Brian

@brianmackenna.bsky.social

Pharmacist | MPH | Data

Are tocilizumab & sarilumab equally effective for severe COVID-19? A new @natcomms.nature.com study of 10k+NHS hospital patients in England 🏴󠁧󠁢󠁥󠁮󠁧󠁿 & Scotland 🏴󠁧󠁢󠁳󠁣󠁴󠁿 shows no difference in 28-day mortality or time to discharge. Both IL-6 inhibitors are equally effective options www.nature.com/articles/s41...

Tocilizumab versus sarilumab among adults hospitalised with COVID-19: target trial emulation across England and Scotland - Nature Communications

Using electronic health record databases in England and Scotland, this study compared tocilizumab and sarilumab in over 10,000 hospitalised COVID-19 patients and found no meaningful difference in surv...

nature.com

HISTORIC MOMENT Today at 14:40 Dr Mark Russell from KCL pressed the button to execute the first ever job on the new OpenSAFELY service. Until today, OpenSAFELY was COVID only. Now we are open to critical analyses that improve all patient care, on GP records, securely, at scale. PICS! THREAD!

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Inaugural Lecture Klaxon! Our magnificent CTO Seb Bacon is a hero of the modern age, and now PROFESSOR Seb Bacon... Come to his inaugural lecture in Oxford! OpenSAFELY! OpenPrescribing! TrialsTracker! OpenCorporates! Open Code! Open Everything! www.bennett.ox.ac.uk/blog/2026/05... bacon.boutique

"On The Record" - Seb Bacon’s Inaugural Lecture | Bennett Institute for Applied Data Science

Come and join Seb for his inaugural lecture as the first-ever Professor of Practice at the Nuffield Department of Primary Care Health Sciences

bennett.ox.ac.uk

Ireland has amongst the highest over-the-counter codeine sales internationally. Meanwhile opioid prescribing in Ireland has risen, whilst falling in England. I wrote about why the Irish health service needs to confront its opioid problem on Linkedin: www.linkedin.com/pulse/irish-... brief🧵

The Irish health service needs to confront its opioid problem

Recent research shows Ireland has amongst the highest over-the-counter codeine sales internationally, and that prescriptions for painkillers, particularly opioids, have risen steadily over the last de...

linkedin.com

Ireland has amongst the highest over-the-counter codeine sales internationally. Meanwhile opioid prescribing in Ireland has risen, whilst falling in England. I wrote about why the Irish health service needs to confront its opioid problem on Linkedin: www.linkedin.com/pulse/irish-... brief🧵

The Irish health service needs to confront its opioid problem

Recent research shows Ireland has amongst the highest over-the-counter codeine sales internationally, and that prescriptions for painkillers, particularly opioids, have risen steadily over the last de...

linkedin.com

OpenSAFELY is open from today! Huge thanks to all who supported this vast collaboration: whole population GP data; in a productive platform; innovative privacy protections; unprecedented support from professions, privacy campaigners; &c Now it's over to users! www.bennett.ox.ac.uk/blog/2026/02...

OpenSAFELY news: you can apply to do non-COVID research, from today! | Bennett Institute for Applied Data Science

We are delighted to announce that - from today - you can submit applications to the OpenSAFELY service for non-COVID-19 studies.

bennett.ox.ac.uk