If I were you, I'd wish @davidamuller.bsky.social a happy birthday 🎁🎉🥳🎂

Hey look @nozomi-ando.bsky.social

bioRxiv Biochemistry@biorxiv-biochem.bsky.social · last wk.

Recovery of a minor cryo-EM particle population reveals conformational equilibria linking cofactor loading, turnover, and reactivation in methionine synthase https://www.biorxiv.org/content/10.64898/2026.07.27.741092v1

17 years ago, on a day like today, I had my thesis defense. Definitely one of my favorite presentations ever, even though I was so nervous. So many wonderful developments have happened since then.

Today I turned 45 (and my mom turned 77). I spent a quier day at home. Thinking of the craziness this last year has been. The new people I've met, the opportunities I've been given, the good fortune I've had.

Attending the B exam of one of our users. He's used SPA to do reconstructions of Si nanocages. Lots of cool stuff. I'm so proud of our users!!

Seeing Li ions at atomic resolution is hard, seeing the missing ones? Harder. Dasol's electron ptychography now images Li vacancies in a battery cathode in 3D—atom column by atom column: pubs.acs.org/doi/10.1021/... @pubs.acs.org 🧪⚛️

Atomic-Scale Imaging of Lithium Vacancies in a Battery Cathode by Multislice Electron Ptychography

Atomic-resolution imaging of battery materials is critical for identification of local defects and structural variations, which are tied to battery performance. However, since battery materials are, b...

pubs.acs.org

Today, as pretty much every day, I miss you. I miss your wisdom, your character, your sense of justice, equity, fairness. Your fight to balance the scales. I also miss your humor and humanity. I can't believe that in a world full of randomness, I got to cross paths with you. Ich liebe dich.

🧪🦠🌏🧬👇

Dan Vergano@danvergano.bsky.social · last mo.

Scientific American is being sold to LabX Media, publisher of Discover: group.springernature.com/gp/group/med... They've fired me and other union staff, ahead of June 26 vote ratification. My rates are suddenly more reasonable, if you need editing or reporting - Argonaut2026@gmail.com

Missing you and all your atoms, especially today. We should've been making you blush by singing happy birthday (very offkey) and eating that delicious fruity cake from Wegmans you liked. Happy birthday to you and Sylvia.

It's finally out! Molecular architecture of mammalian AP3:ARF1 carriers - a mechanism for lysosomal membrane protein trafficking - from a combination of #biochemistry, #cryoET and #cellbiology 📝 Paper: www.science.org/doi/10.1126/... 🧵 Thread: subsequently #teamtomo #membranetrafficking

Briggs Group@briggsgroup.bsky.social · 3mo ago

The architecture of carriers formed by AP3:ARF1 for lysosomal membrane protein transport: www.science.org/doi/10.1126/.... Work from @jggkaufman.bsky.social, in collaboration with @dgershlick.bsky.social and David Owen. @mpibiochem.bsky.social @thecimr.bsky.social

"Reached for comment by TechCrunch, Musk’s lead counsel Marc Toberoff said, 'One word: Appeal.'" [Two words, actually: "billable hours."]

Elon Musk has lost his lawsuit against Sam Altman and OpenAI | TechCrunch

Elon Musk's claim that he was mistreated by his OpenAI cofounders failed after nine California jurors decided in a unanimous verdict that his lawsuits had been filed too late.

techcrunch.com

FUUUUUUUUUCK. FUCKING FUCK. FUCKING FUCK FUCK. Massive FUCK you to the universe.

When do we start calling him a mass murderer?

Headquarters@headquartersnews.bsky.social · 3mo ago

RFK Jr. has fired every single CDC Vessel Sanitation Program inspector, who investigate cruise ship outbreaks. This comes as the deadly Hantavirus rapidly spreads on a cruise ship at sea.

Congratulations to @lapassmore.bsky.social, Joint Head of the LMB’s Structural Studies Division, who has been elected an international member of @nationalacademies.org Congratulations to #LMBalumni Andrea Brand who has also been elected. Read more: mrclmb.ac.uk/news-events/... #LMBNews

We will host a ~30-45 min webinar introducing EM-server for cryo-EM structure modeling on May 6 (Wed) 12:30pm (Eastern Time). Will introduce DAQ-Score plugin & CryoZeta. EM-Server: em.kiharalab.org Registration link: kiharalab-events.vercel.app Hope to see you there!

@sciencex.bsky.social ex.bsky.social picked up our #ptychography paper on imaging the atomic-scale roughness in transistor channels in 3D, in a single scan and without having to tilt the sample. ⚛️

Science X / Phys.org@sciencex.bsky.social · 5mo ago

High-resolution 3D electron microscopy has enabled direct visualization of atomic-scale "mouse bite" defects in semiconductor transistors, offering new insights for chip characterization and development. doi.org/hbq6sc

Atomic‑scale nickel. Zero precious metals. Serious fuel‑cell power—thanks in part to CCMR tools news.cornell.edu/stories/2026...

Nickel catalyst enables high-performance fuel cell free of precious metals | Cornell Chronicle

Cornell researchers have developed a non-precious-metal catalyst that represents a major step toward alkaline fuel cells that use inexpensive commodity metals, such as nickel and cobalt, in several en...

news.cornell.edu

Cryo-FIB lamellae enable ultra-high excitation laser intensities for cryogenic super-resolution fluorescence imaging https://www.biorxiv.org/content/10.64898/2026.04.20.719589v1

Too cool!

Edward T Eng@edwardteng.bsky.social · 4mo ago

We’re hosting an MƒA Spring 2026 MiniCourse on Unveiling Molecular Mysteries: A Journey Into Structural Biology. Over this 3-part series we’re showcasing #NMR, #X-ray crystallography & #cryoEM. Today Art Palmer, our NMR director, kicked off the series. Learn more about MfA: mathforamerica.org

Save the date: NYC-ISB26 Integrative Structural Biology symposium - Oct 8-9, 2026 Registration coming soon. Integrative structural biology is a powerful approach toward understanding biological macromolecular systems by bridging structural biology and biophysical methods. nysbc.org/nyc-isb26/

Friends on this side of the pond (US) ... any of you have a K2 Digitizer around you'd be willing to part with? Ideally manufactured from 2016 onwards. If so, feel free to let me know or if you come across @davidamuller.bsky.social somewhere in the world :). Thanks in advance!!

Yue!!!!!! ❤️❤️❤️❤️

joe dobbs@joedobbs.bsky.social · 4mo ago

People interested in the VPP aspects should also see a recent paper (from the people at Biohub) showing that tilt-series alignments can be improved with phase plate usage. journals.iucr.org/m/issues/202...

The concept that STEM is reciprocal to TEM is easier to explain with a Nion Column

At one point, I even did electron microscopy in vacuum AND in air (we had an airSEM ... RIP).

Ha! just realized that not only and I bilingual in (transmission) electron microscopy (TEM/STEM), I'm also bilingual in TEMperatures (🤣🤣, RT and cryo), AND bilingual in scanning and transmission electron microscopy.

Our latest @biorxivpreprint.bsky.social: "Prion-like transmission of human tau strains in the mouse brain" 🥳 With Michel Goedert and Masato Hasegawa. www.biorxiv.org/content/10.6...

Now, even though I say funny things about STEM, I gotta tell you, it's is fun to do, beautiful to collect data in, and I love being able to be bilingual in electron microscopy 😝😝 (TEM and STEM).

Things I say when I'm explaining TEM vs STEM: well, you can think of STEM as reciprocal TEM (always makes people lol). And: oh yeah, because STEM folks don't call it beam, they call it probe, and they don't list the whole beam, just the angle, in mrad 😝

Took a little bit of franken-doing, but, I have two used but in very used condition racks in the old dishwasher. Not more rusted racks. There was blood shed (mine, ofc). But, I did it!

Don't get me wrong, I love biology. A lot. But sometimes I wonder, if I had believed in myself enough, if I couldn't cut it as a mechE. Not too long ago, one of our detectors was acting up. One of my colleagues and I decided to take it apart and check things out, see if anything obvious jumped out