We are hiring on the IBM Core AI team. Feel free to DM me. 🙂 Job posting form - forms.gle/zZ2FHDg5sPVq... Our group builds the technology that makes agentic AI reliable, observable, and governable at enterprise scale, with open research and tooling for evaluating agents and improving them.

After nearly a decade in academia, I am thrilled to share my next chapter: I am joining IBM as an AI Architect in the new Core AI group. We are building an AgentOps platform to observe, evaluate, and optimize enterprise AI agents and we are hiring. DM me if interested.

Very happy for this to finally be published! We developed new machine learning methods for scalable mapping of synaptic connectivity using holographic optogenetics and compressed sensing. www.nature.com/articles/s41...

Nature Neuroscience@natneuro.nature.com · 11mo ago

A pair of papers on using holographic optogenetics and compressed sensing for connectomics: Rapid learning of neural circuitry from holographic ensemble stimulation enabled by model-based compressed sensing www.nature.com/articles/s41...

We present our preprint on ViV1T, a transformer for dynamic mouse V1 response prediction. We reveal novel response properties and confirm them in vivo. With @wulfdewolf.bsky.social, Danai Katsanevaki, @arnoonken.bsky.social, @rochefortlab.bsky.social. Paper and code at the end of the thread! 🧵1/7

Two flagship papers from the International Brain Laboratory, now out in ‪@Nature.com‬: 🧠 Brain-wide map of neural activity during complex behaviour: doi.org/10.1038/s41586-025-09235-0 🧠 Brain-wide representations of prior information in mouse decision-making: doi.org/10.1038/s41586-025-09226-1 +

Excited to co-organize our NeurIPS 2025 workshop on Foundation Models for the Brain and Body! We welcome work across ML, neuroscience, and biosignals — from new approaches to large-scale models. Submit your paper or demo! 🧠 🧪 🦾

Mehdi Azabou@mehdiazabou.bsky.social · last yr.

Excited to announce the Foundation Models for the Brain and Body workshop at #NeurIPS2025! 🧠📈 🧪 We invite short papers or interactive demos on AI for neural, physiological or behavioral data. Submit by Aug 22 👉 brainbodyfm-workshop.github.io

Excited to announce the Foundation Models for the Brain and Body workshop at #NeurIPS2025! 🧠📈 🧪 We invite short papers or interactive demos on AI for neural, physiological or behavioral data. Submit by Aug 22 👉 brainbodyfm-workshop.github.io

Neural Encoding and Decoding at Scale (NEDS) is now accepted to @icmlconf.bsky.social as a spotlight (top 2.6%)! 🧠 🧪

Cole Hurwitz@colehurwitz.bsky.social · last yr.

Another step toward a foundation model of the mouse brain: "Neural Encoding and Decoding at Scale (NEDS)" Trained on neural and behavioral data from 70+ mice, NEDS achieves state-of-the-art prediction of behavior (decoding) and neural responses (encoding) on held-out animals. 🐀

Super cool. 😀 Exciting to see the practical use cases of electrical stimulation for treating neurological disorders

We’re hiring postdocs to join my lab at UNC. If you’re interested in adolescence, brain, and social development, DM me. Our work incorporates fMRI, social media, and longitudinal methods. We study risks and opportunities in adolescence. If you’re at #SRCD2025 and want to meet, please reach out!

I asked "on the other platform" what were the most important improvements to the original 2017 transformer. That was quite popular and here is a synthesis of the responses:

Whoever is at the @iclr-conf.bsky.social workshops, feel free to reach out to meet! Looking for fun neuro conversations since there aren’t any neuro workshops 😢

Scaling models across multiple animals was a major step toward building neuro-foundation models; the next frontier is enabling multi-task decoding to expand the scope of training data we can leverage. Excited to share our #ICLR2025 Spotlight paper introducing POYO+ 🧠 poyo-plus.github.io 🧵

Thrilled to share our state-of-the-art method for in vivo cell-type classification and brain region localization, NEMO, which is now now a spotlight at @iclr-conf.bsky.social ! We use NEMO to characterize the electrophysiological diversity of cell-types across the entire mouse brain. 🐭 🧪 🧠

Agreed! But here's a note of caution: in the brain, different behavioral contexts can engage completely different neurons! Julie Lee in our lab published this in 2022 (and I'm still digesting the implications). "Task specificity in mouse parietal cortex" www.cell.com/neuron/fullt...

Thanks so much for the shout-out, and congrats on your exciting work!! 🎉 🙂 Also, a good reminder to share that our work is now out in Cell Reports 🙏🎊 ⬇️ www.cell.com/cell-reports...

Modeling conditional distributions of neural and behavioral data with masked variational autoencoders

Schulz et al. demonstrate how neural encoding and decoding can be cast as computing conditional distributions and how to modify variational autoencoders (VAEs) to calculate such distributions. The pro...

cell.com

Cole Hurwitz@colehurwitz.bsky.social · last yr.

Current neurofoundation modeling approaches focus on either predicting neuronal responses (Wang et al. 2025) or behavior (POYO, POYO+, NDT2). Inspired by Schulz et al. 2025, we unify these two tasks using a multimodal masked modeling approach we call "Neural Encoding and Decoding at Scale (NEDS)"

Very cool work here from @colehurwitz.bsky.social and others, and an important step towards a proper foundation model for neuroscience. Wonderful to see the scaling effects of moving from single session to multisession! (Also, a great use of the IBL data, IMO). #NeuroAI 🧠📈 🧪

Cole Hurwitz@colehurwitz.bsky.social · last yr.

Another step toward a foundation model of the mouse brain: "Neural Encoding and Decoding at Scale (NEDS)" Trained on neural and behavioral data from 70+ mice, NEDS achieves state-of-the-art prediction of behavior (decoding) and neural responses (encoding) on held-out animals. 🐀

Another step toward a foundation model of the mouse brain: "Neural Encoding and Decoding at Scale (NEDS)" Trained on neural and behavioral data from 70+ mice, NEDS achieves state-of-the-art prediction of behavior (decoding) and neural responses (encoding) on held-out animals. 🐀

Interested in foundation models for #neuroscience? Want to contribute to the development of the next-generation of multi-modal models? Come join us at IVADO in Montreal! We're hiring a full-time machine learning specialist for this work. Please share widely! #NeuroAI 🧠📈 🧪

IVADO@ivado.bsky.social · last yr.

🔍 [Job Offer] #MachineLearning Specialist. Join the IVADO Research Regroupement - AI and Neuroscience (R1) to develop foundational models in the field of neuroscience. More info: ivado.ca/2025/04/08/s... #JobOffer #AI #Neuroscience #Research #MachineLearning

Amazing work led by @ninelk.bsky.social. This work introduces BAND, a new approach for modeling the dynamics underlying neural and behavioral data. Using this approach, @ninelk.bsky.social was able to capture feedback-driven motor corrections which were previously missed!

Nina Kudryashova@ninelk.bsky.social · last yr.

Excited to share our new pre-print on bioRxiv, in which we reveal that feedback-driven motor corrections are encoded in small, previously missed neural signals.

I'll be giving a talk at the foundation model workshop #Cosyne2025 tomorrow: neurofm-workshop.github.io In response to @thetransmitter.bsky.social article by @tyrellturing.bsky.social & Eva Dyer I'll be talking about: How do "foundation"/AI models help us (experimenters) study the brain?

COSYNE 2025 Workshop - Building a foundation model for the brain

Join us to explore neuro-foundation models. March 31-April 1, 2025 in Mont Tremblant, Canada.

neurofm-workshop.github.io

Eva Dyer and I wrote an opinion piece for @thetransmitter.bsky.social on why neuroscience needs to embrace complexity and accept the "bitter lesson" by using a data-driven regime at scale. With commentary from several wonderful researchers! 🧠📈 #NeuroAI 🧪

The Transmitter @thetransmitter.bsky.social · last yr.

How can we make progress in developing a general model of neural computation rather than a series of disjointed models tied to specific experimental circumstances, ask Eva Dyer and @tyrellturing.bsky.social in the latest entry in our NeuroAI series. www.thetransmitter.org/neuroai/acce...

Cosyne is this week! Looking forward to catching up with whoever is there. :-) #Cosyne2025 If you are sticking around for workshops, come checkout our 2-day workshop on building foundation models for the brain: neurofm-workshop.github.io 🧠 🧪

COSYNE 2025 Workshop - Building a foundation model for the brain

Join us to explore neuro-foundation models. March 31-April 1, 2025 in Mont Tremblant, Canada.

neurofm-workshop.github.io

The International Brain Laboratory reproducibility platform paper is now published at eLife. An amazing effort by many different labs and individuals to understand and improve the reproducibility of electrophysiological measurements in mice. 🧠

Join us at #COSYNE2025 to explore recent advancements in large-scale training and analysis of brain data! 🧠🟦 We also made a starter pack with (most of) our speakers: go.bsky.app/Ss6RaEF

Neuro-foundation models Workshop - COSYNE 2025

Join the conversation

go.bsky.app

Avery HW Ryoo@averyryoo.bsky.social · last yr.

How can large-scale models + datasets revolutionize neuroscience 🧠🤖🌐? We are excited to announce our workshop: “Building a foundation model for the brain: datasets, theory, and models” at @cosynemeeting.bsky.social #COSYNE2025. Join us in Mont-Tremblant, Canada from March 31 – April 1!

Super excited to be co-organizing this. 😄 We have an amazing list of speakers and some fun panel discussions planned. Come join us!

Avery HW Ryoo@averyryoo.bsky.social · last yr.

How can large-scale models + datasets revolutionize neuroscience 🧠🤖🌐? We are excited to announce our workshop: “Building a foundation model for the brain: datasets, theory, and models” at @cosynemeeting.bsky.social #COSYNE2025. Join us in Mont-Tremblant, Canada from March 31 – April 1!

"I think there's real risk of a generation or more of data being lost." - Dr. Michael Greicius, neurology professor at Stanford University, on the damage Trump's cuts to NIH research will do to progress on a treatment for Alzheimer's disease, adding as much as 20 years to the timeline.

Petition to Reverse the NIH Indirect Cost Cap. Sign and Circulate. Mobilize. Organize. chng.it/LS57Nk7r6k

This campaign needs you now

Petition to Reverse the NIH Indirect Cost Cap (NOT-OD-25-068)

chng.it

The overlapping activity in the animals’ nucleus accumbens may underpin pair bonding, a new preprint suggests. www.thetransmitter.org/social-behav... By @shaena.bsky.social 📹 Courtesy of Paul Muhlrad @wormpicker.bsky.social #neuroskyence

Curious how place cells adapt to uncertainty in reward location? We found that predictable changes boost “reward place cells” & warp hippocampal maps. Check out our new preprint: with Feng Xuan, Jack Mellor, Peter Dayan and Dan Dombeck: www.biorxiv.org/content/10.1...

Navigating uncertainty: reward location variability induces reorganization of hippocampal spatial representations

Navigating uncertainty is crucial for survival, with the location and availability of reward varying in different and unsignalled ways. Hippocampal place cell populations over-represent salient locati...

biorxiv.org