Electrophysiology in nanoscale compartments rupress.org/jgp/article/... #IonChannels Interesting, but sorry $$$$$$

Evolution, hibernation, and inactivation of voltage-gated Na #ionchannels | Journal of General Physiology rupress.org/jgp/article/...

Model prokaryotic potassium channels: Predictive power and relevance to eukaryotic #ionchannels | Journal of General Physiology rupress.org/jgp/article/...

Differential regulation of β1-dependent voltage shifts and kinetic modulation by an extracellular glutamate in NaV1.6 VSDIV. New study by Maxime Lammens, Frank Bosmans et al. (Ghent University) rupress.org/jgp/article/... #IonChannels #Biophysics #MolecularPharmacology

📣 Call for Papers 📣 JGP welcomes submissions that focus on increasing our understanding of the role of voltage-gated sodium channels in the broad physiological and pathophysiological context. 👉 rupress.org/jgp/pages/ca... #IonChannels #CallForPapers #WSCC26

Piezo #ionchannels et al

Ritu Raman@rituraman.bsky.social · 3w ago

We can now steer blood vessels with dynamic forces and even re-direct vessels as they're growing! Great MIT News feature on our new paper in PNAS, outlining how a chance encounter with @ardemp.bskyverified.social helped us identify the role of PIEZO1 in this process: news.mit.edu/2026/mit-eng...

Kinetic reconstruction of graded membrane excitability in #Paramecium. New tudy from Takashi Tominaga and Yoko Tominaga (Tokushima Bunri University): rupress.org/jgp/article/... #CellularPhysiology

PV interneuron-targeted CRISPRa rescue of SCN1A haploinsufficiency in Dravet syndrome https://www.biorxiv.org/content/10.64898/2026.07.12.737793v1

Full article: mTORC2-Nav1.2 #ionchannel signaling drives early hyperexcitability in Alzheimer’s disease mouse model www.tandfonline.com/doi/full/10....

Gating shift to an ohmic mode of TREK-1 #ionchannel induced by docosahexaenoic acid: Biophysical Journal www.cell.com/biophysj/ful...

PIEZO #ionchannel Mechanotransduction in the Cardiovascular System: Physiological Roles and Disease Implications - Cardiovascular Science www.sciepublish.com/article/pii/...

If only there had been some clue. Editorial Note: Terahertz Irradiation Promotes Angiogenesis in vitro by Enhancing Permeability of the Voltage-Gated Calcium #IonChannel | PLOS One journals.plos.org/plosone/arti...

Full article: Role of TRPV4 #Ionchannels in high glucose-induced neurotoxicity in a neuronal-like cell model www.tandfonline.com/doi/full/10....

Differential regulation of β1-dependent voltage shifts and kinetic modulation by an extracellular glutamate in NaV1.6 #IonChannels VSDIV Journal of General Physiology $$$$$$ rupress.org/jgp/article/...

Mechanistic insights into DCPIB inhibition of VRAC anion #IonChannels: Electrostatic control and binding plasticity $$$$$$$$ rupress.org/jgp/article/...

An epilepsy-associated KV3.1 potassium #ionchannel variant acts via dominant-positive effect | Journal of General Physiology rupress.org/jgp/article/...

Structure-function analysis of the lithium-ion selectivity of the voltage-gated sodium #ionchannel | Journal of General Physiology rupress.org/jgp/article/...

Maxime Lammens, Frank Bosmans et al. show how an auxiliary β1 subunit tunes the activity of the human Na+ channel NaV1.6, a key regulator of electrical signaling in neurons, linking channel structure to mechanisms that shape neuronal excitability. rupress.org/jgp/article/... #IonChannels

Missense mutation causes multiple defects in Nav1.4 #ionchannel gating and leads to an SCN4A-associated overlap phenotype | Journal of General Physiology rupress.org/jgp/article/...

Bladder under stress: Pathological and adaptive shifts in #ionchannel expression www.tandfonline.com/doi/full/10....

Full article: Role for TREK-1 #ionchannels as a polymodal sensor and regulator of cell activity www.tandfonline.com/doi/full/10....

Full article: Quantitative analysis of trafficking defects induced by heterozygous expression of hERG #ionchannel voltage sensor domain variants www.tandfonline.com/doi/full/10....

Calmodulinopathy variants impair CaV1.3 and CaV2.1 #IonChannel regulation | Journal of General Physiology $$$$$$ rupress.org/jgp/article/...

Cav3.2 T‐type calcium #Ionchannels in chronic pain: Structural insights, pharmacological advances and challenges in subtype selectivity - Lu - British Journal of Pharmacology bpspubs.onlinelibrary.wiley.com/doi/10.1111/...

Structural evidence that a lipid plug controls K2P6.1(TWIK-2) #IonChannel function | Nature Communications www.nature.com/articles/s41...

NMDA and glycine #IonChannel receptors provide dual presynaptic regulation on climbing fibre inputs to cerebellar Purkinje cells - Benton - 2026 - The Journal of Physiology physoc.onlinelibrary.wiley.com/doi/10.1113/...

Our paper is now online here: rdcu.be/fpILZ

A ratiometric fluorescent reporter of mitochondrial sodium

Nature Chemical Biology - A ratiometric fluorescent probe that maps absolute mitochondrial Na+ at single-organelle resolution and works independently of membrane potential has now been developed....

rdcu.be

Functional role of Nav1.8 channels in action potentials of mouse CGRP‐lineage dorsal root ganglion neurons - Osorno - The Journal of Physiology physoc.onlinelibrary.wiley.com/doi/10.1113/...

The endogenous cannabinoid system gates plasticity of tonic GABA #IonChannel inhibition - Colangeli - 2026 - The Journal of Physiology physoc.onlinelibrary.wiley.com/doi/10.1113/...

Will the real KATP please stand up? Kir6.2/SUR2A takes the stand in the tiring case of skeletal muscle fatigue | Journal of General Physiology rupress.org/jgp/article/...