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Corrie Detweiler

@csdetweiler.bsky.social

Microbiologist researching anti-infectives, Prof at University of Colorado, Editor in Chief of #MMBR (Microbiology and Molecular Biology Reviews), an American Society of Microbiology ‪(ASM‬; ‪@asm.org‬).

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Corrie Detweiler@csdetweiler.bsky.social · last yr.

Thoughtful questions. We microbiologists ARE ASM. @asm.org @vscooper.micropopbio.org @microgem.bsky.social @gilbertjacka.bsky.social @romneyintn.bsky.social @abaumler.bsky.social @blugenes.bsky.social @chicascientifica.bsky.social @ssclabquips.bsky.social @goodrumviruslab.bsky.social

Nagissa Mahmoudi@nagissa.bsky.social · last yr.

I've grown increasingly upset about ASM's actions and the way this situation may have unfolded. Whose idea was this? Was there a meeting with ASM leadership and they flagged webpages to be taken down? Did they vote on this? Was this done unilaterally by a single person? #MicroSky

Corrie Detweiler@csdetweiler.bsky.social · last yr.

ASM has begun to respond: asm.org/Press-Releas... We need to continue constructively criticizing but also supporting ASM and all other science-based institutions.

ASM Responds to Member Questions About Executive Orders

Our modified pages are back up or in the process of being restored. ASM has not retracted or altered any research articles, scientific papers or peer reviewed articles on our website.

asm.org

Jennifer Goff, PhD@jlgoff.bsky.social · last yr.

It has been brought to my attention that my article has been censored to exclude certain terms: asm.org/Articles/202... web.archive.org/web/20250114... #MicroSky

Corrie Detweiler@csdetweiler.bsky.social · 2y ago

Thank you, Vaughn. The importance of leadership at ASM grows by the minute. We are lucky to have Michele Swanson as our current President, Alex McAdam @amcadamclinmicro.bsky.social as President Elect, and you on board for July 2026. @asm.org

Vaughn Cooper@vscooper.micropopbio.org · 2y ago

I'm incredibly honored by this opportunity to serve as President-Elect of @asm.org starting this summer. Looking forward to working with the Board, ASM leadership ,and staff to help advance the microbial sciences. I'm also glad to share my Vision statement, please join us! asm.org/Press-Releas...

Corrie Detweiler@csdetweiler.bsky.social · 2y ago

NPPB bound in the channel of TolC, below, prevents export of, among other things, the RtxA1 toxin, a virulence factor that rapidly kills host cells.

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ASM@asm.org · 2y ago

The chloride channel blocker NPPB can potentiate the activity of antibiotics against the so-called flesh-eating bacterium Vibrio vulnificus by inhibiting TolCV1, a component of efflux pumps, which are critical for antibiotic resistance. #AACJournal: journals.asm.org/doi/10.1128/...

Heat plots of checkerboard assays of antibiotics in combination with NPPB against V. vulnificus. (A) Kanamycin, (B) tetracycline, (C) erythromycin, (D) ampicillin.
Corrie Detweiler@csdetweiler.bsky.social · 2y ago

Gene expression from the pLS20 conjugative plasmid is controlled by a mechanosensing signal transduction pathway responsive to flagella rotation, a strategy that may allow dissemination of the plasmid to remote destinations and infiltration of new niches.

Ákos T Kovács@evolvedbiofilm.bsky.social · 2y ago

Flagellar rotation facilitates the transfer of a bacterial conjugative plasmid @embojournal.bsky.social from Sigal Ben Yehuda www.embopress.org/doi/full/10....

Corrie Detweiler@csdetweiler.bsky.social · 2y ago

Aurodox is a Streptomyces metabolite (linear polyketide) that interferes with Gram-negative bacterial infections of host cells. Roe et al. show Aurodox could work by reducing transcription across phylogenetically distinct Type Three Secretion Systems in E. coli, Salmonella, Yersinia and Vibrio spp.

Professor Andrew J Roe@drandyjroe.bsky.social · 2y ago

New paper from the group. Very proud to share our recent work for the first time here on Bluesky- give me 50 likes and it’s a permanent move!🤣. doi.org/10.1098/rsob...

Cartoon showing how aurodox can inhibit multiple gram negative pathogens. Image by Iris Floria
Corrie Detweiler@csdetweiler.bsky.social · 2y ago

Bacterial rRNA modification profiles are rapidly altered in an antibiotic-specific manner. @evamarianovoa.bsky.social

ᐯIᑕTOᖇ ᑎIᘔET, ᗰᗪ@nizet.bsky.social · 2y ago

Impressive work from lab of @evamarianovoa.bsky.social Scalable and reproducible workflow of native RNA nanopore sequencing + NanoConsensus analysis finds significant rRNA modification changes in response to antibiotic stress—genuinely novel concept for AMR research www.nature.com/articles/s41...

Jeremy Berg@jeremymberg.bsky.social · 2y ago

I am taking care of our neighbor's cat for the holiday. Their door lock has been hard to open and wouldn't budge this morning. I remembered our mechanical engineer daughter's rules: If it is moving and is not supposed to: Duct tape If is supposed to move and isn't: WD40 Problem solved: Cat fed.