CERM/CIRMMP Infrastructure
@cerm-cirmmp.bsky.social
CERM/CIRMMP is a NMR infrastructure for Life Sciences, which provides a unique environment for research in the field of Structural Biology. https://www.cerm.unifi.it/
Tomorrow, @dr-ryan-ellison.bsky.social of @instruct-eric.bsky.social will be representing the FHERITALE consortium at the Mnp6 Microplastics conference in Birmingham! We will also have a poster presentation. Please come and speak to Ryan with any questions you may have!
We are happy to be attending #MNP26 at the University of Birmingham today. If you have any questions about the FHERITALE project, please come and speak to us at poster number 1!
It was great to connect with many scientists at the poster session yesterday at #MNP26 at the University of Birmingham! On to Day 2 and another great selection of talks!
Recent paper by Luo et al. in the @rsc.org journal @analyticalmethods.rsc.org . They developed a simple method for quantifying #microplastics in water using adsorption of hydrophobic dyes, combined with ultraviolet-visible spectrophotometry.
A simple method for quantifying microplastics in water utilizing hydrophobic dyes via ultraviolet-visible spectrophotometry - PubMed
Polystyrene microplastics have emerged as a global environmental concern due to their widespread distribution and potential risks to ecosystems and human health. Accurate quantification of…
pubmed.ncbi.nlm.nih.gov
The 18th Florence Award for Molecular Sciences celebrated excellence in scientific research by honoring Søren Brunak (Københavns Universitet - University of Copenhagen), one of the pioneers in applying #ArtificialIntelligence and #MachineLearning to medicine!
Happening today! At 15:00 CET you can hear from expert speakers about the latest methods in spectroscopic detection of micro- and nanoplastics, as well as upcoming research projects! For more information and to register, see here:
Microsoft Virtual Events Powered by Teams
Microsoft Virtual Events Powered by Teams
events.teams.microsoft.com
Happening now! FHERITALE webinar 4! You can still join here: events.teams.microsoft.com/event/6f2c70...
Thank you to our project partners: @cerm-cirmmp.bsky.social @instruct-eric.bsky.social @cnb-csic.bsky.social @anaeeeric.bsky.social METROFOOD-RI @eirene-ri.bsky.social
Some highlights from the training course hosted by #NIRI, organized in collaboration with the #MRLATVIA project and @instruct-eric.bsky.social . An opportunity to exchange knowledge and gain practical experience in #NMR, #AI, #solid-state methods, and #hyperpolarization
Join us on June 15 at 15:00 CET for the next FHERITALE webinar: “Spectroscopic approaches to microplastics detection”. You can register for the webinar here: events.teams.microsoft.com/event/6f2c70...
From the Instruct-ERIC Biennial Structural Biology Conference 2026 in Brussels: CERM/CIRMMP and @fheritale.bsky.social are pleased to be part of this stimulating international environment for collaboration and innovation. @instruct-eric.bsky.social
CERM/CIRMMP Infrastructure was pleased to take part in the FHERITALE Stakeholder Meeting hosted by Sciensano in Brussels, focused on strengthening European Research Infrastructure synergies on micro- and nanoplastics research!
Today @instruct-eric.bsky.social is @fheritale.bsky.social stakeholders meeting in Brussels. We will be discussing how the existing infrastructures can tackle challenges caused by artificial materials It's key to use what we already have and identify what is still needed @cerm-cirmmp.bsky.social
A great group today at the FHERITALE Stakeholder Meeting! Thank you to everyone for rich and informative discussions, and thank you to hosts @sciensano.be and organisers @cerm-cirmmp.bsky.social
It was an honour to welcome Dr. Yogesh Gupta back to CERM/CIRMMP today. There is no greater pride for our institute than seeing a former PhD student return as a distinguished scientist in his field! #NMR#StructuralBiology#science
This Month, we caught up with Antonio Rosato of @cerm-cirmmp.bsky.social, about the work of his group on “Master of Metals 2”, an accessible tool that can predict metal binding sites for zinc ions in proteins! instruct-eric.org/scientifichi...
Machine Learning to predict zinc metal ion binding sites in proteins: Master of Metals2
Instruct-ERIC is a pan-European research infrastructure in structural biology, making high-end technologies and methods available to all European researchers.
instruct-eric.org
We are hosting a Stakeholder meeting in Brussels on 26 May! This will bring together research infrastructures, policymakers and industry partners to discuss the impact of micro- and nano-plastics on food, health, and the environment! Sign up here: docs.google.com/forms/d/e/1F...
The programme will include a keynote lecture, interactive roundtables, and a session on the current state of the art and research gaps, with a focus on identifying priorities for future action.
Contributors include @eurobioimaging.bsky.social, CSIL, National Research Council of Italy, EU Food Safety Platform, @ec.europa.eu , @embrc.eu, MIRRI ERIC, @cefic.bsky.social, National Hellenic research foundation, PARC, @instruct-eric.bsky.social , Barilla Group, and METROFOOD-IT.
Live with the 46th Structure Meets Function webinar by @instruct-eric.bsky.social The session brings together two speakers who have accessed multiple services offered through the #ITACA.SB project 👇 Sharon Spizzichino, Sapienza Rome University Mariapina D'Onofrio, Verona University
Are you interested in these topics? The @fheritale.bsky.social consortium invites stakeholders from across the research landscape to join us: 📍 Brussels 🗓️ 26 May. Researchers, industry, and policymakers are welcome to contribute! For more information: fheritale.eu/stakeholder-...
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FHERITALE@fheritale.bsky.social · 4mo agoOn #WorldHealthDay, we want to highlight the potential impact of micro and nanoplastics on human health via inflammation, oxidative stress, and the delivery of toxic chemicals or pathogens. For a comprehensive overview, see our Strategic technology and service needs: zenodo.org/records/1938...
New insights into α-synuclein interactions via NMR & MD, supported by @instruct-eric.bsky.social and #ITACA.SB! Read the full article here 👇
Molecular Interplay of Small Molecules and Calcium Ions with α-Synuclein Revealed by NMR and Molecular Dynamics Simulations
Human α-synuclein is an intrinsically disordered protein concentrated at presynaptic terminals and strongly linked to Parkinson’s disease and other synucleinopathies. Its dynamic C-terminal region mediates interactions with small molecules and metal ions. Here, we used high-resolution nuclear magnetic resonance spectroscopy (NMR) and molecular dynamics (MD) simulations to characterize interactions between the C-terminal α-synuclein construct, the small molecule fasudil, and calcium ions. NMR data show that fasudil and Ca2+ bind preferentially to overlapping regions enriched in alternating tyrosine and acidic residues while preserving the protein’s disordered nature. Side-chain-resolved spectra indicate distinct driving forces for fasudil and calcium binding. MD simulations reveal that Ca2+ modifies the local electrostatic environment, decreasing fasudil interaction frequency through electrostatic screening and steric effects. Despite this, fasudil retains dynamic, reversible contacts with key tyrosine residues. Overall, exposed α-synuclein conformations allow simultaneous, ligand-specific interactions, highlighting side-chain hotspots governing binding in Ca2+-rich conditions.
pubs.acs.org
On this @who.int #WorldHealthDay we would like to showcase work from Instruct-IT and @cerm-cirmmp.bsky.social, showing how structural biology research contributes to development of new medicines and understanding of disease. Full webinar available via our YouTube Channel:
Structure Meets Function Webinar 42 | Instruct-IT
The latest webinar in the Instruct-ERIC Structure Meets Function series this month includes speakers who have accessed cutting-edge structural biology services through Instruct. The webinar series…
youtu.be
The latest deliverable from the FHERITALE project is here, produced in collaboration with @sciensano.be ! We identified strategic technology and service needs by taking advantage of state-of-the-art AI technologies. You can download this deliverable here: zenodo.org/records/1938...
Notes from last week’s CanSERV Annual Meeting @instruct-eric.bsky.social Strong scientific contributions from Robert Konrat and Marco Schiavina. They both applied #NMR here ar @cerm-cirmmp.bsky.social , within the #CanSERV framework, to investigate BRCA1 interactions in biomolecular complexes
The @fheritale.bsky.social consortium is bringing together stakeholders across the research landscape to address this question in a dedicated event in Brussels, 26 May. 🔸 For further information 👉 lnkd.in/dGy2J_AB 🔸Interested in participating? lnkd.in/dHqJM9E3
New article from #UNIFIMAGAZINE showcases the outcomes of the #ITACA.SB project, which has strengthened technological platforms and expanded access to high-level scientific services. @instruct-eric.bsky.social www.unifimagazine.it/biologia-str...
Biologia strutturale: infrastrutture e tecnologie d’eccellenza sempre più accessibili - Unifimagazine - La testata online dell’Ateneo fiorentino
I risultati del progetto ITACA.SB, condotto dall’Ateneo fiorentino e dal Consiglio Nazionale delle Ricerche con un finanziamento PNRR da 18 milioni
unifimagazine.it
New paper out in @chemicalscience.rsc.org: doi.org/10.1039/D5SC... Thanks to everyone involved, and in particular my colleagues at @cerm-cirmmp.bsky.social for the wonderful collaboration! (1/2)
The fine effects of high magnetic fields on hyperfine shifts
We report a comprehensive investigation of the magnetic field dependence of NMR hyperfine shifts in paramagnetic systems, a critical observable in the study of molecular magnetism. By combining high-f...
doi.org