Danielle Beckman

@daniellebeckman.bsky.social

PharmD, MS in Biophysics, PhD in Biochemistry 🇧🇷 Rio 🇺🇸 Sacramento 🇩🇪 Munich International Society of Long COVID & Post-Acute Infection Syndromes: https://islc-pais.com/ daniellebeckman.com

"ICUs all over the country were empty." Tell that to the families who lost loved ones, to the exhausted healthcare workers who watched patients die day after day. Tell that to the cities forced to dig mass graves because morgues were overwhelmed. History doesn't change because someone rewrites it.

From NBC News in April 10, 2020

Video shows giant trench being dug on NYC's Hart Island to bury coronavirus victims
The public cemetery is now getting five times the usual number of unclaimed bodies every week.
Dr. Lucky Tran@luckytran.com · 3d ago

I worked for New York’s largest medical center at the start of the pandemic. There were morgue trucks on the streets. They set up emergency medical tents in Central Park. Healthcare worker colleagues died. It is horrific that RFK Jr is on national TV lying that ICUs were empty.

Progress happens when people work together. Honored to be part of the new International Society of Long COVID & Post-Acute Infection Syndromes (islc-pais.com). Together, we're advancing understanding, treatment, and prevention of post-infectious diseases through rigorous science. #LongCOVID #PAIS

Logo of the ISLC, International Society of Long Covid & Post-acute infection syndromes
Andrew Ewing@andrewewing11.bsky.social · 6d ago

The official website of The International Society of Long COVID & Post-Acute Infection Syndromes — a global coalition of clinicians, researchers and advocates advancing evidence-based care. islc-pais.com

One more nail in the coffin of the "it's just deconditioning" hypothesis. 60 days of strict bed rest ≠ #LongCOVID or #MECFS. Rob's group shows that while exercise capacity may be similarly reduced, the underlying skeletal muscle biology is VERY different. Time to move beyond outdated assumptions.

Nature Communications
Article in Press
Skeletal muscle properties in long COVID and ME/CFS differ from those induced by bed rest
Tom Kindlon@tomkindlon.bsky.social · last wk.

Rob Wüst, corresponding author of the new paper: "Skeletal muscle properties in long COVID and ME/CFS differ from those induced by bed rest" www.nature.com/articles/s41... Link to his full post www.linkedin.com/posts/rob-w%... #MEcfs #LongCovid


Rob Wüst

  • 2nd

Associate Professor | Vrije Universiteit Amsterdam | Physiology | Human Movement Sciences | Metabolism | Microscopy | Chronic Diseases 

4h • Edited • 

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I am incredibly proud to share our latest study, published today in Nature Communications, as a follow-up from our 2024 Nature Communications paper.
https://lnkd.in/dij5WTNk

People with long COVID and ME/CFS are often told that their reduced exercise capacity and muscle abnormalities are simply the result of physical inactivity or “deconditioning.” We tested this assumption by comparing patients with healthy individuals who underwent 60 days of strict bed rest.

Although prolonged bed rest had major effects on physical fitness and skeletal muscle (see also: https://lnkd.in/dhx8JNQi), these changes were distinctly different from those observed in long COVID and ME/CFS. Our main conclusion: physical inactivity alone cannot explain the reduced exercise capacity and skeletal muscle abnormalities in these diseases.
This is important because it shows why a simple “just exercise more” approach does not reflect the underlying biology, particularly for people who experience post-exertional malaise. We need to understand the disease-specific mechanisms and develop safe, tailored treatments.

🧠 What if #LongCovid is, in part, a disorder of dopamine? Our new commentary explores how disrupted dopamine signaling may help explain fatigue, brain fog, and autonomic dysfunction, and what this could mean for future therapies. Open access link: shorturl.at/vLAfU

Article at eBiomedicine: 
Dopaminergic vulnerability in long COVID: striatal PET imaging at the brain-body interface

Eric Guedja, Danielle Beckman
Chantzy@chantzy.bsky.social · 4w ago

"Our findings provide compelling evidence that long COVID involves the loss of dopamine-releasing neurons," says Dr. Jeffrey Meyer, senior scientist at the Brain Health Imaging Center, Canada Research Chair medicalxpress.com/news/2026-07...

Most people who develop #dementia don't have a family history of the disease. Interactions between vascular health, metabolism, environmental exposures, and *increasingly* pathogens also play a role. Brain aging starts decades before symptoms appear. 🧠 www.nature.com/articles/d41...

How to avoid dementia — what the science really says

Ambitious studies have been examining the protective effects of diet, exercise and socializing — with surprising results.

nature.com

Negative trials matter. This study successfully removed GPCR autoantibodies from #LongCOVID patients, but symptoms didn't improve. That challenges one autoimmune hypothesis, though not autoimmunity as a whole. Question: Does anyone know of other GPCR immunoadsorption studies underway?

Immunoadsorption Versus Sham Treatment for Post-COVID Syndrome: A Randomised Sham-Controlled Crossover Trial

Immunoadsorption was not effective in reducing symptom burden in post-Covid syndrome.

thelancet.com

Beautiful tiny nudibranchs are spectacular, shell-less marine sea slugs known for their cartoonish looks and incredible vibrant color. With over 3000 known species these ocean dwelling fashion icons come in staggering varieties frilly, fuzzy, and beautiful patterns and shapes

As #HPV vaccine coverage continues to rise, cervical cancer deaths among young women plummeted. In the most highly vaccinated cohorts, deaths fell to ZERO. Among unvaccinated women, mortality rates barely changed. Vaccines save lives. www.thelancet.com/journals/lan...

Cervical cancer mortality trends following HPV vaccination in England, 2001–24: an analysis of population-based mortality data
Prof Peter Hotez MD PhD DSc(hon)@peterhotezmdphd.bsky.social · 2mo ago

My interview today with @npr.org @hereandnow.bsky.social about exciting new data @thelancet.com showing we can stop cervical cancer deaths using the HPV vaccine but why in the Southern U.S. we’re needlessly condemning a generation of girls and women to cervical cancer www.wbur.org/hereandnow/2...