Bosse lab at CSSB Hamburg
@bosse-lab.bsky.social
Illuminating viruses @CSSBHamburg. Check out herpesfolds.org for a comprehensive proteome-wide structural prediction database. A little zoo at home. Equal responsibility dad of three. Views own
On June 8 at 19:00, CSSB together with @adwhamburg.bsky.social will be hosting a panel discussion entitled “Coding Life: Leben gestalten mit biologischen Werkzeugen.” Registration: www.cssb-hamburg.de/codinglife @bosse-lab.bsky.social @uni-hamburg.de @leibnizliv.bsky.social @embl.org
Want to do a PhD combining cryo-EM, AI-driven binder design, and deep virology in a cutting-edge environment and in an international team? We're hiring @CSSB_Hamburg 🔬 You: curious, rigorous, MSc in biochem, biophysics, virology, related Interested? DM me. Please RT 🙏 #PhDposition #cryoEM #virology
W1 = assistant professor
Bosse lab at CSSB Hamburg@bosse-lab.bsky.social · 8mo agoBecome my colleague at CSSB! Hannover Medical School is recruiting a W1 Professor in Systems Virology (m/f/d), based at CSSB Hamburg. Focus: system-wide analysis of virus–virus & virus–host interaction networks. tinyurl.com/msh2449a #Virology #SystemsVirology #AcademicJobs
Become my colleague at CSSB! Hannover Medical School is recruiting a W1 Professor in Systems Virology (m/f/d), based at CSSB Hamburg. Focus: system-wide analysis of virus–virus & virus–host interaction networks. tinyurl.com/msh2449a #Virology #SystemsVirology #AcademicJobs
W1 university professorship for Systems Virology - Region Hannover, Niedersachsen (DE) job with Hannover Medical School (MHH) | 12849342
Hannover Medical School (MHH) invites applications for a W1 university professorship for Systems Virology.
tinyurl.com
Do you want to image RNA in living cells? Check out our new live-cell Click labeling approach. An amazing collaboration with the Meier Lab at UHH and the Wagenknecht Lab at KIT! doi.org/10.1002/anie... Congratulations, especially to Doerte, Eileen, and Iven! Thanks to DFG CRC1648
Live‐Cell RNA Imaging via Clickable TriPPPro Nucleotide Reporters
The intracellular delivery of trans-cyclooctene and bicyclo[6.1.0]nonyne as sterically demanding groups for the inverse electron-demand Diels–Alder was achieved by the triphosphate prodrug (TriPPPro)....
doi.org
f you’re interested in our latest developments have a look at: Comparative Systems Virology Symposium: Jens Bosse youtu.be/PlAcAR1-IJA?si… via @YouTube Thanks to the @czbiohub for organizing and my amazing team for the great data!
Comparative Systems Virology Symposium: Jens Bosse
YouTube video by Chan Zuckerberg Biohub Network
youtu.be
A big thanks to Carolina Arias, Amy Kistler and Noam Stern-Ginossar for organizing an amazing meeting on comparative systems virology yesterday @czbiohub.bsky.social in San Francisco! www.czbiohub.org/events/front...
Frontiers in Comparative Systems Virology Symposium 2025
Be part of this exciting gathering to shape the future of comparative systems virology!
czbiohub.org
📣 Good News! You can still register to join @landaulabcssb.bsky.social for their Functional Amyloid Meeting! landau-cssb.de/registration/ @meytallandau.bsky.social @emilgustavsson.bsky.social @amyloid-sam.bsky.social @jankosinski.bsky.social @bosse-lab.bsky.social @carobarisch.bsky.social
Are you interested in supporting a young international team of scientists as a part-time job? We have an open 25% team assistant position in our lab in Hamburg at the Centre for Structural Systems Biology (CSSB)! Please apply via: mhh.hr4you.org/job/view/327...
Team Assistant (f/d/m)
mhh.hr4you.org
Congratulations to Thomas Mettenleiter for winning this year's Loeffler Frosch Medal awarded for his special service to virology as the long-term President of the Friedrich-Löffler Institut
The third session of our symposium is Bacteria. The session begins on May 8 with a talk by Hinrich Schulenburg from @uni-kiel.de Register today: cssb-hamburg.de/symposium2025 @carobarisch.bsky.social @bosse-lab.bsky.social @topf-lab.bsky.social @landaulabcssb.bsky.social @jankosinski.bsky.social
Check out this video summary of the first day of our upcoming symposium "Mechanisms of Infection - from structure to translation." Register by April 8: t1p.de/gztmj @bosse-lab.bsky.social, @carobarisch.bsky.social, @jankosinski.bsky.social, @meytallandau.bsky.social @topf-lab.bsky.social
Alan Cowman from WEHI @wehi-research.bsky.social will give the second talk in our Parasites session on May 7. Register to attend by April 8: t1p.de/gztmj @carobarisch.bsky.social @bosse-lab.bsky.social @jankosinski.bsky.social @robinsonmeyer.bsky.social
The fourth and final speaker in the Parasites session of our symposium is Ron Dzikowski from The Hebrew University of Jerusalem. Register for the symposium by April 8: t1p.de/gztmj @leibnizliv.bsky.social @fzborstel.bsky.social @uni-hamburg.de @embl.org @helmholtzhzi.bsky.social
CSSB alumnus Michael Filarsky from @unituebingen.bsky.social will give a talk during our "Parasites" session on May 7. Take a look at the symposium programme here: t1p.de/h48ek @leibnizliv.bsky.social @fzborstel.bsky.social @helmholtzhzi.bsky.social @uni-hamburg.de
The second session of our symposium is "Parasites". Emily Derbyshire's talk entitled "Interdisciplinary approaches to reveal parasite vulnerabilities" will start the session. Register by April 8: t1p.de/gztmj @meytallandau.bsky.social @carobarisch.bsky.social @bosse-lab.bsky.social
On May 7, Ilaria Ferlenghi from GSK will give a talk entitled "Fast-Track to Immunity: The Fusion of Structural Biology, AI, and ML in Vaccine Innovation" Register today: t1p.de/gztmj @carobarisch.bsky.social @bosse-lab.bsky.social @jankosinski.bsky.social @meytallandau.bsky.social
🚨 Save the date! 🚨 We're thrilled to announce our International Symposium on Cell & Structural Biology of Host-Pathogen Interaction 📅 Sept 10-12, 2025 📍 @cssbhamburg.bsky.social Hamburg Registration starts soon For more info: humansandmicrobes2025.de
Our symposium "Mechanisms of Infection: from structure to translation" will take place from May 7-8. Over the next weeks, we will be introducing our 15 confirmed speakers. Sriram Subramaniam from the University of British Columbia will be giving the key note. www.cssb-hamburg.de/symposium2025
The first session of our symposium "Mechanisms of Infection: from structure to translation" is Viruses. Ben tenOever from New York University will give the first talk in this session. t1p.de/xu79k @carobarisch.bsky.social @bosse-lab.bsky.social @topf-lab.bsky.social @jankosinski.bsky.social
About 1,5 years ago I predicted in a little writeup for the ExC RESIST that ever more capable LLMs will soon make scientific review articles obsolete. From the initial results I have from #OpenAIs #DeepResearch, this is happening very soon…
We are very excited that our in-situ structural analysis of the Ebola virus nucleocapsid assembly cascade is now published in @cellpress.bsky.social!
Conclusion of RNA assessors in #CASP16 - we are still in the “template” phase. Prediction of nucleic acids structure is still challenging for targets without templates, often relying on intuition. No big leap in accuracy since CASP15. AI based methods have not (yet?) made a major difference.
Stone conclusion by hearsay from day 1 at #CASP16 all top methods used AF3 somehow. Improvements are made by increased sampling (FFT etc), ranking of models still a challenge. Some improvement on antibodies.
Conclusions from RNA section at #CASP16, without a template all fail. All small targets had a template.
Conclusion for ligand session in #casp16, without a template methods fail
#CASP16: are we making progress in predicting protein-protein complexes?Not much in general, but …. One method (Kozakov Vajda) shows great improvement in predicting structure of antibody-antigen complexes. 🧪 🧬
