A new preprint out doi.org/10.64898/202... exploring the bioenergetics and metabolism of the bacterial pathogen Enterococcus faecalis with some very interesting results! Fantastic work from @olivia-paxie.bsky.social during her PhD!

Great treat to hear about @cbcb-newcastle.bsky.social history and great science from Jeff Errington #microsky

Great to have @carokobras.bsky.social presenting her work on #bacterial strategies against #beta-lactams part of @cbcb-newcastle.bsky.social celebration day!

Please share - full funded (UK students only) PhD studentship in the Duncan lab ‘intergrated ‘omics for accelerated antibtioic dicovery from abyssal actinomycetes’. Co-supervisors @thecopperdoctor.bsky.social, Marcel Jaspars, @zmaw.bsky.social- deadline 20th May www.findaphd.com/phds/project...

**PhD opportunity** Join me, @henrikstrahl.bsky.social, and Alistair Brown at @newcastleuni.bsky.social to uncover how Mycobacterium tuberculosis survives antibiotics, one molecule at a time! 🔬🦠 #PhD #microbiology #biophysics #microscopy 📅 Deadline 20 May 2026 (UK home only) RT = 🙏

Resolving the mechanism of Mycobacterium tuberculosis antibiotic tolerance through single-molecule microscopy at Newcastle University on FindAPhD.com

PhD Project - Resolving the mechanism of Mycobacterium tuberculosis antibiotic tolerance through single-molecule microscopy at Newcastle University, listed on FindAPhD.com

findaphd.com

We have a PhD studentship open! (UK only sadly) but if you are or know a student keen to work on some *really* weird mycobacterial enzymes then get in touch! #glycotime Advert below www.findaphd.com/phds/project...

Uncovering a new class of toxins in pathogenic mycobacteria at Newcastle University on FindAPhD.com

PhD Project - Uncovering a new class of toxins in pathogenic mycobacteria at Newcastle University, listed on FindAPhD.com

findaphd.com

Want to research the basis of how drug resistant bacteria interact with human immune cells? Fully funded 4-year PhD position available (UK home students). Come and join our amazing interdisciplinary team at the intersection of microbiology, immunity, metabolism and the clinic! Please spread the word

Hiding in plain sight: How a multi-drug resistant pathogen evades detection and killing by human neutrophils at Newcastle University on FindAPhD.com

PhD Project - Hiding in plain sight: How a multi-drug resistant pathogen evades detection and killing by human neutrophils at Newcastle University, listed on FindAPhD.com

findaphd.com

🧫 #AMR #PhD open @newcastleuni.bsky.social! How does #Cdifficile protein "armour" help it resist antimicrobials? Join me and @henrikstrahl.bsky.social to find out using: 🔬 #Structuralbiology, #microbiology #microscopy #genetics 📅 Deadline 20 May 2026 #PhD #PhDLife Pls share! (UK home only)

C. difficile S-layer’s role in antimicrobial resistance at Newcastle University on FindAPhD.com

PhD Project - C. difficile S-layer’s role in antimicrobial resistance at Newcastle University, listed on FindAPhD.com

findaphd.com

What are the genetic and molecular determinants underpinning the repair of bidirectional replication fork collapse in bacteria? PhD position open in my lab in collaboration with the brilliant @heathmurraylab.bsky.social. Please share and contact me if interested: www.findaphd.com/phds/project...

Identifying bacterial DNA repair requirements enabling stable genetic inheritance during bidirectional replication fork collapse at Newcastle University on FindAPhD.com

PhD Project - Identifying bacterial DNA repair requirements enabling stable genetic inheritance during bidirectional replication fork collapse at Newcastle University, listed on FindAPhD.com

findaphd.com

Big congratulations, Marwa Sayed Ahmed (Richard Daniel's lab), for a successful PhD defence! Also, thanks to @gingermicrobe.bsky.social and David Bolam for the examination.

Check out our new preprint providing direct in vivo evidence for transertion in Bacillus subtilis (also arguing for coupled transcription-translation). Excellent work by Jonathan Norris, co-supervised by Nikolay Zenkin and me during his PhD. www.biorxiv.org/content/10.6... #microsky

It's been our great pleasure to host @lalouxlab.bsky.social for a seminar today, and we thoroughly enjoyed learning about Bdellovibrio polarity and polar protein targeting. Such an odd little bacterium!

Very happy to host Fred Antson (University of York) today for a seminar! Stunning structures and functional insights into phage/virus capsids and DNA loading.

www.nature.com/articles/s41...

Mechanism and reconstitution of circadian transcription in cyanobacteria - Nature Structural & Molecular Biology

Fang et al. reveal how a bacterial circadian clock turns genes on and off at the right times of day and use the purified proteins to drive circadian gene transcription in a test tube for days.

nature.com

Fabian was quicker :) But yes, we have an open postdoc position in bacterial bioenergetics and membrane biology, using on B. subtilis as the model. Come join us! @cbcb-newcastle.bsky.social is a great place to work, and we are a friendly, international lab. Visa+IHS fees covered. #microsky

Molecular Microbiology@molmicrounihoh.bsky.social · 8mo ago

PostDoc position in Newcastle upon Tyne: @henrikstrahl.bsky.social

Happy holidays everyone from a not very wintry Newcastle!

Congratulations Laura, the latest CBCB PhD graduate heading for a science career!

Prof Paula Salgado@pssalgado.bsky.social · 10mo ago

It was a pleasure to be an examiner of the latest @henrikstrahl.bsky.social PhD graduate Laura Dobby. Great work and a very nice discussion in her viva. Congratulations Dr Dobby! @cbcb-newcastle.bsky.social

Today, we are lucky to have Imane El Meouche from IAME, France to give a MCM seminar @medicalsciencesncl.bsky.social (chaired by @henrikstrahl.bsky.social) on antibiotics tolerance in E. Coli

Big congratulations Neha!

Neha Ramchandani@neharamchandani.bsky.social · 10mo ago

I had a great time at the @bsacandjac.bsky.social ARM workshop! I met some wonderful scientists and had great discussions about my work! Also, I walked away with a poster prize!! Thanks for organising @friendlymicrobe.bsky.social @conmeehan.bsky.social

Now properly published at @natcomms.nature.com with few additional experiments incl. demonstration of Daptomycin's ability to depolarise non-growing cells. See the original preprint-thread for a summary of our findings. www.nature.com/articles/s41... #microsky

The last resort antibiotic daptomycin exhibits two independent antibacterial mechanisms of action - Nature Communications

The precise mechanism of action of the antibiotic daptomycin is controversial. Here, Buttress et al. provide evidence for two independent antibacterial mechanisms: membrane depolarisation and inhibiti...

nature.com

Dr Jess Buttress@jbuttresssci.bsky.social · 2y ago

So happy our pre-print on daptomycin mechanism of action is now out! Here, we present three main findings: i) daptomycin does not form large membrane pores in either B. subtilis or S. aureus, (1/3)

Looking for a PhD opportunity in Microbiology? Consider joining one of the UK's leading microbiology research clusters at Newcastle University. See the thread for MRC DTP studentships currently advertised. @medicalsciencesncl.bsky.social @sagencl.bsky.social @cbcb-newcastle.bsky.social #microsky

You were already one of us. Now just under the same roof!

Prof Paula Salgado@pssalgado.bsky.social · 11mo ago

The #SalgadoLab has now officially moved into @cbcb-newcastle.bsky.social! Thank you to amazing lab members Anna, Ella and Pavi for making it happen and @henrikstrahl.bsky.social Kasia, Charles, Tom, Amandeep, Julie and everyone at CBCB! Looking forward to working closely with everyone! #microsky

How do SMC complexes load onto DNA to get ready for loop extrusion? @roisnehamelinf.bsky.social & co discovered that Wadjet, an SMC complex involved in bacterial DNA immunity, performs some impressive molecular gymnastics 🤸‍♂️🤸‍♂️🤸‍♂️. Check out the new paper: www.cell.com/molecular-ce...

It was great to have Mark visit us today. Many great science discussions and hopefully new collaborations to start!

Dr Katherine Duncan@kateduncan.bsky.social · 12mo ago

Very exciting to have Prof Mark Blaskovich @medicalsciencesncl.bsky.social (hosted by @henrikstrahl.bsky.social) all the way from the University of Queensland, Australia to give a seminar on collaborative approaches to combat antimicrobial resistance #drugdiscovery #AMR #antibiotics

A new methods paper from us, this time with a focus on reliable monitoring membrane potential and cell lysis at different growth stages and cell densities. Also, note the surprisingly high level of background lysis in seemingly healthy B. subtilis cultures. www.biorxiv.org/content/10.1...

Monitoring single cell bioenergetic status and cell lysis in dense and differentiating Bacillus subtilis cultures

Bacillus subtilis is a major model organism for studying population heterogeneity in clonal bacterial cultures due to its high genetic tractability and ability to differentiate into subpopulations wit...

biorxiv.org

Fascinating seminar by Prof @gebhardlab.bsky.social on ‘Building bacterial bridges – How an ancient bacterial trait can help us build the infrastructure of the future’ and visit at @cbcb-newcastle.bsky.social (hosted by @henrikstrahl.bsky.social) #bacillus #spores

Don’t miss your chance #Newcastle, tickets for #PINT25 are out! @pintofscience.uk @pintsworld.bsky.social More info for venues and tickets here pintofscience.co.uk/events/newca... Repost appreciated :)

Looking for a PhD opportunity in Microbiology? Consider joining one of the strongest clusters of microbiology research in UK at @newcastleuni.bsky.social, Biosciences Institute, and @cbcb-newcastle.bsky.social. See thread for BBSRC DTP PhD studentships currently advertised.

Congratulations Charles! It's a great paper!

Charles Winterhalter@winterhalterlab.bsky.social · 2y ago

Excited to share with you the story that enabled me to start my own lab: what happens when the bacterial DNA replication machinery encounters single-strand discontinuities on template DNA? What is required for break repair and replication restart? www.biorxiv.org/content/10.1...

Excited to share with you the story that enabled me to start my own lab: what happens when the bacterial DNA replication machinery encounters single-strand discontinuities on template DNA? What is required for break repair and replication restart? www.biorxiv.org/content/10.1...

Rescuing bacterial genome replication: essential functions to repair a double-strand break and restart DNA synthesis

Many antibiotics indirectly generate reactive oxygen species (ROS) that can damage bacterial genomes. Oxidised nucleobases become genotoxic when they are targeted for repair through excision, generati...

biorxiv.org