🎊 New drug revolutionising the management of #obesity ✅ New kid on the block 👀 Check out the visual abstract of the #REMODEL trial #semaglutide @theisn.org #ISNWCN @dilushiwijay.bsky.social @nephroseeker.medsky.social @dramiliflores.bsky.social

ISNkidneycare@theisn.org · 5mo ago

"Mechanistic effects of Semaglutide on kidney disease in type 2 diabetes: The REMODEL trial" by Katherine Tuttle et al, was awarded with #ISNWCN Preserving Kidney Health: Top Scored Abstract. Visual abstract by Kajaree, available for download here: https://bit.ly/4rMB27f

Glad to have discussed the case for #ECNeph. Thank you all for your support and guidance! @myadla.bsky.social @dramiliflores.bsky.social @dilushiwijay.bsky.social @theisn.org 🙌

🚨 Cardiorenal Syndrome (CRS): A Deadly Duo 🚨 Did you know the heart & kidneys are so intertwined that dysfunction in one can wreak havoc on the other? Let's dive into CRS today. A lucid read for every nephrology & cardiology fellow 🫀🩺 #MedTwitter #ISNTweetorial

Hi this is Dilushi, joining a bit late! And lurking tonight #ECNeph

“Now we must… turn words into actions: We need steady investment, teamwork across sectors, and real action in every corner of the globe. This isn’t just about better kidney care -it’s .. making healthcare fairer & more accessible for everyone, especially in LMICs that need it most.” 👏🎉

ISNkidneycare@theisn.org · last yr.

🌍 History made! For the first time, kidney care is on the global health agenda. #WHA78 adopted a landmark resolution recognizing kidney health in the fight against #NCDs. 👏 Thanks to Guatemala and the global kidney community for making this possible! #KidneyHealthMatters

🌍 History made! For the first time, kidney care is on the global health agenda. #WHA78 adopted a landmark resolution recognizing kidney health in the fight against #NCDs. 👏 Thanks to Guatemala and the global kidney community for making this possible! #KidneyHealthMatters

longer discussion including MRAs and ASIs here www.nephjc.com/news/2024/10... #WorldHypertensionDay

Finerenone Finally Finishing off Spironolactone? — NephJC

A commentary putting the recent finerenone and spironolactone trials in perspective

nephjc.com

BP Targets: the @kdigo.org www.nephjc.com/news/kdigo-bp The ESPRIT trial discussion www.nephjc.com/news/esprit The BPROAD discussion www.nephjc.com/news/bproad #WorldHypertensionDay #120ForAll

The KDIGO 2021 BP Guidelines — NephJC

KDIGO; BP; blood pressure; guidelines; kidney; kidney disease; CKD; transplant; bp measurement; AOBP; ABPM; ACE inhibitors

nephjc.com

The @thelancet.com review on global BP control www.thelancet.com/journals/lan... Worsening BP control in Canada www.sciencedirect.com/science/arti... Improving BP control in US from @amjhypertension.bsky.social academic.oup.com/ajh/article/... #Hypertension #WorldHypertensionDay

Global and national high blood pressure burden and control

High blood pressure is a leading modifiable cause of premature death and one of WHO's global targets for the prevention of non-communicable diseases. Monitoring high blood pressure globally while unde...

thelancet.com

K issues #NephJC www.nephjc.com/news/salt-su... Podcast www.nephjc.com/freelyfilter... K switch mechanism pubmed.ncbi.nlm.nih.gov/38081406/ in @ajkd.bsky.social pubmed.ncbi.nlm.nih.gov/37772757/ from @amjhypertension.bsky.social journals.physiology.org/doi/full/10.... #WorldHypertensionDay

The Na-K Exchange Saves Lives — NephJC

This week, we will discuss the SSASS trial. in which a simple switch of table salt with a K-enriched salt works miracles. Is it about the sodium or the potassium?

nephjc.com

The ARNI data in CKD here pubmed.ncbi.nlm.nih.gov/30002098/ #WorldHypertensionDay

Effects of Sacubitril/Valsartan Versus Irbesartan in Patients With Chronic Kidney Disease - PubMed

URL: http://www.isrctn.com . Unique identifier: ISRCTN11958993.

pubmed.ncbi.nlm.nih.gov

#23 𝗦𝗔𝗩𝗘 𝗧𝗛𝗘 𝗗𝗔𝗧𝗘 for next Space #WorldHypertensionDay: "Hypertension and the Kidneys." @edgarvlermamd.bsky.social @hswapnil.medsky.social @myadla.bsky.social @dilushiwijay.bsky.social @ferarceamare.bsky.social 🗓️ May 22 🕑 3:00 pm CEST ⏰ Set your alarm here: twitter.com/i/spaces/1jM...

Great meeting with the @ISNEducation social media team; lots of exciting projects on the horizon! We're looking forward to what’s coming next, so stay tuned!

Guatemala's resolution on kidney health: a historic opportunity - The Lancet www.thelancet.com/journals/lan... Tonelli et al: "We call on all 193 UN Member States to bring about positive change by voting to adopt Guatemala's resolution on kidney health at the 78th WHA in May, 2025."

Guatemala's resolution on kidney health: a historic opportunity

Although much remains to be done, tremendous progress has been made on the prevention and control of chronic non-communicable diseases (NCDs), with slow but steady health gains achieved for millions o...

thelancet.com

#AcademicSky #AcademicPublishing #AcademicChatter

📅 Get ready for the next #NephJC on May 29 🧠💊 We’ll dive into: Lorundrostat for Uncontrolled Hypertension — efficacy, safety, and what it means for the future of BP management. ⏰ #NephSky #MedSKy @nejm.org www.nejm.org/doi/ful...

#NephJC One of my fave all time papers in this topic is a proof-of-concept DDAVP in CKD: reduces bleeding time consistently @nejm.org pubmed.ncbi.nlm.nih.gov/6401193/

Deamino-8-D-arginine vasopressin shortens the bleeding time in uremia - PubMed

In a randomized double-blind cross-over trial we gave either 1-deamino-8-D-arginine vasopressin or placebo to 12 patients with uremia, hemorrhagic tendencies, and prolonged bleeding times. After vasop...

pubmed.ncbi.nlm.nih.gov

Don´t forget to advocate the resolution led by Guatemala on #WHA78: 🌍 Chronic kidney disease affects over 850M We must shift from silent neglect to strategic action. Awareness, prevention, and equity in care are our next steps. #NephJC @theisn.org #NephSky #MedSky www.thelancet.com/jo...

One the one hand, low risk intervention. On the other hand, still unclear benefits. We doctors like to feel like we are doing something to prevent bad outcomes…but “don’t just do something, sit there” is also appropriate in many patients #NephJC

a man stands in front of a whiteboard with the word wait written on it

ALT: a man stands in front of a whiteboard with the word wait written on it

media.tenor.com

🩸Desmopressin appears safe, any serious risks? Hyponatremia, headaches, hemoglobin drop 🧪 We need stronger data on who, when, and how much. #NephJC

#NephJC pubmed.ncbi.nlm.nih.gov/7702050/

Defective platelet aggregation in uremia is transiently worsened by hemodialysis - PubMed

Bleeding is a prominent feature of uremia and remains a significant cause of morbidity in hemodialysis (HD)-dependent patients. To measure the impact of the HD procedure, we performed a prospective cr...

pubmed.ncbi.nlm.nih.gov

I do that too. If severe AKI or CKD stage 5 knocking the uremia door I lower my HD threshold. That’s an area where data are needed though #NephJC

#NephJC

Nephrology Journal Club@nephjc.bsky.social · last yr.

↗️ vWF & Factor VIII levels rose significantly at 2h post-dose ⏳ But effects faded by 4h Is this enough to help during biopsy, but after it? #NephJC

specific studies comparing the efficacy of different administration routes is limited in kidney biopsy, in some cases for hematological disorder better SC #NephJC

🧪 Two RCTs, one question… very different paths: 🔹 Same drug 🔹 Different patients 🔹 Different doses 🔹 Different needles 🔹 Different expectations Feeling any twist ahead? #NephJC

🩸Kidney biopsy is essential for diagnosis, but bleeding remains a key concern — especially in CKD, and when it comes to preventing bleeding? On 2019 @ajkd.bsky.social core curriculum left us without clear guidance. #NephJC

🎨Beautiful visual abstract by Divya Bajpai #NephJC http://www.nephjc.co...

Desmopressin for kidney biopsy - The Visual abstract — NephJC

Does desmopressin reduce the risjk of post kidney biopsy bleeding? Checkout the beautiful VA answering this practical question by NSMC faculty Dr Divya Bajpai.

nephjc.com

Hi this is Dilushi, nephrologist from Colombo! First time joining #nephJC on Bluesky! No COI

📖 This weekend don't miss our @kireports.bsky.social #ISNFridaySelection: Open-Label, Randomized, Controlled, Crossover Trial on the Effect of Dapagliflozin in Patients With ADPKD Receiving Tolvaptan www.kireports.org/ar...

Iptacopan reduces proteinuria and stabilizes kidney function in C3 glomerulopathy. 2025 from @kireports.bsky.social www.kireports.org/ar... #VideoAbstract by @dilushiwijay.bsky.social & @priti899.bsky.social