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Executive Summary of State-of-the-Art Review: Modern Approach to Nocardiosis—Diagnosis, Management, and Uncertainties ⭐ Editor's Choice #IDSky

Executive Summary of State-of-the-Art Review: Modern Approach to Nocardiosis—Diagnosis, Management, and Uncertainties

Nocardia is a genus of gram-positive, partially acid-fast bacilli that typically infect people with chronic lung disease or immunocompromised states.

academic.oup.com

🆕💫 Narrative review in ICM How to approach a patient hospitalized for pneumonia who is not responding to treatment? #idsky #EMIMCC link.springer.com/article/10.1...

What I wish I had right now, an already made newsletter on "Things We Do For No Reason: 'Continue IV Antibiotics While Inpatient, Then Discharge Home on Oral Antibiotics'" in patients that can otherwise tolerate oral therapy. Fewer lines, shorter stays, same outcomes. #IDSky #PharmSky

For institutions that have sulbactam-durlobactam on formulary. What are your criteria for use? Do you use it first line for all CRABs? Has it replaced high dose ampicillin-sulbactam? #IDSky #Pharmsky

Important article for #AMSSky, #TxID, #UTISky, and #IDSky in @cidjournal.bsky.social: In neutropenic & non-neutropenic cancer patients w/ & w/o catheters, the absence of nitrite/leukocyte esterase or WBC<10 had high NPV for clinically significant bacteriuria academic.oup.com/cid/advance-...

#IDSky #PharmSky Patient with M. abscessus bacteremia on iHD. 1. How are you dosing amikacin in these patients? 2. Do you have specific peak goals? 3. Do you omit amikacin entirely? If possible, you're willing to share protocols, that'd be extremely helpful!

Where do we go from here with UTI WikiGuidelines and what do you use? This study used cephalexin @ variable doses), median txt 10d, and cefazolin MIC of <=16 as susceptible. (CLSI cut-off for uUTI). Personally, I use cephalexin 1000 mg PO QID x10-14d if cefazolin MIC <=2 for pyelonephritis.

Antibiotic Steward 🅱️C🆔🅿️🌟@absteward.bsky.social · 2y ago

Oral cephalosporins for pyelonephritis?! 🆕️⚡️⚡️COPY-ED Multicenter, retrospective study N=851 No difference in 14-day pyelonephritis treatment failure for oral cephalosporins* vs FQ/TMP-SMX for outpatient pyelonephritis in the ED #idsky #medsky * Mostly cephalexin www.sciencedirect.com/science/arti...

#IDSky #PharmSky Pt w/ MTB on RIPE w/ rifampin 1200 mg QD (TDM ✅) Smear (+) x3 mo. Now with (+) serum galactomannan (0.5) and worsening O2 status. ID wants to treat for aspergillosis. Would you start posa and continue rifampin or convert to rifabutin and start posa?

Presented on ED abx stewardship to our new ED physician group. Highlighted our ASB treatment rates, educated on our UTI guidelines, and showed our compliance with STI screening with CDC recommendations. How do you engage your ED teams for abx stewardship? #IDsky #Pharmsky #Medsky

Does your ED use Dalbavancin for SSTi? If so, what's your experience like? Is it any different from Linezolid with re: patient experience/admission/readmission/relapse/recurrence? #IDsky

Hello #PharmSky #IDSky! I’m Chris, an ID pharmacist in San Diego, passionate about antimicrobial stewardship and resistance. Looking forward to connecting and learning with everyone here!