𝗜𝗦𝗡 𝗩𝗜𝗗𝗘𝗢 𝗔𝗕𝗦𝗧𝗥𝗔𝗖𝗧 𝗦𝗘𝗥𝗜𝗘𝗦: APOL1 genotype and HIV infection: 20 year outcomes for CKD, CVD and hypertension. 2025 from @kireports.bsky.social www.kireports.org/ar... #VideoAbstract by @drsumanbehera.bsky.social & @dakidneydoc.bsky.social
Srikanth Bathini
@dakidneydoc.bsky.social
Nephrologist by Profession|Humanist by Nature|Live and Let Live|KIMS Hospitals Hyderabad,India|ISN#SoMe|Visual Abstract Editor-ASN Journals|Mentor-NSMC,Glomcon
Friends ! Check this survey on Pregnancy AKI Available in 20 languages Do share in your groups qualtrics.kcl.ac.uk/jfe/form/SV_... @dramiliflores.bsky.social @hswapnil.medsky.social @divyaveerssneph.bsky.social @kajareeg.bsky.social @dakidneydoc.bsky.social
Hypoelectrolytemia. Low K, Mg Ca, Na and P. Did you have to use more than the conservative measures for management?
Sounds like pseudoobstruction... seen in patients with Ogilvie syndrome. Can also cause severe electrolyte dysfunction. But quite rare.. mostly diagnosed by GI before the nephrologists get to see them
A big thanks to @myadla.bsky.social @dramiliflores.bsky.social @dilushiwijay.bsky.social @kajareeg.bsky.social @theisn.org @nephroseeker.medsky.social Thanks to the wonderful #NephSky community for tuning in! #ECNeph
A glimpse at the causes of an Acquired Bartter Defect too! #ECNeph @myadla.bsky.social @dramiliflores.bsky.social @dilushiwijay.bsky.social @kajareeg.bsky.social @theisn.org @nephroseeker.medsky.social
❓ What is this Acute Pseudo colonic Obstruction (Ogilvie’s syndrome)? 👉 Several theories have been proposed @myadla.bsky.social @dramiliflores.bsky.social @dilushiwijay.bsky.social @kajareeg.bsky.social @theisn.org @nephroseeker.medsky.social #ECNeph
👉 In vitro studies suggest that colonic Maxi – K channels are upregulated 👉 These are the same channels upregulated in CKD, enhancing gut excretion of potassium 👉 In ESRD, the colonic excretion of Potassium is 3-fold that of normal individuals #ECNeph @myadla.bsky.social @dramiliflores.bsky.social
Here are some of the case reports describing hypokalemia in Ogilvie’s syndrome @myadla.bsky.social @dramiliflores.bsky.social @dilushiwijay.bsky.social @kajareeg.bsky.social @theisn.org @nephroseeker.medsky.social #ECNeph
Can there be any other cause for hypokalemia in this case? There are several case reports of Ogilvie’s syndrome being associated with severe hypokalemia @myadla.bsky.social @dramiliflores.bsky.social @dilushiwijay.bsky.social @kajareeg.bsky.social @theisn.org @nephroseeker.medsky.social #ECNeph
Here’s an infographic describing the various mechanisms of hypokalemia Highlighted in brown = Present in this case Shout out to @dana_m_larsen , my Nephrologist colleague from UCSF for the amazing infographic #ECNeph @myadla.bsky.social @dramiliflores.bsky.social @dilushiwijay.bsky.social
What do you do when there is a fluctuating acid base disorder in hypokalemia? Keep Calm … #ECNeph @myadla.bsky.social @dramiliflores.bsky.social @dilushiwijay.bsky.social @kajareeg.bsky.social @theisn.org @nephroseeker.medsky.social
🧠 worth considering — especially if we have renal potassium-wasting, in the set of GI loss #ECNeph
Here’s a review of the initial clinical course: Note that there was a fluctuating acid base balance -> look at the case summary #ECNeph @myadla.bsky.social @dramiliflores.bsky.social @dilushiwijay.bsky.social @kajareeg.bsky.social @theisn.org @nephroseeker.medsky.social
The patient was treated with 50 mg of Spironolactone and Oral Potassium of 70 mmol per day and maintained normokalemia and normal bowel movements. @myadla.bsky.social @dramiliflores.bsky.social @dilushiwijay.bsky.social @kajareeg.bsky.social @theisn.org @nephroseeker.medsky.social #ECNeph
Now that we know that there is a chloride, Potassium and Calcium loss disorder…. @myadla.bsky.social @dramiliflores.bsky.social @dilushiwijay.bsky.social @kajareeg.bsky.social @theisn.org @nephroseeker.medsky.social #ECNeph
28/n what next #ECNeph? Peel another banana? @dakidneydoc.bsky.social @dramiliflores.bsky.social @myadla.bsky.social @dilushiwijay.bsky.social
34/ 🧪 What nephron segment could be acting out? #ECNeph @dakidneydoc.bsky.social @dramiliflores.bsky.social @myadla.bsky.social @dilushiwijay.bsky.social
36/n What’s your working diagnosis now? Time to zoom in! #ECNeph @dakidneydoc.bsky.social @dramiliflores.bsky.social @myadla.bsky.social @dilushiwijay.bsky.social
33/n 📊 So… if it’s not the aldosterone, who’s stealing the K+? #ECNeph #MedSky #NephSky @dakidneydoc.bsky.social @dramiliflores.bsky.social @myadla.bsky.social @dilushiwijay.bsky.social
22/n 🧐 How would YOU approach this case? What’s the unifying diagnosis? What test or clue are we still missing? #ECNeph @dakidneydoc.bsky.social @dramiliflores.bsky.social @myadla.bsky.social @dilushiwijay.bsky.social
32/n 🕵️ What’s behind the potassium leak? need more lab rouns? #ECNeph #MedSky #NephSky @dakidneydoc.bsky.social @dramiliflores.bsky.social @myadla.bsky.social @dilushiwijay.bsky.social
26/n 🧪 88 mmol/day of urinary K+… Are the kidneys holding back? Clues are leaking! #ECNeph @dakidneydoc.bsky.social @dramiliflores.bsky.social @myadla.bsky.social @dilushiwijay.bsky.social
23/n 🕵️♂️ Ready to solve the mystery? #ECNeph #MedSky #NephSky @dakidneydoc.bsky.social @dramiliflores.bsky.social @myadla.bsky.social @dilushiwijay.bsky.social
Amazing picture Welcome @ferarceamare.bsky.social #ECNeph
24/n 🔄 The potassium pendulum swings again—what’s sabotaging K⁺ retention? #ECNeph #MedSky #NephSky @dakidneydoc.bsky.social @dramiliflores.bsky.social @myadla.bsky.social @dilushiwijay.bsky.social
25/🔬 ↓ K+, ↓ Mg2+ and alkalosis joins the plot 🧪 We’ve seen this trio before... but where? #ECNeph #MedSky #NephSky @dakidneydoc.bsky.social @dramiliflores.bsky.social @myadla.bsky.social @dilushiwijay.bsky.social
