Any EEG expert in phase-amplitude coupling interested in looking into high-density psychedelic datasets? Please DM

Volunteers wanted in London for a DMT study to reduce alcohol consumption, by colleagues at UCL. More info in the link here www.psychedelicunit.com/unity-alcohol

NEW from me: Political hostility, high visa fees and (in the case of the UK) stagnant incomes are making the UK and US less attractive destinations for top international talent. That steep decline in the appeal of moving to the US after 2016 is 👀

NEW TEN-PART AUDIO SERIES about #PSYCHEDELICS Out now on BBC Sounds - and other podcast spaces. Co-written & presented by the beautifully curious @timhayward.bsky.social Production, sound design and mix by me. It's been a fascinating and challenging process to get here... I do hope you'll listen.

BBC Radio 4 - Understand, The Trip

Tim Hayward looks at the science, culture, history - and future - of psychedelics.

bbc.co.uk

With immense pleasure, here is our #TICS opinion paper on "mind blanking"! @cp-trendscognsci.bsky.social **Where is my mind?** A neurocognitive investigation of mind blanking www.sciencedirect.com/science/arti... With Jenny Windt, @antoinelutz.bsky.social and @ademertzi.bsky.social

Our new paper - the first peer-reviewed brain and phenomenological examination of 5-MeO-DMT is out in Neuro of Consciousness. TLDR: We tested whether ‘the mount Everest’ of psychedelics could induce a complete state of consciousness deconstruction while preserving awareness. 1/n #neuroskyence

Age-related differences in 1/f aperiodic EEG/MEG signals can be driven by cardiac rather than brain activity 👇 #interoception 🧠🫀 #neuroskyence elifesciences.org/reviewed-pre...

Check this out by Jeremy Skipper at @thelablab.bsky.social iai.tv/articles/lan...

Language creates an altered state of consciousness | Jeremy I Skipper

iai.tv

Maybe a good time to remember that mice have tiny hyperconnected brains. An estimated 97% of all possible connections between brain areas exist in mice, vs ~62% in macaques and marmosets. No wonder everything is everywhere in mice, they have all-to-all connectivity! doi.org/10.1093/cerc...

The meso-connectomes of mouse, marmoset, and macaque: network organization and the emergence of higher cognition

Abstract. The recent publications of the inter-areal connectomes for mouse, marmoset, and macaque cortex have allowed deeper comparisons across rodent vs.

doi.org

The Transmitter @thetransmitter.bsky.social · 2y ago

The majority of cells in the cerebral cortex are unspecialized, according to an unpublished analysis—and scientists need to take care in naming neurons, the researchers warn. By Holly Barker www.thetransmitter.org/neural-codin...

2/ Our comment is a response to both the charge from 'IIT-concerned et al' that IIT is pseudoscientific (we disagree) www.nature.com/articles/s41... and to the response by Tononi et al www.nature.com/articles/s41...

Congrats to Lisa Luan for a successful PhD defence leading our extended DMT studies at @imperialcollegeldn.bsky.social . Very proud to call her my first completed PhD student and in awe of how she managed to meticulously carry out some of the most extreme studies one could think of

www.nature.com/articles/s41... Loneliness and social isolation literally kills 👇🏼

Plasma proteomic signatures of social isolation and loneliness associated with morbidity and mortality - Nature Human Behaviour

Shen et al. characterize protein signatures in the blood associated with social isolation and loneliness, demonstrating how these link social isolation and loneliness to an increased risk of disease a...

nature.com

Benny Shanon, one of the pioneers of modern psychedelic research, has recently passed away. If you haven't done so, check out his book Antipodes of the Mind, one of the most influential and beautiful books I have read. May his contributions carry forward in our work and explorations of consciousness

Psychedelic-mediated Reversal of General Anesthesia and Restoration of Brain Dynamics in Rat www.biorxiv.org/content/10.1...

If you have experience with psychedelics or meditation please consider participating and sharing

The LAB Lab 🏳️‍🌈🏳️‍⚧️@thelablab.bsky.social · 2y ago

⭐ Do you have experience with #psychedelics 🍄 or #meditation 🪷? ⭐ 🆘 Please help us understand how these practices shape the experience of emotions in our bodies. 🔬 Contribute to science by taking part in a quick, 20-min anonymous online experiment. 🖱️ Click here to participate: bit.ly/3DYMEkb

'The narrative and embodied dimensions of psychedelic integration' anthrosource.onlinelibrary.wiley.com/doi/10.1111/...

Anthropology of Consciousness | AAA Journal | Wiley Online Library

Within recent years, an increasing number of people and researchers in the Global North have become interested in psychedelic substances and their therapeutic application. While much of the current m...

anthrosource.onlinelibrary.wiley.com

Really excited about this paper out today in @natureneuro.bsky.social If you are interested in how to characterise the role of the DMN in human cognition you really should check it out. a 🧵

Boris Bernhardt@borismontreal.bsky.social · 2y ago

Out in @natureneuro.bsky.social today 🥂 Cytoarchitecture, wiring and signal flow of the human default mode network Combining 3D histology, 7T MRI, and connectomics to explore DMN structure-function associations Led by Casey Paquola, @themindwanders.bsky.social & a terrific team of colleagues 🙏

Out in @natureneuro.bsky.social today 🥂 Cytoarchitecture, wiring and signal flow of the human default mode network Combining 3D histology, 7T MRI, and connectomics to explore DMN structure-function associations Led by Casey Paquola, @themindwanders.bsky.social & a terrific team of colleagues 🙏

The architecture of the human default mode network explored through cytoarchitecture, wiring and signal flow - Nature Neuroscience

The default mode network (DMN) is implicated in cognition and behavior. Here, the authors show that the DMN is cytoarchitecturally heterogeneous, it contains regions receptive to input from the sensory cortex and a core relatively insulated from environmental input, and it uniquely balances its output across sensory hierarchies.

nature.com

Hi everyone, we have published a new paper showing that #psilocybin increases emotional #empathy in patients living with depression for at least two weeks after a single administration. If you are interested in #psychedelics and #social cognition, take a look here: www.nature.com/articles/s41...

Psilocybin increases emotional empathy in patients with major depression - Molecular Psychiatry

Molecular Psychiatry - Psilocybin increases emotional empathy in patients with major depression

nature.com

Does the culture you grow up in shape the way you see the world? In a new Psych Review paper, @chazfirestone.bsky.social & I tackle this centuries-old question using the Müller-Lyer illusion as a case study. Come think through one of history's mysteries with us🧵(1/13):

Is our brain infinitely flexible or constrained? Oby & colleagues cleverly uses BCIs to test what cortical activity can/can't be generated quickly. Highly recommend! www.nature.com/articles/s41... And you can get a tl;dr + my takes on why this is exciting here: www.nature.com/articles/s41...

Dynamical constraints on neural population activity - Nature Neuroscience

Oby, Degenhart, Grigsby and colleagues used a brain–computer interface to challenge monkeys to override their natural time courses of neural activity. They found the time courses to be highly robust, ...

nature.com

Very proud to have contributed to this work with @matthewsacchet.bsky.social and his team exploring the neurophenomenology of advanced Jhana meditation. Notice the strong similarities with psychedelic states, especially in EEG findings. Stay tuned for more www.sciencedirect.com/science/arti...

Multimodal neurophenomenology of advanced concentration absorption meditation: An intensively sampled case study of Jhana

Using a combination of fMRI, EEG, and phenomenology ratings, we examined the neurophenomenology of advanced concentrative absorption meditation, namel…

sciencedirect.com

Why inflammatory reductionism is a threat to psychiatry (and the rest of medicine) academic.oup.com/brain/advanc... Fascinating from Tom Pollak (not on BlueSky?) - via @annaciaunica.bsky.social

Why inflammatory reductionism is a threat to psychiatry (and the rest of medicine)

A new world-view is emerging, one which attempts to explain all manner of ills as the result of inflammation or immune dysfunction. While motivated by some

academic.oup.com

Our review on the theoretical status of oscillations and field potentials is out! What are their effects, and what can electrophysiology signals reveal about how the brain works? w/ @dlevenstein.bsky.social @prokraustinator.bsky.social Bradley Voytek @rdgao.bsky.social www.cell.com/trends/cogni...

Processes and measurements: a framework for understanding neural oscillations in field potentials

Various neuroscientific theories maintain that brain oscillations are important for neuronal computation, but opposing views claim that these macroscale dynamics are ‘exhaust fumes’ of more relevant processes. Here, we approach the question of whether oscillations are functional or epiphenomenal by distinguishing between measurements and processes, and by reviewing whether causal or inferentially useful links exist between field potentials, electric fields, and neurobiological events. We introduce a vocabulary for the role of brain signals and their underlying processes, demarcating oscillations as a distinct entity where both processes and measurements can exhibit periodicity. Leveraging this distinction, we suggest that electric fields, oscillating or not, are causally and computationally relevant, and that field potential signals can carry information even without causality.

cell.com

Our work with DMT featured in this extensive piece in Vox @vox.com www.vox.com/the-highligh...

The world’s most mysterious psychedelic is already inside your brain

DMT, “the nuclear bomb of the psychedelic family,” explained.

vox.com

Eduardo furthers this key discussion of how we validate experience/context-based therapies such as psychedelic therapy

Eduardo Schenberg, PhD@eeschenberg.bsky.social · 2y ago

⚠️ My new preprint examines the opposite conclusions of the 🇺🇸FDA👎 and 🇳🇱Dutch Commission👍 about #MDMA therapy for PTSD. I suggest that FDA more closely followed the hierarchy of EBM, while the Dutch approached what a pluralistic EBM+ assesment would look like. #psychiatry #neuroskyence #PhilSci

🎉 Our paper "Criterion placement threatens the construct validity of neural measures of consciousness" is now out in eLife! 🎉 TL;DR: Both simulations and empirical data show that you should not post-hoc sort neural data based on subjective measures of consciousness. elifesciences.org/reviewed-pre...

My presentation at the Models of Consciousness Conference showing preliminary findings assessing the potential of the powerful psychedelic 5-MeO-DMT to induce an absolutely deconstructed state of consciousness while preserving consciousness www.youtube.com/watch?v=iY7h...

Christopher Timmermann - Preliminary findings of the utility of employing 5-MeO-DMT to study MPEs

YouTube video by Models of Consciousness Conferences

youtube.com

I’m super excited to announce I'm part of an amazing team (<3 @williambrady.bsky.social @killianmcloughlin.bsky.social @mjcrockett.bsky.social) that just published a paper in @science.org on the role of outrage in spread of misinformation Link here: science.org/doi/10.1126/... Summary in🧵🔽 1/