So thankful to Mindy and Jon Gray of the Gray Foundation for the award to our lab for BRCA-Related Cancer Research! And a thank you to Wojciech Fendler from the Medical University of Lodz. www.businesswire.com/news/home/20...

Big congratulations to @susankilgas.bsky.social, who won a Poster Presentation Award at the 20th International p53 Workshop | p53 Conference, which took place last week in Toronto! Fantastic work! #p53biology @danafarber.bsky.social

Thank you for highlighting our work!

American Cancer Society@americancancersoc.bsky.social · 3mo ago

1. A new @cp-molcell.bsky.social paper from @chowdhurylab.bsky.social that shows proximal polyadenylation site (pPAS) within MRE11 sustains its transcription through promoter–PAS chromatin looping. ACS supported this work through Dr. Ke Cong's postdoc fellowship. doi.org/10.1016/j.mo...

Out today in @cp-molcell.bsky.social! We show that proximal polyadenylation site (pPAS) within MRE11 sustains its transcription through promoter–PAS chromatin looping. Congratulations to first author Kaimeng Huang, all co-authors and collaborators. www.sciencedirect.com/science/arti...

MRE11 proximal polyadenylation site-mediated looping impacts transcription and genomic stability

Alternative polyadenylation (APA) generates transcript isoforms with variable 3′ untranslated regions (UTR) lengths, yet its role in DNA damage respon…

sciencedirect.com

The Chowdhury Lab at the Dana-Farber Cancer Institute is hiring a Senior Research Technician! If you are passionate about NGS and its applications in cancer research, apply here: careers.dana-farber.org/job/650/seni...

Research Laboratory Job: Senior Research Technician- Chowdhury Lab at Dana-Farber Cancer Institute in 450 Brookline Ave, BOSTON, MA

Senior Research Technician- Chowdhury Lab job

careers.dana-farber.org

Excited to share that Michelle Swift has been selected as an OCRA grantee! This support will help us study mechanisms of PARP inhibitor resistance in ovarian cancer and identify new therapeutic opportunities. ocrahope.org/research/cur...

Congratulations to @chiaramasnovophd.bsky.social on receiving the @americancancersoc.bsky.social Postdoctoral Fellowship! 🎉 Her project will be defining the DNA Repair Independent Mitotic Role of 53BP1 Well deserved recognition of outstanding work!

Congratulations to @susankilgas.bsky.social on receiving the first place Best Poster Award at the DNA Damage Mutation and Cancer Gordon Research Conference for her poster on a novel layer of p53 regulation through TIRR 🎉

Congratulations to Michelle Swift on receiving the Best Short Talk Award at the #DRRSC26 Fusion Conference for her presentation on BRCA1/BARD1 regulation of DNA repair. 🎉 @fusionconf.bsky.social

Excited to share our new paper from the Buhrlage lab & Chowdhury labs! 🎉 We designed CAS-010, a selective, low nanomolar USP28 inhibitor that reduces p53 transcriptional activity, mimics p53 loss & disrupts 53BP1-USP28 binding, offering new insights into USP28 function. www.cell.com/cell-chemica...

Pharmacologic interrogation of USP28 cellular function in p53 signaling

Bratt, Kilgas et al. describe the SAR-driven design of CAS-010, a selective USP28 probe, alongside a control compound and an inhibitor-resistant mutant. They show that USP28 inhibition mimics p53 path...

cell.com

🧬 Calling grad students & postdocs in genome stability/oncology: don’t forget to register for the 2026 Gordon Research Seminar runs Feb 28–Mar 1, Ventura, CA. Keynote: @chowdhurylab.bsky.social. Abstracts due Nov 23, 2025. 🔗 Sign up here: www.grc.org/dna-damage-m...

Excited to share our latest publication, out in @science.org! We define a key role for the CST complex in double-strand break repair pathway choice. This study was conducted in close collaboration with the Sung lab at UT Health San Antonio. Congrats to @michelleswift.bsky.social and all authors!

CTC1-STN1-TEN1 controls DNA break repair pathway choice via DNA end resection blockade

Antagonistic activities of the 53BP1 axis and the tumor suppressor BRCA1-BARD1 determine whether DNA double-strand breaks (DSBs) are repaired by end joining or homologous recombination. We show that t...

science.org

Thank you to @chowdhurylab.bsky.social (@danafarber.bsky.social) for joining us for a fantastic #WednedsayLectureSeries on "DNA repair mechanisms in the context of cell cycle with implication in #cancer." 🧬 Hosted by the Si Lab. #SciSky #ResearchSky

A huge thank you to our speakers @kajastelab.bsky.social and Raphael Ceccaldi for their amazing talks and fascinating research at yesterday's webinar! Our next webinar is on June 3rd featuring @agagambus.bsky.social and @chowdhurylab.bsky.social. Join our community: docs.google.com/forms/d/e/1F...