Amyloid Accelerator Polyphosphate Implicated as the Mystery Density in α-Synuclein Fibrils https://www.biorxiv.org/content/10.1101/2024.05.01.592011v1

Amyloid Accelerator Polyphosphate Implicated as the Mystery Density in α-Synuclein Fibrils https://www.biorxiv.org/content/10.1101/2024.05.01.592011v1

Aberrant aggregation of -Synuclein is the pathological hallmark of a set of neurodegenerative diseas

biorxiv.org

Open Access UCL Research: Human plasma inositol hexakisphosphate (InsP 6 ) phosphatase identified as the Multiple Inositol Polyphosphate Phosphatase 1 (MINPP1) discovery.ucl.ac.uk/id/eprint/10...

Polyphosphate: The “Dark Matter” of Bacterial Chromatin Structure onlinelibrary.wiley.com/doi/10.1111/... #jcampubs

Polyphosphate: The “Dark Matter” of Bacterial Chromatin Structure

Polyphosphate condensates and their contributions to nucleoid structure. Polyphosphate condensates form in the ribosome-depleted nucleoid region of bacterial cells, particularly under stress (in this...

onlinelibrary.wiley.com

Proud to share our latest work with @jessenlab.bsky.social ! We optimized a method to purify polyphosphate in human cells. The paper reviews critical steps in protocols, shares physiological insights, and yes – we’ve got NMR snapshots of mammalian polyP! Read more: doi.org/10.1016/j.ym... #polyP

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