Join us at Institute of Biology Leiden (IBL) as an Assistant/Associate/Full Professor in Mechanisms of Disease Apply before 31st August, 2026: careers.universiteitleiden.nl/job/Assistan...

Our paper on how better amino acid substitution matrices trained on cleaned alignments improve gene tree inference, and on best practice for cleaning MSAs more broadly, is now out academic.oup.com/mbe/advance-.... New options in both IQTree and Muscle5. @phylowheeler.bsky.social

Improved gene tree inference from removing alignment errors both from focal genes and when training substitution models

Abstract. Multiple Sequence Alignment (MSA) is a key step in phylogenetic analysis and is prone to error. Unfortunately, algorithms that remove likely alig

academic.oup.com

Joanna Masel@joannamasel.bsky.social · 8mo ago

Sequence alignments are notoriously prone to error. Our latest preprint offers a new tool for filtering errors out, assesses it and other filtering tools, and recommends new best practice. www.biorxiv.org/content/10.6... @phylowheeler.bsky.social 1/10

It's out! Excited to present the Great Barrier Reef Microbial Genomes Database (GBR-MGD), a comprehensive DB of 1000s of high-quality prokaryote, virus, plasmid, and chromosome-level eukaryote MAGs using Nanopore long reads. Subthreads incoming. Please share widely. 🙂 www.nature.com/articles/s41...

The planktonic microbiome of the Great Barrier Reef - Nature

The Great Barrier Reef Microbial Genomes Database compiles prokaryotic, viral and eukaryotic genomes from seawater collected from the Great Barrier Reef, providing a rich resource for the study of mar...

nature.com

Starting with the DNA sequence of a #phage genome, #PholdAPhage will create a 3D reconstruction of the complete phage, almost like you did cryoEM on it! Check out Renee's awesome software github.com/reneegreen81... to assemble unknown phage particles one protein at a time

🚨 We're hiring! My new lab at EMBL Hamburg is looking for a Research Technician. I'm looking for someone excited by phages, metabolism, enzymes, structural biology and bacterial immunity—if you know the right person, please share this post!🧵⬇️ Apply here: embl.wd103.myworkdayjobs.com/en-US/EMBL/j...

Research Technician (Osterman Group – Metabolism-driven immunity)

EMBL Hamburg / CSSB The European Molecular Biology Laboratory (EMBL) is Europe’s flagship life sciences organization, with more than 110 independent research groups across Heidelberg, Hamburg, Grenobl...

embl.wd103.myworkdayjobs.com

Excited to share that I've been awarded a 5-year NIH MIRA (R35) from the National Institute of General Medical Sciences! The lab is growing! We're recruiting postdocs and research techs interested in microbial ecology, quantitative microscopy, microfluidics, and molecular biology. Please share!

Postdocs and early career folks - this is a truly wonderful opportunity to spend time in Berlin, gain time to think, and expand your network! call.wiko-berlin.de/procedure/65...

@breakliquid.bsky.social and I are delighted to say our OpenEVO preprint is finally live! An open source hand-made turbidostat that's modular, affordable, and made to be customized. Designed with love for the research community. Enjoy!!!💚 www.biorxiv.org/content/10.6...

OpenEvo: An Open-Source Platform for Automated Evolution and Analysis

Here we introduce OpenEvo, a fully open-source, low-cost turbidostat platform for automated continuous culture and directed evolution experiments. Existing tools are expensive, complex, or lack open-s...

biorxiv.org

My department @eth-dbiol.bsky.social at ETH Zurich is hiring for a tenured professor in mol cell bio and biochemistry (associate/full). The position is within the Institute of Biochemistry (www.bc.biol.ethz.ch) and it is fairly open within their scope of research. www.nature.com/naturecareer...

Professor of Molecular Cell Biology and Biochemistry - Zurich, Switzerland job with ETH Zurich | 12861386

The Department of Biology at ETH Zurich invites applications for the above-mentioned tenured professorship at the Institute of Biochemistry

nature.com

New study by Alexander Henoch (@ahenoch.bsky.social), a PhD student in our group @hifmb.de and @awi.de, shows what it takes to bring gene synteny into microbial pangenomes, and what we learn about the variability landscape of genomes when we do that. See the pre-print here: doi.org/10.64898/202...

Synteny-aware microbial pangenome graphs reveal blueprints of genomic variation https://www.biorxiv.org/content/10.64898/2026.07.03.736256v1

Ancestral genome reconstructions get noisier the deeper in time you go. The usual response: distrust them and joke about reading entrails. Ours is to train on the noise! The result is calibrated phenotype prediction back to the LBCA deep in the Archaean. New preprint www.biorxiv.org/content/10.6...

Models trained with noisy genomes extend bacterial phenotype prediction into deep time

Predicting phenotype from genotype in extant organisms is increasingly tractable through the accumulation of genome sequences and the development of machine-learning algorithms. Here we show that mach...

biorxiv.org

Membrane protein solubilization and structure determination using de novo–designed proteins | Science www.science.org/doi/10.1126/...

Membrane protein solubilization and structure determination using de novo–designed proteins

Developing therapies and vaccines against integral membrane proteins is hindered by their extensive hydrophobic surfaces, which complicate production and structural analysis. Here, we describe a gener...

science.org

Have ideas for your own, independent research program in Theoretical Biology? Then come and join us as a Group Leader at the @mpi-evolbio.bsky.social in Plön, Germany!

Group Leader in Theoretical Biology (m/f/d)

Experience in Theoretical Biology, Applied Mathematics, Theoretical Physics

mpg.de

Open postdoc position in my lab on HGT and interbacterial competition. We seek candidates with a PhD in microbiology (or related fields)+ strong 1st-author publications. Curious, highly motivated, and dedicated team players ready to contribute fully are encouraged to apply. Details: tiny.cc/cz01101

Open Positions

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tiny.cc

I'm happy to announce the release of GlobDB r232! This version contains 346,233 bacterial and archaeal genomes, based on 26 datasets. More info globdb.org 🦠🖥️🧬

I'm happy to announce the release of GlobDB r232! This version contains 346,233 bacterial and archaeal genomes, based on 26 datasets. More info globdb.org 🦠🖥️🧬

The lab has several new papers out led by fantastic postdocs, with important contributions from other lab members and collaborators. Each paper focuses on different aspects of Wolbachia spread and effects on hosts. The first paper was led by Dylan Shropshire and is now in Genetics.

If Waffle House doesn’t make this their new slogan, then capitalism has failed

Just to up this #microsky #microbiomesky #IDsky deadline extended until 1st of July 2026. Come and join us a a (senior) lecturer in microbiome sciences, an academic position in a collegiate school with great facilities and opportunities!

Dutchscientist (the real one)@dutchscientist.bsky.social · 2mo ago

jobs.surrey.ac.uk/vacancy.aspx... Our School of Veterinary Medicine is recruiting a (senior) lecturer in #Microbiome Sciences, deadline is 16th of June 2026. We want to expand our capabilities in the microbiome field, quite flexible on what will be investigated within #OneHealth #MicrobiomeSky 1/n

New paper alert!! We just discovered a new filament system that is widespread exclusively within CPR bacteria! www.biorxiv.org/content/10.6.... Short thread below. 🦠🔬🚀

A Novel Pilus System in Candidate Phyla Radiation Bacteria

The Candidate Phyla Radiation (CPR) represents a bacterial superphylum estimated to include between 15–50% of all bacterial species, yet CPR bacteria remain challenging to culture and have been primar...

biorxiv.org

I'm happy to share the first pre-print of out Lab! 🎉 Introducing ArchaeaHQ www.biorxiv.org/content/10.6... We curated 21,644 genomes across all 4 archaeal kingdoms to bridge the gap in public datasets for computational biology What is inside ArchaeaHQ... (1/2)

I'm looking for an enthusiastic student to join my team as a PhD candidate on archaeal genome evolution 🦠💻 Work in beautiful Utrecht, at @binfutrecht.bsky.social, an international group full of caring, amazing scientists, and with frequent cake breaks! www.uu.nl/en/organisat... Please share! 🙏

Sulfoquinovose degradation by cow rumen microbiota #microbiology #microbiota #rumen #MicroSky @isme-microbes.bsky.social doi.org/10.1093/isme...

Sulfoquinovose degradation by cow rumen microbiota

Abstract. Sulfoquinovose, a sulfonated sugar derived from the thylakoid membrane lipid sulfoquinovosyl diacylglycerol, is abundant in photosynthetic organi

doi.org

Folddisco is now published @natbiotech.nature.com. It’s a fast motif search for similar 3D DISCOntinuous residues like catalytic sites or zinc fingers across the entire protein universe. 📄 www.nature.com/articles/s41... 💾 folddisco.foldseek.com​​​​​​​​​​​​​​​​ 🌐 https://search.foldseek.com/folddisco

Structural motif search across the protein universe with Folddisco - Nature Biotechnology

Folddisco enables protein structural motif search in million scale databases.

nature.com

Martin Steinegger 🇺🇦@martinsteinegger.bsky.social · last yr.

Folddisco finds similar (dis)continuous 3D motifs in large protein structure databases. Its efficient index enables fast uncharacterized active site annotation, protein conformational state analysis and PPI interface comparison. 1/9🧶🧬 📄 www.biorxiv.org/content/10.1... 🌐 search.foldseek.com/folddisco

Thrilled to announce that the Department of Microbiology at the University of Washington, School of Medicine is hiring at the Assistant Professor level (tenure-track)! The Pacific Northwest is an awesome place to live and do science 🧪🦠. Join us! apply.interfolio.com/185622 Applications due 8/1.

Looking for a #postdoc outside the US, focusing on gut microbiome, AMR dynamics & phage-bacteria interactions. Bridging wet lab and computational approaches🦠👩‍💻. Hartmann Lab, Northwestern University, defending late 2026. Boosts appreciated 🙏🧫🧪 #microbiome #metagenomics #MicroSky

New preprint! Cell division has to happen at the right place but how Archaea pick that place is unknown. We now identified a three-protein system, Dip, that positions the divisome at midcell in H. volcanii and is broadly conserved across Archaea. A thread 🧵 www.biorxiv.org/content/10.6...

@bcoltman.bsky.social

Alvaro Sanchez@asanchezlab.bsky.social · 3mo ago

The version of record of our revised preprint is finally out today. In it, we introduce a fast and reliable methdology for the full factorial design of microbial communities, i.e. constructing every monoculture, pair, trio, four-member,... n-member co-culture of N strains. doi.org/10.7554/eLif...

If you are an #AssistantProfessor or #Postdoc and are interested in applying for a #Veni grant, join us for these events to hear from awardees and reviewers. We will have dedicated sessions for all domains of NWO and ZonMw.

APNet - Assistant Professor Network Netherlands@apnet.bsky.social · 3mo ago

🚨 𝐀𝐫𝐞 𝐲𝐨𝐮 𝐚𝐧 #𝐀𝐬𝐬𝐢𝐬𝐭𝐚𝐧𝐭𝐏𝐫𝐨𝐟𝐞𝐬𝐬𝐨𝐫 𝐨𝐫 #𝐏𝐨𝐬𝐭𝐝𝐨𝐜 𝐚𝐧𝐝 𝐚𝐫𝐞 𝐲𝐨𝐮 𝐬𝐭𝐫𝐮𝐠𝐠𝐥𝐢𝐧𝐠 𝐰𝐢𝐭𝐡 𝐲𝐨𝐮𝐫 𝐍𝐖𝐎 𝐕𝐞𝐧𝐢 𝐏𝐫𝐞-𝐩𝐫𝐨𝐩𝐨𝐬𝐚𝐥? Join APNet for an exclusive 1-hour session: "𝐇𝐨𝐰 𝐍𝐎𝐓 𝐭𝐨 𝐖𝐫𝐢𝐭𝐞 𝐚 𝐕𝐞𝐧𝐢 𝐏𝐫𝐞-𝐏𝐫𝐨𝐩𝐨𝐬𝐚𝐥." 👉 𝐑𝐞𝐠𝐢𝐬𝐭𝐞𝐫 𝐟𝐨𝐫 𝐭𝐡𝐞 𝐞𝐯𝐞𝐧𝐭 𝐡𝐞𝐫𝐞: docs.google.com/forms/d/e/1F... (1/5)