Currently recruiting for our study of #perimenopause! We want to model how the dynamic hormone shifts of this period impact brain circuitry and, potentially, put a subset of women at greater risk of #alzheimers disease. This project funded by @yalebiomedimaging.bsky.social @whryale.bsky.social.
Carolyn Fredericks
@carolynfredericks.bsky.social
Asst Prof of Neurology at Yale. Our lab studies vulnerability & heterogeneity in neurodegeneration (esp AD & asyn) with an emphasis on multimodal neuroimaging. Mom to two little boys and one big dog. Baker, backpacker, devourer of books.
🚨The OMB rule will be the end of science as we know it. MARK YOU CALENDAR for the @standupforscience.net EMERGENCY SCIENCE MEETING June 2nd, 4pm et. We will be giving an overview & assigning EVERY SCIENTIST IN AMERICA their marching orders. REGISTER: events.standupforscience.net/stand-up-for...
Emergency Science Meeting by Stand Up for Science
[discussing OMB-2026-0034?]
events.standupforscience.net
new review paper in press, on a brand-new line of research that's personal for me and that I'm excited about — music in Alzheimer's disease and other dementias this one led by a wonderful student Sophia Moret and in collab with my kickass Yale Neurology colleague @carolynfredericks.bsky.social
Musicality is preserved in neurodegeneration: https://osf.io/rzju5
this ends with a description of what YOU can do. Please get involved now. Everyone can take one of these actions.
“The Senate Committee on Appropriations is scheduled to release its proposal for NIH’s 2026 budget later this week…The committee could include language that would prohibit the multiyear funding plan or extend the timeline for the transition.”🧪
New Science story about multi-year funding and it potential catastrophic consequences www.science.org/content/arti... 1/n
What a damn shame. And let's be clear: this rescissions package was merely a test. A start. 🧪 Science folks: Expect a similar bill coming soon for codifying cuts to this year's budget for NSF, NIH, etc. 🧵 Brief thread 1/3
Breaking News: The Senate approved a White House request to cancel $9 billion for foreign aid and public broadcasting. The House is expected to pass the bill.
Hamid Abuwarda's paper showing that we can use the functional connectome to predict focal tau binding in preclinical Alzheimer's disease is out today! academic.oup.com/braincomms/a...
Whole-brain functional connectivity predicts regional tau PET in preclinical Alzheimer’s disease
Abuwarda et al. demonstrate that whole brain functional connectivity predicts regional tau tracer binding in preclinical Alzheimer's disease. Their models
academic.oup.com
Great interview with Jenna Norton, one of the authors of the #BethesdaDeclaration about its origins and future art19.com/shows/federa... While you are here, sign the support letter (if you haven't already) and share this link. act.standupforscience.net/forms/add-na...
ADD YOUR NAME: Sign the Open Letter in Support of NIH Staff
Join the courageous and committed National Institutes of Health (NIH) public servants by adding your name now.
act.standupforscience.net
We miss you, Ben
#AltPride #AltGov To close out Pride Month, we are recognizing neuroscientist Ben Barres. Beyond making seminal discoveries related to glial cell function, he was also a staunch advocate for equality in science for both women and the LGBTQIA+ community. 1/n www.nature.com/articles/d41...
Now is a good time to sign on in support of the courageous folks at EPA who stood up for all of us. www.standupforscience.net/epa-declarat...
Support EPA Staff Now! — STAND UP FOR SCIENCE
Your solidarity with the EPA heroes increases the pressure on their Administrator Lee Zeldin.
standupforscience.net
@repbarragan.bsky.social Thank you so much for your forceful questioning (www.themirror.com/news/us-news... ) of RFK, Jr. It appears that many Alzheimer's Disease Research Center grants are now funded about months of delay. #CallingThemOutMatters
RFK called out over Alzheimer's move in tense exchange with Congresswoman
Rep. Nanette Barragán called out Robert F. Kennedy Jr. following cuts to Alzheimer's research, but the Secretary of the Department of Health and Human Services wasn't aware of them
themirror.com
It’s fine to call Collins or Murkowski. But it is much much much much much more impactful if you can get on local TV in their states and call them to vote against. And if you can’t do that, make a social media video. Communicating to their constituents he is better than calling them.
It is certainly worth calling Collins and Murkowski to tell them to vote no now that defunding Planned Parenthood made it in over their objections
🚨 Postdoc Opportunity!!! The Toronto Early Cognition Lab (@UofT) is hiring a postdoc to study early optimism in infants & young children. Work w/ multi-method approach, amazing undergrads & grads. Start: Fall 2025 or later. Details: jessica.sommerville@utoronto.ca RTs appreciated 💫
Earlier today, AAAS CEO Sudip Parikh testified as a bipartisan witness before the U.S. Senate Appropriations Committee, warning that without immediate action, the U.S. runs the risk of losing its position as a global leader in biomedical research and innovation.
"President Donald Trump says he wants to reduce our trade deficit. Yet he’s destroying one of our winningest exports: higher education" www.washingtonpost.com/opinions/202...
🧪Trump wants to cut NIH spending by 40%. If enacted, this will drive a massive, generational brain 🧠 drain of talented scientists and physician-scientists out of the US. Congress still controls the budget (for now). Call your reps and senators: (202) 224-3121 www.statnews.com/2025/04/16/t...
Trump budget draft proposes NIH consolidation and 40% spending cut
Draft Trump budget proposes a $20 billion NIH budget cut in 2026 and a sweeping consolidation
statnews.com
An update to show the seismic crash in NIH funding. The left side shows NIH has issued almost no "new" awards since Trump took office. Even renewals (you receive a 5 year award, but each year they renew it), which should be mushed into the lines above it, is shockingly low.
The trope that universities are "dependent" on the federal government fundamentally misunderstands how vital this partnership has been for the US. The private sector can't replace it. If we kill it, we're all worse off. From @donmoyn.bsky.social and me: donmoynihan.substack.com/p/are-univer...
As of this morning, the @aacu.org statement opposing the Trump admin's "unprecedented government overreach" has been signed by more than 400 #HigherEd leaders.
A Call for Constructive Engagement | AAC&U
A Call for Constructive Engagement
aacu.org
The notice and COMMENT PERIOD OPENED TODAY AND CLOSES MAY 23. Anyone who would like to register an objection or comment should go to this page and click on the green “public comment” button at the top: www.federalregister.gov/documents/20... 6/n
Improving Performance, Accountability and Responsiveness in the Civil Service
The Office of Personnel Management (OPM) is proposing a rule to increase career employee accountability. Agency supervisors report great difficulty removing employees for poor performance or misconduc...
federalregister.gov
ACTION ITEM-----ACTION ITEM Implementation of Schedule F This is what a lot of us have been worried about. This allows for many civil service positions to replaced with political appointees. This could include NIH institute directors and even POs. BUT THERE IS A COMMENT PERIOD... 1/n
the word alert is in a purple circle
ALT: the word alert is in a purple circle
media.tenor.com
🧪 www.statnews.com/2025/04/23/n... The beginning, I presume, of the Trump Administration's attempt to force journals to accept some number of alternative-view "research" articles on topics like vaccines causing autism or IV bleach injections to treat Covid (as suggested by our president in 2021).
New England Journal of Medicine gets swept up in U.S. attorney inquiry into alleged bias
Last week, at least one scientific journal received a letter from a top U.S. attorney asking it to respond to alleged bias. Now, NEJM has received a similar inquiry as well.
statnews.com
Updating dashboard this morning with new funding curves, the Barron's article (in Miscellaneous), and Excel files with the latest terminated grants (from the HHS TAGGS site). Looking at the latest terminated grants list was "interesting"... jeremymberg.github.io/jeremyberg.g... 1/n
NIH_since_1_20_25
jeremymberg.github.io
Really good point. These are cuts to research into cures for cancer and Alzheimer’s. And Trump is doing them to corrupt universities and end free speech and free thought. They want to force in conservative ideas that have lost in a free marketplace, and use cancer money to do that
I do wish big-time media orgs would stop taking the bait of calling these cuts to "Brown" or "Harvard." These are cuts to alzheimers research, maternal health research, antiviral coronavirus innovations, not "insert school here." They are cuts to our medical future and scientific livelihood.
The Trump administration is "willing to not just slash and burn research that challenges their political ideology but to replace it with shoddy studies designed to support their goals, under the guise of scientific legitimacy," Katherine J. Wu writes.
‘This Is Not How We Do Science, Ever’
The Trump administration is manipulating government-sponsored research to get the answers it wants.
bit.ly
More, or should I say, less pain at NIH... Dismemberment of the Office of Pain Policy and Planning office www.statnews.com/2025/04/08/n...
Unique pain research office eliminated in HHS purge
Pain is the most costly chronic health problem in the U.S. In latest RIFs at NIH, an entire division devoted to pain research was closed down.
statnews.com
There is a reason that private industry hires communications and government relations professionals. Want to make impactful change? Use every tool at your disposal, or partner with people/orgs who have these skills. I promise you every mid-level trade association is doing the same.
This sucks, but also means if you want coverage, contact your paper in advance of an action. Give them quotes. Send them to folks to interview. We did this for the NOAA protests and got wall to wall coverage for a week, with frontpages, opeds, and followups.
Firings at Federal Health Agencies Decimate Offices That Release Public Records “What we need to be doing is the opposite of what’s happening now: hiring more staff.” kffhealthnews.org/news/article...
Firings at Federal Health Agencies Decimate Offices That Release Public Records - KFF Health News
The Department of Health and Human Services’ mass firings included people who fulfill Freedom of Information Act requests for the Centers for Disease Control and Prevention, National Institutes of Hea...
kffhealthnews.org
We have slots for 2-3 postbacs! Get in touch if you’re interested in joining the Affective Neuroscience and Pain lab & contributing to our studies of pain, emotion, and social processing in the 🧠
Recruitment of postbacs & postdocs in the NIH IRP has resumed. I have no additional info beyond what is publicly stated on the website. www.training.nih.gov/research-tra...
DOGE-induced delays in trials at the NIH Clinical Center (Dr. Steve) Rosenberg said. “Right now, assuming things don’t get any worse, it would be a month [delay]. These are not patients that have very many months left.” This seemed inevitable but is still a big deal... wapo.st/4j8Hwd1 (Gift link)
NIH scientists have a cancer breakthrough. Layoffs are delaying it.
A big step forward in cancer therapy has been slowed by layoffs and new restrictions at the National Institutes of Health, where it was developed.
wapo.st
Happy World Health Day! Doctors for America pledges to continue our mission of educating and empowering doctors and healthcare advocates to lead initiatives that improve the health of patients, communities, and the nation.