Thanks www.nature.com/articles/s41... @marcopll.bsky.social @conormccann-ens.bsky.social @vivianlilab.bsky.social @bonfantilab.bsky.social @greatormondst.bsky.social @uclpophealthsci.bsky.social @uclnews.bsky.social @crick.ac.uk @ucl.ac.uk @uclchildhealth.bsky.social @goshcharity.bsky.social

Functional integration of an autologous engineered esophagus in a large-animal model - Nature Biotechnology

A tissue-engineered esophageal segment is functional in minipigs.

nature.com

📢REMINDER: The deadline to apply for LBBB2026 is Monday (2nd February) 📍The meeting takes place in Fusagasuga (Colombia) 31st October - 4th November 📬Apply Now to be part of a small meeting with big ideas @dgnm.bsky.social

Thinking of studying Cell, Gene and Novel Therapies? Join our online information session where you’ll meet our Programme Directors and find out what it’s like to study at a world-leading institution. 🌍 📅 Cell, Gene and Novel Therapies MSc – 12 February, 12:00-13:00 🔗 Sign up: bit.ly/4bwZXah

Graduate Open Events: Cell, Gene and Novel Therapies

Explore our Cell, Gene and Novel Therapies MSc. Join our virtual open event to meet our Programme Directors and plan your next career step.

ucl.ac.uk

Delighted to share our paper on Hirschsprung disease outcomes in England in Frontline Gastroenterology. This work brought together multiple collaborators to explore the experiences of children with Hirschsprung disease. Thanks to all involved and a great start to 2026. fg.bmj.com/content/earl...

Childhood outcomes in children with Hirschsprung disease: a population-based data linkage study in England

Objective Hirschsprung disease (HSCR) is a rare congenital intestinal condition that, despite corrective surgery, can lead to recurrent hospitalisations and reduced quality of life throughout childhoo...

fg.bmj.com

Hot on the heels of our recent basic science preprint. Check out our preprint of a data driven study looking at Hirschsprung Disease Outcomes of children in England using ECHILD (medrxiv.org/cgi/content/...).

Childhood outcomes in children with Hirschsprung disease: a population-based data linkage study in England

Objective Hirschsprung disease (HSCR) is a rare congenital intestinal condition that, despite lifesaving surgery, can result in increased hospitalisations and a lower quality of life throughout childh...

medrxiv.org

Check out our lab’s new preprint (www.biorxiv.org/content/10.1...) on the consequences of ENS progenitor transplantation to mouse Hirschsprung disease explants. Delighted to continue a fruitful collaboration with @tsakiridis.bsky.social to develop a #celltherapy for #Hirschsprungs

Functional and molecular rescue of aganglionic colon by human enteric nervous system progenitor transplantation in Hirschsprung disease

Hirschsprung disease (HSCR) is a devastating congenital disorder characterised by absence of the enteric nervous system (ENS) in the distal gut. Cell therapy, using human pluripotent stem cell-derived...

biorxiv.org

For the fourth year running, our INSPIRE Programme (hdbi.org/inspire) is welcoming A-level students to @uclchildhealth.bsky.social this week. This has been possible thanks to Wellcome Trust and Human Developmental Initiative funding, and all our volunteers. #workexperience #childheath #research

New preprint from our group on bioRxiv, a little step towards a better understanding of how coordinated contractions develop in the human intestine. Please check it out and let us know your thoughts.

bioRxivpreprint@biorxivpreprint.bsky.social · last yr.

Purinergic signalling and calcium dynamics: potential drivers in the onset of coordinated intestinal motility in human fetal development https://www.biorxiv.org/content/10.1101/2025.04.17.649306v1

Second (BBSRC Yorkshire Bioscience DTP-funded) PhD project available in our lab (jointly with @christoseland.bsky.social) examining how biomechanical cues crosstalk with signals to influence cell fate decisions during hESC differentiation. More details here: thenode.biologists.com/jobs/funded-...