Thanks so much to @crestoptics.bsky.social for highlighting our research!

CrestOptics@crestoptics.bsky.social · 3mo ago

Bacterial "Social Life” in 3D: Prof. Andrew Bridges on X-Light V3 Imaging Insights: tinyurl.com/mry28tpm @bridgesbio.bsky.social & team (@cmuscience.bsky.social) highlight 2 key benefits for biofilm research: 📐Micro-Scale precision ⏱️High-speed, low-impact imaging #ExpertTestimonials #TheV3Advantage

🔬#ImageOfTheWeek | Powered by the #Bridges Lab Unveiling the #Biofilm Journey. Biofilm cells (Magenta); Biofilm matrix components (Yellow).Thank you to @bridgesbio.bsky.social & team at @cmu.edu for capturing these images. Stay tuned for more! tinyurl.com/3yr5herp #TheV3Advantage #FluorescenceFriday

New preprint: "A branching cell-fate decision in biofilm dispersal enables long-term surface persistence." When V. cholerae biofilms disperse, it isn’t a uniform exit, rather, an opportunity to bet-hedge. A subpopulation of cells stay behind, primed for biofilm regrowth. doi.org/10.64898/202...

Congratulations to @emmynguyen.bsky.social and our wonderful collaborators. Here we uncover and characterize a periplasm protein that modulates broad physiological changes to V. cholerae by controlling a two component system!

Emmy Nguyen@emmynguyen.bsky.social · 8mo ago

Thrilled to share that my first-author paper is now published in Nature Communications! 🎉 Huge thanks to my PI, Dr. Drew Bridges (@bridgesbio.bsky.social), my collaborators, and all the incredible lab members for their support throughout this project www.nature.com/articles/s41...

Thrilled to share that my first-author paper is now published in Nature Communications! 🎉 Huge thanks to my PI, Dr. Drew Bridges (@bridgesbio.bsky.social), my collaborators, and all the incredible lab members for their support throughout this project www.nature.com/articles/s41...

A small periplasmic protein governs broad physiological adaptations in Vibrio cholerae via regulation of the DbfRS two-component system - Nature Communications

A two-component system, DbfRS, regulates biofilm formation in Vibrio cholerae. Here, Nguyen et al. identify a small periplasmic protein that controls the activity of the system’s receptor, and show th...

nature.com

The Department of Biological Sciences at Carnegie Mellon is seeking an innovative and accomplished scientist to serve as our next Department Head. Join us in shaping the future of biological sciences in Pittsburgh. jobs.sciencecareers.org/job/675374/h...

Head of the Department of Biological Sciences - Pittsburgh, Pennsylvania job with Carnegie Mellon University | 675374

Head of the Department of Biological Sciences Carnegie Mellon University 4400 5th Avenue Pittsburgh, PA 15213   The Department of Biological Scienc...

jobs.sciencecareers.org

A future perspective article on the next 10 years in microbial molecular biology and physiology is online now. journals.asm.org/doi/10.1128/... 🧵👇

An exciting future for microbial molecular biology and physiology | mBio

The first two bacterial genomes were sequenced nearly 30 years ago (1, 2). The cost of one of those sequences, that of Haemophilus influenzae, was over 1,000,000 U.S. dollars and took multiple years (...

journals.asm.org

I'm delighted to share a useful FREE web-based app portal of powerful bioinformatics tools for microbial genomes and shotgun microbiome sequences! It's called Micromics and is built by Middle Author Bioinformatics, led by co-founder @ironark.bsky.social omix.midauthorbio.com

Congratulations to @vscooper.micropopbio.org on his election to become the next president of the @asm.org! asm.org/Press-Releas...

Excited to host a session at @asm.org #Microbe2025 in LA. Our session is entitled, "Acting As a Unit: Regulation of Microbial Collective Behaviors From Molecules to Populations." Please join us and submit an abstract! www.abstractsonline.com/pp8/#!/20974... #Microsky

Excited to share our latest, "Biofilm dispersal patterns revealed using far-red fluorogenic probes." @plos.bsky.social We developed a cell-labeling strategy using far-red dyes to image dense microbial communities (where fluorescent proteins often do not work well) journals.plos.org/plosbiology/...

Biofilm Starter Pack on the Blue place go.bsky.app/HF1jeCQ

Has anyone had the time to setup a starter pack for the brave 🙌🏻 early adopter scientific journals that have migrated to BlueSky? 🧪🦠🧬💉🩻🔬🧫

...and tag your own posts with #MicroSky if appropriate. it helps (=be your own algorithm 😌)

Has anyone made a microbiology or bacteriology starter pack??

Another starter pack of fine fine folks - New PIs! We're all figuring it out together! Please do (self-)nominate go.bsky.app/KJXNgfZ

Thrilled to have presented my research in the lab of @bridgesbio.bsky.social at three conferences this year: Bacteria and Phages, ABASM, and Rust Belt Microbiome. Grateful for the chance to share my work and connect with inspiring scientists. Can't wait to see what future conferences bring!

For those moving from X/Twitter, I just used this excellent tool to transfer 1000+ Followings in 5 min. chromewebstore.google.com/detail/sky-f...

Sky Follower Bridge - Chrome Web Store

Instantly find and follow the same users from your Twitter follows on Bluesky.

chromewebstore.google.com

Endorse this outstanding essay by @hormiga.bsky.social written in 2016, republished here: TLDR: 1. Keep up our research. 2. Teach critical thinking. 3. Advocate publicly for evidence-based decision making. 4. Build diverse and inclusive academic communities open.substack.com/pub/sciencef...

Being a Scholar in Trumpian times

Some thoughts about doing the right thing as an academic in an autocracy

open.substack.com

Friends, I wrote up a quick guide to getting started on Bluesky for folks who are used to old Science Twitter. Please share it with your folks who are joining. And please let me know if I missed anything or got anything wrong. 🧪 www.southernfriedscience.com/bluesky-is-n...

Bluesky is now open. Science Twitter, here’s how to use it!

The once-great science twitter is, depending on who you talk to, either dying or dead. Once a vibrant place for many discussions related to my fields of marine biology, ocean conservation, and publ…

southernfriedscience.com

We determine that additional pathogenic organisms also exhibit multicellular community formation in response to lysis. Given the pervasiveness of lysis in the environment, we propose that lysis sensing is a threat-agnostic mechanism by which bacteria can gauge endangerment. (4/4)

We identify the cell lysis signal as an abundant cytoplasmic polyamine, norspermidine, which is detected by an inner-membrane receptor, MbaA, that in turn drives biofilm formation. (3/4)

We find that the mechanism underlying this observation is a process we refer to as "lysis sensing"...whereby surviving cells sense a signal released by the death of their kin. (2/4)

Our first paper from the lab! We find that upon exposure to lytic phages, the pathogen V. cholerae rapidly lyses, but then recovers, with surviving cells exhibiting robust biofilm formation. www.nature.com/articles/s41... (1/4)

A few weeks ago we wrapped up our EvolvingSTEM 🧫🧪🧬curriculum with the 8th graders at Carmalt Elementary in Pittsburgh. KDKA was there to profile their partnership with us. Hope it makes you smile 😊 too! www.cbsnews.com/pittsburgh/v...

Had a blast writing a commentary #msphere on “Biogeography of a human oral microbiome at the micron scale” by @jmarkwelch.bsky.social et al. The work in this paper made me want to be a microbiologist. I vividly remember an MBL lecture by Gary Borisy on the topic when I was a grad student.

🎉Our work on the origins of innate immune proteins is now published in PLOS Biology! Great insights from postdoc Ed Culbertson on the connections between mammalian immunity and bacterial anti-phage immunity🦠 plos.io/46SfBqM Original tweet thread on our findings here: x.com/tera_levin/sta…