CRC1218
@crc1218.bsky.social
The #CRC1218 tackles the challenge of understanding how #mitochondria communicate with the rest of the #cell to regulate fundamental processes. Funded by #dfg https://sfb1218.uni-koeln.de/
🚴City Cycling 2026 – Mission accomplished! Congrats to the mitoCRC team, especially Robert Düster and Alex Kaczmarek, our top riders! As part of the University Hospital team we finished second in all of Cologne 💪 Thanks to everyone who pedaled with us towards a healthier & more sustainable future🌍
🌱 Small Changes, Big Impact! 🌱 At yesterday’s Sustainability Lunch Talk of the @unicologne.bsky.social, CRC1218 PI and Sustainability Board member @valentinapiano.bsky.social shared insights into sustainable research practices, highlighting implemented measures, opportunities, and challenges.
📢A research team led by CRC1218 PI Dr. Mauro Corrado discovered that the lipid cardiolipin helps control the immune response in the gut and influences inflammation severity. Congratulations to Dr. Mauro Corrado and the entire team on their publication!👏 www.nature.com/articles/s42...
Cardiolipin preserves Treg metabolic fitness and immune homeostasis in the gut - Nature Metabolism
This study describes that cardiolipin deficiency-induced mitochondrial dysfunction in Treg cells impairs gut–immune tolerance.
nature.com
👉Paper alert👈 The @riemerlab.bsky.social discovered that cytosolic PRDX1 acts as an extramitochondrial sink to set mitochondrial H2O2 levels and enable resilience to chronic mitochondrial oxidative stress. Congrats to all researchers involved! 👏 www.sciencedirect.com/science/arti...
Cytosolic PRDX1 acts as an extramitochondrial sink to set mitochondrial H2O2 levels and enable resilience to chronic mitochondrial oxidative stress
Hydrogen peroxide (H2O2) plays a dual role as both a signalling molecule and a mediator of oxidative stress. Although mitochondria are major producers…
sciencedirect.com
👉Join the City Cycling challenge from 10 to 30 June 2026! 🚴♀️ Let's collect kilometers and make a difference—for our health and the climate 🌱 Sign up with the mitoCRC1218 subgroup under Gesunde Uniklinik and start pedaling! Every km counts—are you in? 💪 www.stadtradeln.de/index.php?id...
🚨Be quick! Registration is filling up fast!🚨 More than half of the registration spots for the international conference "Mitochondria Volume 3" have already been taken. Register soon if you'd like to attend this fantastic opportunity! 👉Register now: mitochondria-volume3.uni-koeln.de #mitochondria
🚨 Registration is open! 🚨 Join us for "Mitochondria Vol. 3: Mitochondrial Plasticity in Metabolism and Signalling", a free-of-charge international conference organized by the CRC 1218! 🗓 When: 05–07 October 2026 📍 Where: MTI, UzK Cologne, Germany 👉 Register now: mitochondria-volume3.uni-koeln.de
The 2-day CRC1218 PI Retreat at Schloss Burgbrohl has successfully concluded last week. In a beautiful setting, the retreat brought together engaging scientific talks, lively discussions, and inspiring exchange. We sincerely thank all participants for their contributions and enthusiasm!
We’re excited to share that also this year, we’ve offset CO2 emissions for all travel grants awarded to our early career researchers in 2025! 🌱 The CRC1218 is committed to fostering scientific progress while protecting the planet🌍 #SustainableScience #ScienceForTheFuture
🌟 Exciting Kick-off for our Female Mentoring Program! 🌟 Last Friday our mentees kicked off their journey with a hands-on workshop, learning the core principles of effective mentoring and how to build an independent, impactful mentoring relationship. 💪✨ #WomenSupportingWomen #FemaleMentoring
A publication rarity these days: An author list significantly shorter than the paper title! www.nature.com/articles/s41... Congratulations to our Advanced PostDoc Grant Awardee, Qiaochu Li (@qiaochuli.bsky.social), for her discoveries published in NCB [see thread]:
Leucine inhibits degradation of outer mitochondrial membrane proteins to adapt mitochondrial respiration - Nature Cell Biology
Li et al. uncover a connection between metabolic cues and mitochondrial protein degradation, showing that specifically leucine stabilizes outer mitochondrial membrane proteins by inhibiting ubiquityla...
nature.com
Congratulation also to the @riemerlab.bsky.social who just identified FAM136A as a new substrate of the mitochondrial disulphide relay and its implementations in IMS proteostasis and cellular fitness. Check it out: www.sciencedirect.com/science/arti...
The mitochondrial disulphide relay substrate FAM136A safeguards IMS proteostasis and cellular fitness
The mitochondrial disulphide relay is the key machinery for import and oxidative protein folding in the mitochondrial intermembrane space. Among IMS p…
sciencedirect.com
👉Paper alert👈 Check out the latest read from the Schwarz lab: Fu and Kohl identify persulfidation loss and hydrogen sulfide release as consequence of full-body SOX-deficiency in mice. Congratulations to everybody involved!👏 www.jci.org/articles/vie...
JCI - Sulfite oxidase deficiency causes persulfidation loss and hydrogen sulfide release
jci.org
📣Publication alert📣 A wonderful collaborative effort of the CRC 1218: The lab of Mafalda Escobar-Henriques reveals that C-terminally extended ubiquitin (CxUb) is essential for mitophagy, proteostasis and longevity through a previously undefined CxUb-Ufd2 axis. www.sciencedirect.com/science/arti...
Ubiquitin precursor with C-terminal extension promotes proteostasis and longevity
Ubiquitin is a conserved modifier regulating the stability and function of numerous target proteins. In all eukaryotes, polyubiquitin precursors are g…
sciencedirect.com
A big thank you to Thomas Splettstößer for leading an insightful Adobe Illustrator workshop on visual communication in science for our PhDs & PostDocs! We’re excited to apply what we’ve learned! 🙌 #AdobeIllustrator #VisualCommunication #Science #WorkshopSuccess
What an exciting step in the careers of Camilla Franchino, Deniz Savcigil and Sandrina Campos Macas, who just joined our Mentoring Program! Promoting career advancement and professional development through impactful networking. We wish you a successful journey!👩🔬🚀 #CareerDevelopment #WomenEmpowerment
🚴 This. was. great! 🚴♀️ In this year‘s #CityCycling, the #mitoCRC made it into the #Top10 of the Uniclinis, which was the best team in all of Cologne! Well done! We are really impressed by all the #sustainability enthusiasts around us! Photo: Our youngest team member😍 #Stadtradeln #Köln #Klimaschutz
What an outstanding achievement by our #mitoRTG member Annamaria Regina, (@annamariaregina.bsky.social)! We are extremely proud of your #passion and engagement in #ScienceCommunication! #FameLab
@annamariaregina.bsky.social · last yr.Took part in the FameLab germany final✨ 1,000 people, great vibes! Thanks to all, and good luck to the winners Naomi & Artem at the international stage! 🌍🎤 #FameLab #ScienceCommunication
📣Lecture Announcement📣 Join us: Next Monday, the CRC 1218 and the CRC 1403, will host an interactive lecture on #ResearchDataManagement - "Folders and File Names 101: Because organising data can be hard". Don't miss it: 🗓️ 23.06. at 10 AM 📍CECAD Lecture Hall @sfb1403.bsky.social #datascience
🏆We are extremely proud of our Vice Spokesperson Prof. Aleksandra Trifunovic who just received the Max Delbrück Award 2025 of @unicologne.bsky.social. A well-deserved recognition of her outstanding scientific achievements. Congrats!🎉 ▶️ youtu.be/ayE9q9nKvyc #mitochondria #lifescience #UniKöln
Prof. Dr. Aleksandra Trifunovic // Max Delbrück-Preis 2025
YouTube video by UniversitaetzuKoeln
youtu.be
Congratulations to our mitoCRC project leader Prof. Jens Brüning on receiving the University Award 2024 in the category of Research of @unicologne.bsky.social in recognition of his exceptional scientific achievements!
Universität zu Köln@unicologne.bsky.social · last yr.🎉 Herzlichen Glückwunsch an Prof. Dr. Jens C. Brüning für den diesjährigen #Universitätspreis Forschung. 🏆 🧠 Er hat herausgefunden, wie das #Gehirn den Energiehaushalt und den Appetit reguliert, besonders bei #Übergewicht und #Diabetes. Mehr dazu ▶️ youtu.be/isnxCcTMBBA @cecad.bsky.social
Big congratulations to the three awardees of our mitoCRC Advanced PostDoc Grant! We're thrilled to support Dr. Qiaochu Li, Dr. @aleksandra-zecic.bsky.social and Dr. Andromachi in their first steps toward an independent research line. Well-deserved success! 🎉 #mitochondria #PostDoc #womeninscience
In their Review, Eleonora Zilio, Elena Rugarli and colleagues @cecad.bsky.social @crc1218.bsky.social discuss the role of mitochondrial mRNA translation in cellular communication. journals.biologists.com/jcs/article/... #JCSMitoSI #Mitochondria
🚴♂️ mitoCRC joins #Stadtradeln 2025! From June 11–July 1, we’re cycling for climate & health – and challenging @crc1678.bsky.social & CRC 1403! Join our team “CRC 1218 – mitoCRC” (under Gesunde Uniklinik) and help us pedal to victory! 🌍💪 🔗 Register: www.stadtradeln.de/koeln #BikeForClimate #mitoCRC
STADTRADELN - Radeln für ein gutes Klima
Beim Wettbewerb STADTRADELN trittst du 21 Tage in die Pedale für mehr Radförderung, Klimaschutz und Lebensqualität in deiner Kommune.
stadtradeln.de
In recognition of his key role in the #mitoCRC and his valuable skill set, we’ve awarded our talented PostDoc Robert Düster a Family Support Grant! We hope to support the reconciliation of work and family life to better promote young talents in science. #mitoResearch #Equality #FamiliesInScience
📢Registration open!📢 So proud to see our very own Elisa Motori co-hosting this exciting EMBO Workshop: “Mitochondria in the Nervous System” Co-sponsored by the CRC1218! Two invited speakers of the CRC1218! Don’t miss out! 🗓 29.09.-02.10.2025 📍Engelberg, CH 👉 meetings.embo.org/event/25-mit...
👩🔬mito-RTG at KölnerKinderUni👨🔬 The mitoRTG hosted 2 workshops at the KölnerKinderUni! Future scientists aged 8 to 12 learned in hands-on experiments how the uniqueness of individuals is encoded in the DNA🧬 A big thank you to Lara, Lilli and Eileen for making it all happen! #KKU2025 #ScienceForKids
