Big congratulations to @susankilgas.bsky.social, who won a Poster Presentation Award at the 20th International p53 Workshop | p53 Conference, which took place last week in Toronto! Fantastic work! #p53biology @danafarber.bsky.social

Congratulations to @susankilgas.bsky.social on receiving the first place Best Poster Award at the DNA Damage Mutation and Cancer Gordon Research Conference for her poster on a novel layer of p53 regulation through TIRR 🎉

Congratulations @susankilgas.bsky.social — not only a great scientist, also a great communicator of science!!!

Chowdhury Lab@chowdhurylab.bsky.social · 6mo ago

Congratulations to @susankilgas.bsky.social on receiving the first place Best Poster Award at the DNA Damage Mutation and Cancer Gordon Research Conference for her poster on a novel layer of p53 regulation through TIRR 🎉

Trainees in genome stability 🧬: There’s still time to register for the 2026 Gordon Research Seminar (Feb 28–Mar 1, 2026)! Poster & talk abstracts accepted until Dec 30, 2025. Huge thanks to our supporters: Pfizer, The Company of Biologists, CST & the Karlseder Lab. www.grc.org/dna-damage-m...

A reminder to register for the 2026 GRS meeting taking place from Feb 28-Mar 1 in Ventura, CA!

Susan Kilgas@susankilgas.bsky.social · last yr.

🧬 Calling grad students & postdocs in genome stability/oncology: don’t forget to register for the 2026 Gordon Research Seminar runs Feb 28–Mar 1, Ventura, CA. Keynote: @chowdhurylab.bsky.social. Abstracts due Nov 23, 2025. 🔗 Sign up here: www.grc.org/dna-damage-m...

Excited to share our new paper from the Buhrlage lab & Chowdhury labs! 🎉 We designed CAS-010, a selective, low nanomolar USP28 inhibitor that reduces p53 transcriptional activity, mimics p53 loss & disrupts 53BP1-USP28 binding, offering new insights into USP28 function. www.cell.com/cell-chemica...

Pharmacologic interrogation of USP28 cellular function in p53 signaling

Bratt, Kilgas et al. describe the SAR-driven design of CAS-010, a selective USP28 probe, alongside a control compound and an inhibitor-resistant mutant. They show that USP28 inhibition mimics p53 path...

cell.com

🧬 Calling grad students & postdocs in genome stability/oncology: don’t forget to register for the 2026 Gordon Research Seminar runs Feb 28–Mar 1, Ventura, CA. Keynote: @chowdhurylab.bsky.social. Abstracts due Nov 23, 2025. 🔗 Sign up here: www.grc.org/dna-damage-m...

Thank you to @chowdhurylab.bsky.social (@danafarber.bsky.social) for joining us for a fantastic #WednedsayLectureSeries on "DNA repair mechanisms in the context of cell cycle with implication in #cancer." 🧬 Hosted by the Si Lab. #SciSky #ResearchSky

Excited to share our latest publication, out in @science.org! We define a key role for the CST complex in double-strand break repair pathway choice. This study was conducted in close collaboration with the Sung lab at UT Health San Antonio. Congrats to @michelleswift.bsky.social and all authors!

CTC1-STN1-TEN1 controls DNA break repair pathway choice via DNA end resection blockade

Antagonistic activities of the 53BP1 axis and the tumor suppressor BRCA1-BARD1 determine whether DNA double-strand breaks (DSBs) are repaired by end joining or homologous recombination. We show that t...

science.org