How does an embryo generate the right cells in the right place? Delighted to share our latest findings on how neural crest cells acquire vagal or trunk identities Spoiler alert: The timing & combination of CDXs preconfigures cell identity & distinct HOX states www.biorxiv.org/content/10.6...

Temporally distinct CDX programmes preconfigure vagal and trunk neural crest

Neural crest cells (NCCs) are progenitor cells vital in establishing the head, heart, gut and peripheral nervous system of vertebrate embryos. Disruptions to NCC development underlie neurocristopathie...

biorxiv.org

For the neural crest nerds: we love looking into transcriptional programs in single NCC cells. However, selective ribosomal modifications refine gene expression programs at a different scale. Here is our story about modified ribosomes in neural crest fate selection: www.nature.com/articles/s41...

Ribosomal modifications are associated with mesenchymal fate selection in the neural crest lineage - Nature Communications

Neural crest cells differentiate into skeletogenic mesenchyme and neuro-glial lineages, thereby contributing to craniofacial formation. Here, single-cell analysis of cranial neural crest shows that sp...

nature.com

🔬 Bidirectional communication between neurons in the mesentery and ileal myenteric neurons www.biorxiv.org/content/10.6...

Pleased to share our latest! We show that the chick limb can be directed to recapitulate key stages in mammalian evolution, providing a unifying model for digit patterning across amniotes. Preprint: www.biorxiv.org/content/10.6... Video summary: www.youtube.com/watch?v=fvL_...

Transforming avian to mammalian modes of digit patterning

How a conserved embryonic organiser-the Sonic hedgehog (Shh)-expressing Zone of Polarising Activity (ZPA)-generates diverse limb architectures in amniotes remains a central problem in evolutionary and...

biorxiv.org

Looking forward to an exciting programme this Monday on Developmental Origins of Paediatric Cancers, sponsored by CCLG at the Crick. @tsakiridis.bsky.social www.cclg.org.uk/information-...

Developmental origins of paediatric cancer symposium

A one-day event showcasing the latest cutting-edge research on the modelling, biology and treatment of paediatric cancers in the context of their developmental origins.

cclg.org.uk

The registration deadline for our @cclguk.bsky.social symposium on the developmental origins of paediatric cancers is closing this Friday 22nd May. A wide range of topics and a stellar speaker line-up so make sure you register! for more details check: www.cclg.org.uk/information-...

Developmental origins of paediatric cancer symposium

A one-day event showcasing the latest cutting-edge research on the modelling, biology and treatment of paediatric cancers in the context of their developmental origins.

cclg.org.uk

Anestis Tsakiridis@tsakiridis.bsky.social · 3mo ago

The program for our @cclguk.bsky.social symposium, co-sponsored by @dmmjournal.bsky.social , @neuroblastomauk.bsky.social and @parse.bsky.social on the developmental origins of paediatric cancer is now finalised (8th June, @crick.ac.uk): www.cclg.org.uk/information-...

PL retweet. Developmental Biology Course (Quintay). More information: biodesarrollo.unab.cl

Did you know that Development publishes Research Reports? These short articles emphasise an important finding, laying the groundwork for future research. Browse a selection of our latest, free-to-read Research Report highlights in our subject collection journals.biologists.com/dev/collecti...

The program for our @cclguk.bsky.social symposium, co-sponsored by @dmmjournal.bsky.social , @neuroblastomauk.bsky.social and @parse.bsky.social on the developmental origins of paediatric cancer is now finalised (8th June, @crick.ac.uk): www.cclg.org.uk/information-...

Developmental origins of paediatric cancer symposium

A one-day event showcasing the latest cutting-edge research on the modelling, biology and treatment of paediatric cancers in the context of their developmental origins.

cclg.org.uk

Summer is coming, but how will you maximize your picnic space when everyone else is doing the same? In our new preprint, we show that branched cells may have an elegant solution: As cells grow and repel neighbors, they don't just cover space, but reach a hidden order called hyperuniformity! 🧪⚛️

I’m beyond happy to share that the preprint summarising my PhD research is now online on bioRxiv! 🚀 I am very grateful to my supervisors, Karen J Liu and Andrea Serio, all the coauthors and members of both teams who have made this work possible.

Karen J Liu@karenjliu.bsky.social · 3mo ago

New pre-print on human neural crest organoids for studying developmental changes in diseases such as neuroblastoma. Heroic work from @carmenmorenogon.bsky.social bridging Liu/Serio labs @andreaserio.bsky.social with protocols from @tsakiridis.bsky.social. www.biorxiv.org/content/10.6...

Congratulations to @carmenmorenogon.bsky.social, @andreaserio.bsky.social, @karenjliu.bsky.social and the rest of the team for developing a great platform for interrogating neural crest behaviour

Karen J Liu@karenjliu.bsky.social · 3mo ago

New pre-print on human neural crest organoids for studying developmental changes in diseases such as neuroblastoma. Heroic work from @carmenmorenogon.bsky.social bridging Liu/Serio labs @andreaserio.bsky.social with protocols from @tsakiridis.bsky.social. www.biorxiv.org/content/10.6...

Our latest preprint is out: we used hPSC differentiation and quantitative modelling to dissect the role of Notch signalling, a pathway that is perturbed in Hirschsprung disease, a potentially lethal enteric neuropathy, in human enteric nervous system (ENS) progenitor dynamics (1/n)

Our excursion into the world of hPSC-derived lateral plate mesoderm progenitors, the result of a great collaboration with the lab of @matt-towers.bsky.social. For more details check the thread of @sudeuyulgan.bsky.social below-Sude has been fantastic in leading and driving this work!

Sude Uyulgan@sudeuyulgan.bsky.social · 4mo ago

How do you build the posterior end of a body? 🧫🔬🧬 I am excited to share that my PhD work on the generation of hindlimb and genital progenitors from human pluripotent stem cells is now available on BioRxiv! 🔗 www.biorxiv.org/content/10.6...

Do you do a PhD on Chromatin in this cool critter? Work with @jordisolana.bsky.social @seanflynn.bsky.social, Magda Strauss and myself @lsiexeter.bsky.social on developing #singlecell #chromatin analyses to better understand pluripotency #planarians. www.exeter.ac.uk/research/ins...

Come and join us!! www.jobs.ac.uk/job/DQZ547/r...

Research Associate - Plant Phylogenomics at University of Sheffield

Apply for the Research Associate - Plant Phylogenomics role on jobs.ac.uk, the top job board for academic positions in higher education. View details and apply now.

jobs.ac.uk

One day left until the abstract submission deadline for our symposium on the developmental origins of paediatric cancers on the 8th of June! If you do not want to submit an abstract please note that there is still time to register after the 20th of March

Anestis Tsakiridis@tsakiridis.bsky.social · 5mo ago

Abstract deadline extended to 20 March for our @cclguk.bsky.social @biologists.bsky.social-DMM symposium on the developmental origins of paediatric cancers (8 June, @crick.ac.uk)-short talk slots still available. See: www.cclg.org.uk/information-... Please RT!

One week left until the abstract submission deadline for our symposium on the developmental origins of paediatric cancers on the 8th of June!

Anestis Tsakiridis@tsakiridis.bsky.social · 5mo ago

Abstract deadline extended to 20 March for our @cclguk.bsky.social @biologists.bsky.social-DMM symposium on the developmental origins of paediatric cancers (8 June, @crick.ac.uk)-short talk slots still available. See: www.cclg.org.uk/information-... Please RT!

Abstract deadline extended to 20 March for our @cclguk.bsky.social @biologists.bsky.social-DMM symposium on the developmental origins of paediatric cancers (8 June, @crick.ac.uk)-short talk slots still available. See: www.cclg.org.uk/information-... Please RT!

Developmental origins of paediatric cancer symposium

A one-day event showcasing the latest cutting-edge research on the modelling, biology and treatment of paediatric cancers in the context of their developmental origins.

cclg.org.uk

Today’s seminar, hosted jointly by DRN and the Cancer Research Seminar Track (CREST) @sheffielduni.bsky.social: Dr Duncan Sproul @sproullab.bsky.social, Institute of Genetics and Cancer, Univ. Edinburgh @edinburghuni.bsky.social Host: Anestis Tsakiridis @tsakiridis.bsky.social All welcome!

Final call for everyone interested in the links between developmental biology and childhood cancer: only 2 days remaining to register and submit abstracts for our @cclguk.bsky.social, @dmmjournal.bsky.social symposium on the developmental origins of paediatric cancers taking place this June

Anestis Tsakiridis@tsakiridis.bsky.social · 6mo ago

2 weeks to go until the registration/abstract submission deadline for our @cclguk.bsky.social @dmmjournal.bsky.social symposium on the developmental origins of paediatric cancers at the @crick.ac.uk this June. Great speaker line up and slots for short talks: www.cclg.org.uk/information-...

PDRA position still open in my lab for anyone who wants to solve some outstanding questions in limb development. We have a variety of models and approaches (everything from stem cells to chicks and catsharks). Please share!

Matt Towers@matt-towers.bsky.social · 6mo ago

A BBSRC-funded PDRA position is available in my lab investigating vertebrate limb development! Please contact me for more details. www.jobs.ac.uk/job/DQH553/r....

🎗️#InternationalChildhoodCancerDay! Every year, around 400,000 children worldwide are diagnosed with cancer. Progress is possible: through research, international collaboration and close cooperation between science and clinical care. Read more:🔗 ccri.at/internationa...

International Childhood Cancer Day: Research as the key to better survival rates - St. Anna CCRI

International Childhood Cancer Day: Research as the key to better survival rates (Vienna, February 15, 2026) Every year, around 400,000 children and adolescents worldwide are diagnosed with cancer, wi...

ccri.at

2 weeks to go until the registration/abstract submission deadline for our @cclguk.bsky.social @dmmjournal.bsky.social symposium on the developmental origins of paediatric cancers at the @crick.ac.uk this June. Great speaker line up and slots for short talks: www.cclg.org.uk/information-...

Developmental origins of paediatric cancer symposium

A one-day event showcasing the latest cutting-edge research on the modelling, biology and treatment of paediatric cancers in the context of their developmental origins.

cclg.org.uk

Last couple spots remaining for the Craniofacial GRC in sunny CA! Looks to be a full house, with a great set of up-and-coming #craniofacial biologists spanning evo/devo, genetics, multiomics all the way to stem cells, engineering and repair. @brugmannlab.bsky.social www.grc.org/craniofacial...

Appalling news for the biosciences in the UK. I have three grants under review at the moment so the last week since I heard these rumours have been a definite career low point. Shifting priorities (read political interference) are bad enough www.researchprofessionalnews.com/rr-news-uk-r...

MRC instructs grant review boards to slash funding rates - Research Professional News

Boards asked to recommend just three applications for funding, as BBSRC also suspends calls

researchprofessionalnews.com

Check out this postdoc opportunity in a great lab in Sheffield! 🐣🔬

Matt Towers@matt-towers.bsky.social · 6mo ago

A BBSRC-funded PDRA position is available in my lab investigating vertebrate limb development! Please contact me for more details. www.jobs.ac.uk/job/DQH553/r....

I am completely baffled by the total lack of any action or any evidence of speaking out from our scientific ‘leaders’. We’re in a void of information and the consequences are potentially catastrophic- especially as it looks like BBSRC are following suit.

Stefan Marciniak@profmarciniak.bsky.social · 6mo ago

Has the MRC research funding ‘pause’ been covered by any major news network? It feels like it should be a major news story

The lab turned 10 this month, what better way to celebrate than with an amazing cake from @faycooper.bsky.social! I feel lucky to have worked alongside so many talented students, postdocs, and colleagues here in Sheffield over the years.

🚨DEADLINE TOMORROW FRIDAY 16th JANUARY If you are interested in DevBio, *don't think about it twice* 👇STEPS: 1)Submit an abstract bsdb.org/meetings/ 2)Become a @bsdb.bsky.social member if you aren't already bsdb.org/about-us/#me... 3)Apply for travel grants bsdb.org/membership/#... See you there!