Need help! The most cost effective sequencing service for ready libraries for single-cell ATAC-seq? Share your best tips! Have money, just not lots of it. #sequencing #singlecell #atacseq
Eliisa Kekäläinen
@eliisakekalainen.bsky.social
MD PhD, associate professor of clinical microbiology and immunology, physician-scientist at University of Helsinki & Helsinki University Hospital 🇫🇮. #thymus #IEI diagnostics #HSCT . Personal account, she/her. I am too interested in everything.
Erittäin kannatettava aloite ja allekirjoitin
Kansalaisaloite korjaamisen tekemisestä halvemmaksi, jotta ei aina tarvitsisi ostaa uutta. "Esitämme arvonlisäverolain muuttamista siten, että määriteltyjen korjauspalveluiden arvonlisäverokanta alennetaan alempaan luokkaan." www.kansalaisaloite.fi/fi/aloite/15...
👀 Our latest review is out in Immunological Reviews. We revisit the search for #stemness in an involuting organ - and the paradox at the heart of #thymus biology 💡 #Thymus #StemCells #Regeneration #Immunology #TranslationalScience #OrganReconstruction @crick.ac.uk @ucl.ac.uk shorturl.at/u6xJK
The Thymus Regeneration Paradox: The Search for Stemness in an Involuting Organ
The thymus is emerging as a model for studying organ regeneration and stem cell biology. While research has long focused on how antigen-presenting cells shape the T cell repertoire, recent discoverie....
shorturl.at
Very few things in life are more boring than ice fishing.
Finland just won against Switzerland in Olympic icehockey quarter finals. This guy made the winning goal. Here he is giving an interview. Note the emotional range. 🇫🇮🇫🇮🇫🇮
Been a busy few lonths so a bit late: new manuscript out from the lab! We created and evaluated healthy reference ranges for pediatric deep immunophenotyping, aiding clinicians diagnosing inborn errors of immunity. Great effort from 1st authors Elli & Anssi ❤️. link.springer.com/article/10.1...
Evaluating Pediatric Reference Ranges for Extended Immunophenotyping from a Finnish Cohort against Published References - Journal of Clinical Immunology
Flow cytometric immunophenotyping of lymphocytes and dendritic cells, and functional lymphocyte mitogen response tests are used in the diagnostics of inborn errors of immunity (IEI), especially in ped...
link.springer.com
Today we got our new imaging system for automated spatial proteomics installed! Maria Semenova is already eager to image thymuses. Thank you @zeiss-microscopy.bsky.social - we are excited to be the first users in Finland for the new system integrating imaging and fluidics. Funded by @erc.europa.eu
WE ARE HIRING 💥 Do you want to become our new project coordinator? More details on the University of Helsinki webpage. Application period until September 10th - be quick! 🧪🧬🦠🧫🔬https://jobs.helsinki.fi/job/Helsinki-PROJECT-COORDINATOR/828168902/
PROJECT COORDINATOR
PROJECT COORDINATOR
jobs.helsinki.fi
Stimulating immune cells in vitro is a common experimental lab model. We profiled 150K blood immune cells treated with 11 different stimuli to compare the effects. The data are freely available for researchers. See the preprint for our findings and to access the data 🧪 doi.org/10.1101/2025...
Unpaid advertisement for the Finnish 🇫🇮 tourism agency: if it is unbearably hot where you are now (like New York), come to Finland. It is nice and chilly at 14 degrees of Celsius (57 F) now. #chillescape
New results on the role of circulating T follicular (cTfh) and T peripheral helper (cTph) cells in type 1 diabetes out at @eurjimmunol.bsky.social: onlinelibrary.wiley.com/doi/10.1002/... #immunosky #T1D #autoimmunity
The Frequency but not the Phenotype of Circulating Peripheral T Helper Cells is Increased at Later Stages of Progression to Type 1 Diabetes
Frequencies of circulating T peripheral helper (cTph) and activated T follicular helper (cTfh) cells increase close to the diagnosis of clinical type 1 diabetes, but not at the onset of autoimmunity.....
onlinelibrary.wiley.com
Äidit huutakaa. Kehtolaulujen asemesta huutakaa. Huutakaa suoraa huutoa kaikkialla maapallolla yhteen ääneen. Naiset huutakaa. Pysäyttäkää liikenne, tehtaat, aseitten valmistus, unet. Seisokaa keskellä toreja ja teitä ja huutakaa.
OK, everything is not done, I give up. It is not raining, garden needs tending, and today it is 20 hrs of daylight so must move my focus there. Hyvää juhannusta 🔥🔥🔥🔥🔥! 🇫🇮
In Finland 🇫🇮 we have this thing called ”everything must be done before midsommaren”. I have three days. Bring it on.
I agree the thymus likely presents all key epitopes for T cell tolerance. But studies based only on transcriptional data without testing each mimetic cell’s role should be viewed cautiously and given lower priority. #thymus #tolerance #immunology
Developmental trajectory and evolutionary origin of thymic mimetic cells - Nature
In mice, tissue-mimetic cells appear in thymus in two distinct waves, creating two distinct pools of mimetic cells, each expressing antigens characteristic of different cell types.
buff.ly
Teamwork makes the dream work! Kekäläinen lab participating to the #HelsinkiPride month (a bit late to the game but our office was under renovation). #PrideMonth 🧪
Miten tehdään huippuyliopisto: riittävästi rahaa, panostuksia erityisesti perustutkimukseen. www.hs.fi/visio/art-20...
HS Visio | Rahalla saa ylivoimaisen yliopiston
Helsingin yliopisto putosi jo kertaalleen maailman sadan parhaan yliopiston listalta. Samalla listalla Kööpenhaminan yliopisto on vuodesta toiseen Pohjoismaiden paras. HS kysyi Kööpenhaminassa, mistä ...
hs.fi
Found pinned to the notice board at Dept. of Bacteriology and Immunology, University of Helsinki. Finnish academics supporting the good fight by Harvard University. The North Stands with You. 🧪@harvardcellbio.bsky.social @helsinki.fi
Personal news: I have been appointed by the rector of @helsinki.fi to a tenure-track associate prof position in Clinical Microbiology and Immunology! My affiliations are with the Faculty of Medicine and HiLIFE, Institute of Life Sciences @helsinki.fi . Humbled and excited to start this new journey!
Postdoc opening in Pia Dosenovic's lab at Karolinska Institutet, "B cell-mediated immunity with a focus on basic immunological questions related to vaccine development" #Immunology #ScienceJobs #ImmunoSky ki.varbi.com/what:job/job...
Postdoctoral studies in Immunology (scholarship)
Do you want to contribute to top quality medical research? The Department of Microbiology, Tumor and Cell Biology (MTC) at Karolinska Institutet conducts research and teaching within immunology, inf
ki.varbi.com
These times have proved that it is good to have something like Section 16.3 of Finland's Constitution: 'The freedom of science, the arts and higher education is guaranteed'.
Interested in translational human immunology? We are currently recruiting a PhD student or a post-doc to work on an exciting project to to study immune changes leading to the development of type 1 diabetes. #immunosky #sciencejobs uef.varbi.com/en/what:job/...
Postdoctoral Researcher/Doctoral Researcher/Project Researcher, Translational Immunology
The University of Eastern Finland is inviting applications for a Postdoctoral Researcher/Doctoral Researcher/Project Researcher (Translational Immunology) position in Kuopio. The position will be fill
uef.varbi.com
LLMs and open science are not meant to flood the already congested scientific literature with junk but should help us to be more creative. #immunosky #medsky 🧪 Low-quality papers are surging by exploiting public data sets and AI | Science | AAAS www.science.org/content/arti...
Low-quality papers are surging by exploiting public data sets and AI
Paper mills are also likely contributing to “false discoveries”
science.org
Life of a Northener: in the winter you barely are alive, just doing the minimum and would preferably just sleep. Spring arrives and you have started 12 new projects at home and work, barely sleep and dig in the garden untill wee hours.
a black banner that says we the north
ALT: a black banner that says we the north
media.tenor.com
"Science is an investment. We will put forward a new 500 million package for 2025-2027 to support the best and the brightest researchers and scientists from Europe and around the world." — President @vonderleyen.ec.europa.eu at the ‘Choose Europe for Science' event at La Sorbonne 🇫🇷
💵🥳
The ERC welcomes the offer of substantial additional budget from @ec.europa.eu for the development of a new ERC funding instrument offering larger, longer-term grants, as announced by President Ursula Von der Leyen at the Sorbonne this morning. 👉 europa.eu/!NTYTTV
Majority of Finns does not approve of the planned tax cuts for the highest income percentiles. I disapprove the planned cuts even though these cuts would and will benefit me directly. I won’t work any more because of them. It is more important to me that my society is equal and supportive. 🇫🇮
Suomalaisten selkeä enemmistö tyrmää hallituksen aikeet keventää erityisesti suurituloisten verotusta.
Just in time for Eurovision. 🔥❄️ from 🇫🇮 dr. Sulo Roukka
🎉 The overall winner of this year’s #DanceYourPhD contest is Sulo Roukka, who meshed lab experiments with dance moves under flashing lights as sequined lab mates analyzed hot chilies and mint with fancy footwork. Watch the winning work and learn more about the category winners: scim.ag/4lSpjCl
🚨 Happening TODAY! Join us for the special #DayofImmunology 2025 Live Webinar 15:00–18:00 CEST 🗓️ Explore how the immune system shapes brain health + new insights in #NeuroImmunology 🔬✨ 🔗 Register now — immunohub.iuis.org/iuis/2024/we... @yefis-immunology.bsky.social @iuis-online.bsky.social
Postdoc / MSc project available (8/12 months by 8/2026; welcome to apply more with us)! If you're interested in host-microbe interactions and (ideally) both wet lab and data, let me know! Example of our research - now working also with pigs and fish: bmcbiol.biomedcentral.com/articles/10....
Impacts of maternal microbiota and microbial metabolites on fetal intestine, brain, and placenta - BMC Biology
Background The maternal microbiota modulates fetal development, but the mechanisms of these earliest host-microbe interactions are unclear. To investigate the developmental impacts of maternal microbi...
bmcbiol.biomedcentral.com