rs/4jkmrfY
Science caught in crossfire of Trump's fight with universities
Scientists see long-term negative impacts on a tradition of partnerships between the government and university researchers dating back to World War Two.
reut.rs
Interesting for those willing to learn how to build microscopes ๐งช๐ฌ #Microscopy #Optics
Today we share our Collection on protocols describing how to build and operate a broad variety of microscopy setups. Let us know which one is your favourite microscope? ๐งช ๐ฌ
๐ฌ ๐๐ฎ๐ข๐ฅ๐๐ข๐ง๐ ๐จ๐ ๐ง๐๐ฐ ๐ฆ๐ข๐๐ซ๐จ๐ฌ๐๐จ๐ฉ๐๐ฌ โ ๐๐๐ฒ #๐ ๐ฌ Exciting times in @rochalab.bsky.social and @hofkenslab.bsky.social Lab !๐งชWe're restarting to build microscopes, and I decided to guide two PhD students (Steven Huysecom and Toon Van Roy) through the process. #Microscopy #optics #SciComm #sts
First invited talk... and I missed my flight ๐ โ๏ธ What a wild 72h from ๐ง๐ช to ๐ธ๐ฌ! Grateful to the organizers who reshuffled things so I could still speak โ and even more shocked (and honored!) to get a prize for young speakers. ๐ฌ๐งช Academia is a rollercoaster๐ Singapore, you were stunning ๐ฟ๐
๐ฌUnveiling charge carrier fate in Solar cell materials with CLIM2.0๐ฌ๐งช Published in ACS Chemical & Biomedical Imaging (@pubs.acs.org,@acs.org) ๐กRead more: pubs.acs.org/doi/10.1021/... Collaboration: Tokyo tech & KU Leuven (@kuleuvenuniversity.bsky.social) #Perovskites #SolarCells #imaging #optics
Looking for a high-throughput characterization tool for your thin films (perovskite, polymer)? We developed a luminescence-based method! Guide to the page pubs.acs.org/doi/10.1021/... @hofkenslab.bsky.social @borislouis.bsky.social #MSCActions #Perovskite #ThinFilms #Materials #imaging
Unveiling the Local Fate of Charge Carriers in Halide Perovskite Thin Films via Correlation Clustering Imaging
As the field of metal halide perovskites matures, a range of compositionally different perovskite films has found a place in efficient optoelectronic devices. These films feature variable local struct...
pubs.acs.org
Amazing week at Gรถttingen University in Prof. @joergenderlein.bsky.social Lab with Toon & @sudiptaseth.bsky.social ! ๐ฌ We performed high-res imaging of optoelectronic materials & collected 200GB+ of data! Thanks to Oleksii Nevskyi & @nradmacher.bsky.social for their help weโll be back! ๐
๐ฌTransforming local intensity fluctuations in solar cells into information with CLIM๐ฌ Borrowing principles of AI and super-resolution optical microscopy, ๐๐๐๐ provide structural and functional information in photo-active materials. Read more here: doi.org/10.1002/adma... ๐ง ๐๐ฎ๐ญ ๐ก๐จ๐ฐ ๐๐จ๐๐ฌ ๐ข๐ญ ๐ฐ๐จ๐ซ๐ค?
Scientists say "good science takes time"โit took us almost 4 years, in fact! Introducing CLIM: A gateway to explore the inner workings of solar cells & delve into local photophysics. @hofkenslab.bsky.social @vaynzof.bsky.social @borislouis.bsky.social onlinelibrary.wiley.com/doi/10.1002/...
In Operando LocallyโResolved Photophysics in Perovskite Solar Cells by Correlation Clustering Imaging
Correlation clustering imaging (CLIM) exploits local intensity fluctuations observed by fluorescence microscopy in metal-halide perovskite films and their solar cells to generate novel contrasts unco...
onlinelibrary.wiley.com
The Correlation Clustering Imaging (CLIM) method developed with @sudiptaseth.bsky.social @hofkenslab.bsky.social, Scheblykin lab, had two milestones last week: 1) Science and innovation award (KU leuven) 2) Accepted in Advanced materials You can read about it here, meanwhile: doi.org/10.26434/che...
Scientists, academics, researchers: Weโre excited to share that @altmetric.com is now tracking mentions of your research on Bluesky! ๐งช
There are already many articles for which there is more attention on Bluesky than on other comparable micro-blogging sites, meaning the academic community and the general public have clearly adopted Bluesky as one of its core places to disseminate and discuss new research. A Place of Joy.
๐ฌ Nanoparticles flocking like birds! Core-shell nanoparticles (200 nm gold, 100 nm silica) swarm under laser irradiation, mimicking flocking birds! ๐ฆ Rotate them by changing light polarization. Learn more in our latest paper @acspublications.bsky.social : pubs.acs.org/doi/10.1021/...