Centre d'Infection et d'Immunité de Lille

@ciilofficiel.bsky.social

The Center for Infection and Immunity of Lille develops research projects on the molecular and cellular mechanisms of infectious and chronic inflammatory diseases to develop and improve diagnostics, vaccines, and therapies. www.ciil.fr

📢 New pub in the International Journal of Tryptophan Research 1/4 A study led by Sabrina Marion (Univ Lille-Associate Professor) reveals that chronic Toxoplasma gondii infection induces long-term activation of the kynurenine pathway in the brain, leading to the production of neurotoxic metabolites.

Sage Journals: Discover world-class research

Subscription and open access journals from Sage, the world's leading independent academic publisher.

doi.org

Very happy to have participated in the “Health Effects of Vaccines: From Genomics to Policy” conference at Wellcome Connecting Science. Inspiring discussions on vaccines, host responses, genomics & public health. Congrats to Carine and Valentin for presenting their work!@ciilofficiel.bsky.social

Bild

📢 New publication in Nature Com by @natureportfolio.nature.com A new study led by A Baulard, N Willand and B Deprez, in collab with M Pieren and M Remuinan, report the mode of action of AlpE a novel combination therapy pairing alpibectir with ethionamide to enhance tuberculosis treatment.

Alpibectir–Ethionamide combination (AlpE) for the treatment of tuberculosis - Nature Communications

In this work, authors show that alpibectir boosts ethionamide efficacy against Mycobacterium tuberculosis by enhancing its bioactivation and also shows intrinsic activity. The ethionamide-alpibectir c...

nature.com

#CNRSLeJournal 📜 | Quand les parasites prennent le contrôle… Découvrez l’incroyable stratégie de Toxoplasma gondii, un parasite capable de manipuler le cerveau… jusqu’à modifier les comportements de ses hôtes. Cet article s’appuie notamment sur les travaux de Mathieu Gissot @gissotlab.bsky.social

Ces parasites qui nous manipulent

L’extraordinaire odyssée du toxoplasme, le parasite qui manipule ses hôtes pour les transformer en pâtée pour chat.

lejournal.cnrs.fr