As part of @sfb1638.bsky.social in 𝐌𝐞𝐦𝐛𝐫𝐚𝐧𝐞 𝐑𝐞𝐦𝐨𝐝𝐞𝐥𝐢𝐧𝐠, we are committed to developing computational tools that make complex membrane simulations more accessible, reproducible, and scalable for the scientific community. Today, we are happy to share the public release of 𝐎𝐩𝐞𝐧𝐌𝐞𝐦𝐛𝐫𝐚𝐧𝐞𝐁𝐮𝐢𝐥𝐝𝐞𝐫 v1.2.1

Come join our institute as a Full Professor! We are looking for outstanding scientists to join a highly collaborative and internationally recognized research environment in the beautiful city of Heidelberg! @uniheidelberg.bsky.social @sfb1638.bsky.social #TRR186 #TRR319

Full Professorship (W3) for "Biochemistry" (f/m/d) - Heidelberg, Baden-Württemberg (DE) job with Universität Heidelberg | 12859405

The Heidelberg University Biochemistry Center (BZH) is seeking to fill a   Full Professorship (W3) for “Biochemistry” (f/m/d)     as soon as possib...

nature.com

🚨 Lipid Time 🚨 New preprint out! Using high-throughput Martini 2 simulations, we studied ~5,000 transmembrane helices in a phase-separating membrane. Most helices preferred disordered environments, some localized at domain interfaces, but none in the liquid-ordered phase! doi.org/10.64898/202...

Today’s @bzh-hd.bsky.social seminar is on Cross-linking mass spec #XL_MS & how it can be used in cell biology, given by Fan Liu. Thx @cpaulino.bsky.social for inviting her!!!

Kicking off the year with a new scientific chapter from one of our group leaders @fabiololicato.com @sfb1638.bsky.social @uniheidelberg.bsky.social

Fabio Lolicato@fabiololicato.com · 7mo ago

🚨 First lipid paper of the year! 🚨 Combining neutron reflectometry and MD simulations, we show how α-fetoprotein interacts with lipid membranes, depending on composition, with implications for biomarker detection and biosensing! Great start to 2026! Congrats to the team! 🎉 @sfb1638.bsky.social

🚨We are hiring🚨 We’re looking for a part-time Administrative Assistant (19.75 h/week) starting 1 March 2026. You’ll support finance tasks, organise events, manage website updates, and work with a friendly team in an international environment. 👉 More information below 📩 Apply until 4 January 2026

🎄 𝐂𝐡𝐫𝐢𝐬𝐭𝐦𝐚𝐬 𝐋𝐢𝐩𝐢𝐝 𝐓𝐢𝐦𝐞! 🎄 Thrilled to share a special pre-holiday gift to 𝗟𝗼𝗹𝗶𝗰𝗮𝘁𝗼 & 𝗡𝗶𝗰𝗸𝗲𝗹 𝗟𝗮𝗯𝘀! 𝐏𝐈(𝟒,𝟓)𝐏𝟐 𝐚𝐬𝐲𝐦𝐦𝐞𝐭𝐫𝐲 is essential for the unconventional secretion of 𝐅𝐆𝐅𝟐, driving rapid formation of a lipidic membrane pore, enabling membrane translocation ⏩⏩ 🔗 www.nature.com/articles/s41...

Thrilled to share that Dr. Jirka Peschek, one of our BZH group leaders, is receiving the Chica & Heinz Schaller Award for his RNA biology research 🧬 🏆 €100,000 research funding. Ceremony today, 26 Nov, 5:30 PM, Marsilius Kolleg (INF 130.1). Congrats, Jirka! 🎉

🚨Paper alert! 🚨 Exciting work from our group leader @mandyjeske.bsky.social ! Using ReLo + AlphaFold, they mapped Drosophila piRNA factor interactions—uncovering new links in transposon silencing and genome integrity. 👇👇👇

Mandy Jeske@mandyjeske.bsky.social · 10mo ago

Excited to share our new @narjournal.bsky.social paper! Using ReLo and AlphaFold, we described a network of interactions between Drosophila piRNA pathway factors suggesting new links how they coordinate to ensure transposon silencing and genome integrity. academic.oup.com/nar/article/...

🎉 Congratulations to the winners of the Best Poster Awards at #BiomembraneDays2025 sponsored by @lipotype.bsky.social 🏆Manpreet Kaur (with @fabiololicato.com &W. Nickel) 🏆Jana Kroll (@janakroll.bsky.social @mdc-berlin.bsky.social) 🏆Ha Ngoc Anh Nguyen (with @jamessaenz.bsky.social) 🚀Science rocks!

Now @bzh-hd.bsky.social Jonathan Friedman is talking in #mitochondria organization

🚨 Preprint Alert 🚨 #LipidTime Excited to share our new preprint! 🎉 We propose a hypothesis for how FGF2 crosses the plasma membrane — a mechanism that may reflect a general principle of membrane remodeling. 🔑 Key idea: Non-bilayer lipid accumulation alters membrane properties, driving remodeling.

bioRxivpreprint@biorxivpreprint.bsky.social · 11mo ago

Nanoscale PI(4,5)P2 partitioning driven by FGF2 oligomerization triggers membrane pore formation https://www.biorxiv.org/content/10.1101/2025.09.11.675533v1

Thrilled to have contributed to this amazing work! Thanks for having us on board 🙌 Huge shoutout to our super-talented postdoc #MelanieKönig for her outstanding efforts 💫. And big congratulations to everyone involved in this terrific team effort! 🎉 @sfb1638.bsky.social @bzh-hd.bsky.social

PfefferCryoLab@pfeffercryolab.bsky.social · 12mo ago

We are excited to share our latest work elucidating the structural basis for how augmin binds to microtubules. Out just now @natcomms.nature.com : www.nature.com/articles/s41...

A bit late—but better late than never! Honored to present my work at #EBSA2025 in Rome a few weeks ago. I first attended EBSA in 2017 in Edinburgh and haven’t missed one since. This year in Rome—my first home—was especially meaningful. 🇮🇹 Already looking forward to Berlin 2027—my new home! 🇩🇪

Looking for a PhD position? The Schuck lab has an opening for a student interested in finding out how human cells control the size of their endoplasmic reticulum. Please visit www.bzh.uni-heidelberg.de/schuck and navigate to 'Open Positions'.

Do you want to become our colleague? We are looking to fill a part-time (50%) permanent position for a Technical Laboratory Assistant, starting September 15, 2025. See below for further details on the role and responsibilities 👇👇👇👇👇👇👇👇👇👇👇👇👇👇👇👇👇👇👇👇👇

It was an honor and a real pleasure to be the first speaker at the inaugural @bitsinbio.bsky.social meetup in Berlin!A fantastic opportunity to share my past work and future research directions with such an inspiring and engaged audience! Huge thanks to @instadeep.bsky.social for making it happen!

Just back from the Jacques Monod Conference on Membrane Remodeling in Roscoff—an inspiring trip for Sebastian Schuck and Michael Meinecke (@meineckelab)! We had exciting science, engaged in inspiring discussions, and enjoyed the stunning setting. There’s nothing quite like membrane research.

The Schuck lab is looking for a PhD student or postdoc who is keen to understand how cells control organelle size and shape. For more information, please visit www.bzh.uni-heidelberg.de/schuck and have a look at 'open positions’.

🚨 Lipid Time! 🚨 Excited to share our latest story now on @biorxiv-biochem.bsky.social ! Our brilliant PhD student @manpreet0700.bsky.social , together with @walter-nickel-bzh.bsky.social and myself, shows how PI(4,5)P₂ asymmetry in the plasma membrane drives the unconventional secretion of FGF2! 👇👇👇

Plasma membrane transbilayer asymmetry of PI(4,5)P2 drives unconventional secretion of Fibroblast Growth Factor 2

Unconventional secretion of Fibroblast Growth Factor 2 (FGF2) is based upon direct self-translocation across the plasma membrane, a process that involves the transient formation of a lipidic membrane ...

biorxiv.org

Lovely start into our new #SFB1638 on cellular membrane remodeling with a two-day kick-off meeting at the International Academic Forum Heidelberg (IWH). Many thanks to our speaker @meineckelab.bsky.social and team for the great organization.

🚨Another #PostDocOpportunity through the @hlsalliance.bsky.social program at our institute, in the junior research group led by @fabiololicato.com #LipidTime @uniheidelberg.bsky.social

Health + Life Science Alliance Heidelberg Mannheim @hlsalliance.bsky.social · last yr.

#PostDocCalls Project #85: ˚⋆🔬Lipid-Mediated Regulation of CD95 #Oligomerization and Signaling🧪🥽🧠⋆˚ Applications on the Alliance website: www.health-life-sciences.de/opportunitie... @dkfz.bsky.social @fabiololicato.com @bzh-hd.bsky.social @hlsalliance.bsky.social #LipidTime #ProteinDesign

👇👇👇👇👇👇

Fabio Lolicato@fabiololicato.com · last yr.

🚨 Postdoc Opportunity 🚨 Are you passionate about protein design and lipid interactions? Do you want to explore cutting-edge computational and biophysical approaches to understand these systems? Join our research group at @bzh-hd.bsky.social @hlsalliance.bsky.social #LipidTime

🚨 We are hiring 🚨 We seek to fill a full-time teaching position starting September 1, 2025! We look forward to your application (cover letter, CV, certificates, etc.) in a single PDF. Deadline: March 14, 2025 @uniheidelberg.bsky.social @bzh-hd.bsky.social 👇👇👇👇👇👇👇

🚨We are on Bluesky🚨 Hello World! Finally, the Heidelberg University Biochemistry Center (BZH) is on Social Media! Follow us for research updates, discoveries, and lab highlights! 🔬🧪🧑‍🔬👩‍🔬