NEW: Researchers at the MRC Molecular Haematology Unit, led by @ckbrierley.bsky.social & @adammead.bsky.social, have uncovered a potential new therapeutic target in BP-MPN - a particularly aggressive type of leukaemia. 🧪🧬 Read more: @oxfordbrc.bsky.social | @rdm.ox.ac.uk | @medsci.ox.ac.uk

New research reveals druggable target arising from chromosomal rearrangement in aggressive leukaemia

Researchers at the University of Oxford have uncovered a potential new therapeutic target in a particularly aggressive and hard-to-treat form of leukaemia.

imm.ox.ac.uk

🚨🚨Paper out! 🚨🚨 Delighted to share our work, now published in ‪@natgenet.nature.com‬ 🧬! shorturl.at/94s5S We identified a targetable, chromothripsis-associated genetic event in blast phase (BP) MPN, a particularly poor prognostic subtype of acute leukaemia. 1/n Illustration: Hratch Arbach 🧵👇

The Splash @ASH! Stepping out of my comfort zone to flex a fledgling journalistic muscle. Many of the #ASH24 community have been generous in giving time for interviews and discussion. Now looking fwd to meeting folks in person - and the fab editorial team #ASHNewsDaily! @ash-hematology.bsky.social

Blue skies (perfect for a first post over here 🦋)and beautiful views over Greenland on a plane brimming with haematologists. A peaceful moment ahead of the tumult! #ASH24