If you want to tap directly to @gregory-ms.com and its neurology knowledge base, add this URL to your chosen AI as a connector/MCP server: gregory-ai.brain-regeneration.com/mcp Try it out and tell me what would be a nice addition.
Bruno Amaral
@brunoamaral.eu
I want the web to be a better place. Communication Strategist, Creative Tinkerer. Weirdness and occasional posts in Portuguese. Helping Multiple Sclerosis research with @gregory-ms.com and https://brain-regeneration.com
For me, having Claude run a search online or otherwise is a trap. It gets what I asked for + the kitchen sink. It's being thorough but it doesn't carry my intention and goal. I wanted to know about MS trials for a particular medicine in China, I got back "here's all about MS trials in China!"
Claude is very good at "unbreaking" clinical trial registries. This time it found a workaround to get permanent URLs in the Chinese Registry. And this isn't even the best, for the EU registry, it told me about an undocumented API.
Our lab just released our AI Behavioral Observatory open source. It lets you run statistically valid tests on how AI behavior changes under various types of prompts. We have been using it for our own studies & I think it could help others do similar work. gail.wharton.upenn.edu/research-and...
From building an AI research tool to prompting the research itself
gail.wharton.upenn.edu
AI is not the miracle cure we were promised, and I hoped for Multiple Sclerosis. I use it to build bridges, connect the dots, and make a space where different perspectives on neurology meet, the Brain-Regeneration knowledge hub. brunoamaral.eu/how-ai-is-sa...
I'm not a developer but I built a research observatory for my disease
I don't write code. Three machine learning models read 50,000 papers so my neurologist didn't have to.
brunoamaral.eu
I accidentally ended up with a personal health tracker app on my phone after asking Opus 5 if there was a better way to save that information in Obsidian
I was reluctant and hitting guardrails with Claude Fable. I was wrong and it turned out to be a huge gain to improve the data we have for #ClinicalTrials across the world. github.com/brunoamaral/...
Release v26 The Fable edition · brunoamaral/gregory-ai
While Anthropic was going back and forth with access to Claude Fable, I was reluctant. Why would I was time on something about to go away? And the few attempts I made to use it to help my Multiple ...
github.com
Apps like Granola make it easy to transcribe conversations without asking for consent. Those transcripts are a subpoena honeypot. werd.io/people-are-t...
People are transcribing your conversations without asking. That puts you at risk.
Apps like Granola make it easy to transcribe conversations without asking for consent. Those transcripts are a subpoena honeypot.
werd.io
New preprint: #Microglia don't just clear debris - they undergo a massive metabolic overhaul after phagocytosis, including adaptive mitochondrial changes, which may make them pro-regenerative! 🥳🧠💪 #Neuroscience #Mitochondria #Metabolism #BioRxiv www.biorxiv.org/content/10.1...
Metabolic and transcriptional adaptations to phagocytosis sustain microglia functionality and regenerative properties
Phagocytosis of apoptotic cells, or efferocytosis, is a tightly regulated process that ensures tissue homeostasis and prevents mounting inflammatory responses. In the brain parenchyma, it is executed ...
biorxiv.org
Pretty cool idea, visualising your diary as a network. www.reddit.com/r/ObsidianMD...
From the ObsidianMD community on Reddit
Explore this post and more from the ObsidianMD community
reddit.com
A Ordem dos Fisioterapeutas emitiu um "parecer" sobre uso de IA, sem falar no elefante da sala. Não se pronunciam a respeito da Sword Health e acho que isso era importante para mostrarem uma postura mais concreta e uma boa espinha dorsal. ordemdosfisioterapeutas.pt/pt/noticias/...
Ordem aprova parecer sobre utilização de inteligência artificial e tecnologias digitais na prestação de cuidados de Fisioterapia - Ordem dos Fisioterapeutas
A Ordem dos Fisioterapeutas aprovou o Parecer 0001.2026.P.B — Utilização de Inteligência Artificial e Tecnologias Digitais na Prestação de Cuidados de Fisioterapia.
ordemdosfisioterapeutas.pt
Keeping track of #ClinicalTrials isn't easy. 3 main registries, each with their way to keep data. Claude Fable is helping me join them in @gregory-ms.com so it's easier for you to know which countries are involved, the recruitment status, and criteria.
I have over 29k open-access PDF articles right next to me. Properly indexed and named. They represent 5 years of all the #MultipleSclerosis research. Imagine if the cure is hiding in this box, and I'm too stupid to know how to open it. If anyone wants a crack at it, I'm happy to share. #datamining
Love it or hate it, it is undeniable that some AI work is better than what most humans can produce.
10.10.2026"...Following the company’s press release dated April 16 [1], three clinical studies—which the company currently considers non-priority and for which patient enrollment had been suspended—are being discontinued, namely:
@rcarmo.bsky.social brought back something very useful for people in #PublicRelations and sales, an app that gives you context about the page and person you're seeing in the current app: taoofmac.com/space/blog/2...
The Return of Shelf
Remember when the internet was young, there was a finite (but quite large) set of personal sites, personal contact actually mattered and you...
taoofmac.com
New #ClinicalTrial to watch: INDAMS is testing indapamide, an old blood-pressure pill, to see if it can slow disability in PPMS & SPMS. Lab work shows neuroprotection and blood-brain barrier crossover. Early "go/no-go" study. euclinicaltrials.eu/search-for-c... #MSchat #MultipleSclerosis #neurology
Search for clinical trials - EMA
euclinicaltrials.eu
The job market is going to be flooded with AI auto-applications. We may even have to go back to hiring people we know or who were referred by someone we trust! github.com/MadsLorentze... #AI
GitHub - MadsLorentzen/ai-job-search: AI-powered job application framework built on Claude Code. Fork it, fill in your profile, and let Claude evaluate jobs, tailor CVs, write cover letters, and prepa...
AI-powered job application framework built on Claude Code. Fork it, fill in your profile, and let Claude evaluate jobs, tailor CVs, write cover letters, and prepare you for interviews. - MadsLorent...
github.com
TIL that html can have bibliographic entries. <d-bibliography src="bibliography.bib"></d-bibliography>
Made Claude Fable review the ML models for @gregory-ms.com and it found problems that fixed on it's own. The new version is up on brain-regeneration.com and we are reviewing the full 40k clinical papers which should take about 6 hours.
Brain Regeneration Observatory
Accelerating research into brain regeneration and myelin repair through comprehensive tracking of scientific literature and clinical trials.
brain-regeneration.com
The most interesting Fable tip I've heard so far is to let the model use its own judgement as much as possible I told it "For all coding tasks use your judgement to decide an appropriate lower power model and run that in a subagent" and it seems to be saving tokens simonwillison.net/2026/Jul/3/j...
Fable's judgement
One of the most interesting tips I got from the Fireside Chat I hosted with Cat Wu and Thariq Shihipar from the Claude Code team at AIE on Wednesday was …
simonwillison.net
