Do #tintinnids dream of electric sheep? 🤯 Here is a single cell capable of building a lorica and living inside it for protection... it also swims, feeds, hunts Can even detect and habituate to mechanical cues! #celllearning #protistsonsky #cilia Read more in our preprint doi.org/10.64898/202...

Meet Euplotes gigatrox, a super-giant cannibal captured with a scanning electron microscope for our #PictureOfTheWeek. Image credit: Ben Larson and Samuel Lord

[1/n] Our preprint-in-progress on RNA regionalization in Stentor is no longer in progress! Now @pnas.org 🥳 Turns out a single cell isn't a homogenous soup… it has molecular geography, including things like regionalized transcription factors. Think bicoid, but in a ciliate.

Genome-wide analysis of mRNA regionalization in a giant single cell | PNAS

The molecular mechanisms that produce cell structure are poorly understood. The giant ciliate Stentor coeruleus is a unicellular model organism who...

pnas.org

I'll be sharing my work on how cells know when to make missing structures at #cellbio2025 today! Come check out my poster (B406) and my talk in the Evolutionary Cell Bio mini symposium session which starts at 4pm.

Come check out my poster & talk!! #CellBio2025 #ASCB

Wallace Marshall@wallaceucsf.bsky.social · 8mo ago

The cell is a crowded place where organelles are packed together . In poster B365 at CellBio2025 Monday Dec 8 in the Quantitative Modeling session room 122, Mary Mirvis uses soft x-ray tomography to explore how packing interactions affect organelle shape and interaction.

The giant ciliate Stentor has a macronucleus that undergoes a dramatic shape change during cellular regeneration. In poster 038 at CellBio2025 Monday Dec 8, I present work by Isabella Ibalio showing that histone modifications correlate with these dramatic nuclear shape changes.

Stentor is a single cell that can regenerate missing pieces, but how does it know when something is missing? In poster 406 at CellBio2025 Monday Dec 8, Connie Yan shows that conserved cell cycle machinery plays a key role in triggering cellular regeneration.

Stentor is a single cell with a complex cortical pattern showing anterior/posterior polarization In poster 410 at CellBio2025 Monday Dec 8, Yina Hudnall shows a role for posterior-enriched mRNA that encoding DNA binding proteins.

Cells can form patterns within themselves just like embryos do. How? Connie Yan's new preprint shows how the anterior-posterior cytoskeleton pattern in Stentor is dictated by regionalized scaffolding proteins www.biorxiv.org/content/10.1...