Darragh O'Brien
@darraghobrien.bsky.social
Translational Proteomics & Neurodegenerative Disease at the University of Oxford. Tauopathy & Dementia. Protein structural plasticity, modification, and clearance. Research Fellow of Green Templeton College.
The University of Gothenburg is recruiting a Postdoctoral Researcher to develop fluid biomarkers for Parkinson’s using ultrasensitive immunoassays and clinical data. Closing date: 23rd April www.dementiaresearcher.nihr.ac.uk/job/postdoct...
Postdocto: Fluid biomarkers for Parkinson´s disease
University of Gothenburg seeks a Postdoctoral Researcher to develop fluid biomarkers for Parkinson’s using ultrasensitive immunoassays and clinical datasets.
dementiaresearcher.nihr.ac.uk
Great start to the global AAIC Neuroscience Next 2026 Conference at the UK Hub in-person event in Manchester. #Lewybodydementia #NeuroscienceNext #AAIC #dementiaresearch #Manchester
How people with brain disorders reveal important insights into our selves www.waterstones.com/events/our-b...
🧠What an amazing day we had yesterday at the @alzheimersocirl.bsky.social & DRNI event "Brain Health and Dementia: Understanding and Connection"! 👏Thanks so much to all the wonderful attendees for their interest, engagement, and participation, and to all the fantastic speakers!
😱 Only ONE day left to submit your abstract to DRNI ECR Day! ➡️ To submit an abstract or to register to attend, go to: dementianetwork.ie/news-item/dr...
DRNI ECR Day 2026 | Dementia Research Network Ireland
dementianetwork.ie
Dementia Research Network Ireland@drni.bsky.social · 9mo ago✨DRNI's annual ECR Day is back! 🤝Join what is a great opportunity for ECRs to present their research & network with peers! 🗓️DRNI ECR Day 2026 takes place 09 April 2026, in @universityofgalway.bsky.social ℹ️ For info re abstract submission & to register, go to: forms.office.com/e/7y89Ywbuuh.
Congratulations to the University College London’s Selina Wray, Ph.D., recipient of the #AAICNeuro Excellence in Neuroscience Mentoring Award.
Research Assistant role at University of Oxford DPAG. Work with iPSC derived neurons and glia to study Parkinson’s molecular and cellular biology. Closing date: 16th March www.dementiaresearcher.nihr.ac.uk/job/research...
Research Assistant: Neuronal Cell Biologist in Parkinson’s
University of Oxford DPAG seeks Research Assistant to work on iPSC models and Parkinson’s cell biology in the Laboratory of Molecular Neurodegeneration.
dementiaresearcher.nihr.ac.uk
Are you a health or social care professional working with PSP or CBD? Our #free guides offer practical insights to help you provide the best care. Download and share with your colleagues to make a difference! 👉 ow.ly/WjWx50Y4W2a #PSP #CBD #Downloads #Guides
Fully funded PhD at @ukdri.ac.uk UCL, London, studying astrocyte microglia crosstalk and synaptic loss in Alzheimer disease. www.dementiaresearcher.nihr.ac.uk/job/phd-astr...
PhD: Astrocyte-Microglia Crosstalk in Alzheimer’s
Fully funded PhD at UK Dementia Research Institute UCL, London, studying astrocyte microglia crosstalk and synaptic loss in Alzheimer disease.
dementiaresearcher.nihr.ac.uk
Had a great time representing the Human Brain Proteome Project during the "Friends of HUPO" social at #HUPO2025 last night. If you want to get involved, or simply hear more about the initiative, please get in touch 🧠
Two Postdoctoral Researcher Positions at University of Oxford to study Alzheimer’s disease using AI and iPSC models in the Translational Neuroscience Group. Closing date: 6th November www.dementiaresearcher.nihr.ac.uk/job/postdoc-...
Postdoc Researcher: Modelling Alzheimer’s’ with iPSCs & AI Phenotyping
Two Postdoctoral Researchers at University of Oxford to study Alzheimer’s disease using AI and iPSC models in the Translational Neuroscience Group.
dementiaresearcher.nihr.ac.uk
NEW: We’re honoured to be ranked number one in the Times Higher Education World University Rankings for the tenth consecutive year. 👏
Many thanks for the spotlight! "Trasna na dTonnta" (Across the Waves) is a great initiative from @drni.bsky.social for the Irish dementia research diaspora – a global community linking Irish dementia researchers on the island of Ireland to those undertaking research abroad #brainwaves 🧠🌊
Dementia Research Network Ireland@drni.bsky.social · 12mo ago🔦DRNI's Trasna na dTonnta has set its spotlight on @darraghobrien.bsky.social , neuroscientist at @ox.ac.uk! ➡️To learn more about Darragh's work in translational proteomics & neurodegenerative disease, & about Trasna na dTonnta, go to: dementianetwork.ie/trasna-na-dt...
University of Oxford seeks Research Associate to study extracellular vesicles and biomarkers in Parkinson’s disease using blood samples and iPSC based models. Closing date: 3rd October www.dementiaresearcher.nihr.ac.uk/job/research...
Research Associate: Extracellular Vesicle Biomarkers
University of Oxford seeks Research Associate to study extracellular vesicles and biomarkers in Parkinson’s disease using blood samples and iPSC based models.
dementiaresearcher.nihr.ac.uk
Excited contribute to this year’s lunch hour lecture program! It’s a free event and accessible to a non-specialist audience so please come and join me :)
UCL Faculty of Brain Sciences@uclbrainscience.bsky.social · last yr.🧠 What if we could watch dementia unfold in a dish—and stop it before it starts? Join Prof @selinawray.bsky.social (@uclqsion.bsky.social) on 18 Sept for a free @UCL Lunch Hour Lecture exploring the future of dementia research. 📅 1–2pm | 💻 Online 🔗 www.ucl.ac.uk/events/event...
ICYMI: New online! Trans-synaptic tau propagation in progressive supranuclear palsy
Trans-synaptic tau propagation in progressive supranuclear palsy
Nature Reviews Neurology, Published online: 05 August 2025; doi:10.1038/s41582-025-01129-zNew evidence supports trans-synaptic propagation of tau pathology in the neurodegenerative disease progressive supranuclear palsy.
bit.ly
Blood Biomarkers: Testing for Alzheimer’s Disease Professor Jonathan Schott @jmschott.bsky.social (UCL) explains how blood tests are reshaping Alzheimer’s diagnosis. Clear, current and clinically relevant. Recorded at the Wessex Dementia Research Conference youtu.be/3fLl1Mzwbsk
Blood Biomarkers & Testing for Alzheimer’s Disease
YouTube video by Dementia Researcher
youtu.be
A great story to be part of! Kudos to Mária, Anna, Anne, Sally and all of the team🧠
Tracking tau and cellular responses in human iPSC-microglia from uptake to seedable secretion in extracellular vesicles
The templated spread of tau aggregates in tauopathies has been attributed to neuron-to- neuron spread, but microglia have also been implicated through mouse studies. Here we examine in detail the upta...
biorxiv.org
Encaenia 2025 @ox.ac.uk with my 🧠 buddy @stephfowler.bsky.social. It was great to see fellow Enniscorthy native Colm Tóibín receive the honorary degree of Doctor of Letters for his contribution to literature and journalism 💜💛
Fantastic start to the day here at the 3rd "Human Proteome and Health" Symposium at Rhodes House where Dr Katerina Gospodinova from the ARUK-ODDI and @cmd.ox.ac.uk discussed proteomic profiling of the #matrisome for use a novel therapeutic modality in #Alzheimers Disease 🧠 @arukthamesv.bsky.social
Our review is out now in Molecular & Cellular Proteomics! We discuss the latest advances in #HDX mass spectrometry to aid neurotherapeutic design & development in #Alzheimers, #Parkinsons and #ALS, providing molecular insights into protein aggregation pathways and therapeutic antibodies 🧠
Driving Therapeutic Innovation in Neurodegenerative Disease with Hydrogen Deuterium eXchange Mass Spectrometry
Human neurodegenerative conditions such as Parkinson’s and Alzheimer’s Disease are characterized by the formation and deposition of toxic protein species which exacerbate neuronal dysfunction, impacti...
mcponline.org
External link live! Please share widely :-) WE ARE RECRUITING! 🥳 Are you an epidemiologist with strong quantitative skills and an interest in contributing to exciting research into the genetic architecture of vascular dementia? Come join our friendly and productive team at UCL! shorturl.at/aZ5Ua
Very pleased to share our review in @molneurodegen.bsky.social, assessing evidence for #ExtracellularVesicle associated #TDP43. We highlight knowledge gaps relating to its biomarker usage and possible involvement in seeding of templated aggregation in #ALS, #FTD and #LATE. doi.org/10.1186/s130...
Extracellular vesicles in TDP-43 proteinopathies: pathogenesis and biomarker potential - Molecular Neurodegeneration
Extracellular vesicles (EVs) are membrane-enclosed nanoparticles released by most cell types, and from multiple sub-cellular compartments. They carry a range of cargo biomolecules, including protein a...
doi.org
Could blood tests reduce diagnostic delays for dementia? Experts weigh in on our podcast – don’t miss this timely discussion with @ajh1269.bsky.social @ukdri.ac.uk Dr Mark Roskey from Quanterix and Dr Jay Amin, University of Southampton
Dementia Researcher: Clinical opportunity for Blood-based Biomarkers
In this episode of the Dementia Researcher podcast, host Dr Amanda Heslegrave leads an insightful discussion on one of the most promising developments in dementia diagnostics: blood-based biomarker...
pod.fo
Keeping up with the literature is essential. But so is devoting time to developing your own scientific ideas, writes Sheena Josselyn. #neuroskyence www.thetransmitter.org/craft-and-ca...
On the importance of reading (just not too much)
The real fun of being a neuroscientist, and maybe the key to asking and answering new questions, is to think big and take intellectual risks.
thetransmitter.org
🚨MRC Research Fellow Vacancy: Studying microglial ageing utilising iPSC-based cell biology, screening, biochemistry, genomics, imaging & bioinformatics @dervissalih1.bsky.social, UK DRI at UCL 🗓️ Closing 26 June 👉 www.ucl.ac.uk/work-at-ucl/...
UCL – University College London
UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).
ucl.ac.uk
