Latest work from our group on powdery mildew susceptibility is finally out! We show that host RALF signalling, cell wall organization, and apoplastic pH regulation are required for successful fungal colonization. Surprisingly, the function of RALFs is only partly dependent on FERONIA. #TRR356

New Phytologist@newphyt.bsky.social · 2mo ago

RALFs, likely combining cell wall and signalling functions, support powdery mildew infection of #Arabidopsis 📖 nph.onlinelibrary.wiley.com/doi/10.1111/... by Leicher et al. @WileyPlantSci #PlantScience

RALFs, likely combining cell wall and signalling functions, support powdery mildew infection of #Arabidopsis 📖 nph.onlinelibrary.wiley.com/doi/10.1111/... by Leicher et al. @WileyPlantSci #PlantScience

1/23 New preprint! Been thinking about the origin of cellular life. Specifically, how protocells (or *any* compartments) just aren't enough to support the evolution of increasingly complex cells. You gotta de-Darwinize the parts! The ribosome/genome do this. www.biorxiv.org/content/10.6...

Born from the collaborative spirit of #TRR356, I’m excited to share my first first-author project! 🪴🦠 What started as a side project with @kbuhrman.bsky.social led us to discover that KAR/KL and SL signalling fine-tune the strength and timing of plant defense responses in a conserved manner!

bioRxiv Plant Bio@biorxiv-plants.bsky.social · 3mo ago

Karrikin and strigolactone signalling affect pattern-triggered immunity and resistance to specific pathogens https://www.biorxiv.org/content/10.64898/2026.05.05.722863v1

Thrilled to see my main PhD project finally online @MolCell !! 🥳🌱🧬 If you want to know how the plant proteasome activators are sorted in a proteasome-dependent manner and how they coordinate transcriptional response during proteotoxic stress, please have a read ! 🤓 www.cell.com/molecular-ce...

Proteotoxic stress response is governed by ER-associated sorting of proteasome transcriptional activators

Langin et al. find that ER-associated sorting (ERAS) directs NAC53/78 turnover and activation to couple proteasome induction with repression of photosynthesis genes, linking proteostasis to energy met...

cell.com

Thrilled to introduce our next act 🎭 in @cp-molcell.bsky.social sciencedirect.com/science/arti... led by @glangin.bsky.social We uncover how proteotoxic stress is integrated across compartments, controlling proteasome activation ⚖️ vs photosynthesis repression 🌱 🧵(1/6) #proteostasis

Preprint alert 🚨 (1/10) 🧵 𝘈𝘶𝘵𝘰𝘱𝘩𝘢𝘨𝘺 𝘪𝘴 𝘢 𝘱𝘢𝘳𝘢𝘥𝘰𝘹 𝘪𝘯 𝘱𝘭𝘢𝘯𝘵 𝘪𝘮𝘮𝘶𝘯𝘪𝘵𝘺: It can promote resistance, susceptibility, or restrict cell death 🤯 So what is its actual role? We show it acts as a spatial organizer of immunity across cell types 🌱🦠 #proteostasis www.biorxiv.org/content/10.6...

Sebastian Schade from the Ulm University on Regulation of Powdery Mildew Susceptibility by CrRLK1L-RALF modules #MBP2026

New Preprint: Plasma membrane nanoscale dynamics of Arabidopsis leucine-rich repeat receptor kinase complexes (2026) https://www.tsl.ac.uk/publications/164874

bioRxiv: Plasma membrane nanoscale dynamics of Arabidopsis leucine-rich repeat receptor kinase complexes (2026)

Plasma membrane-localized receptors operate as dynamic signaling complexes and integrative networks, yet the spatial and temporal regulation of these interactions remain largely unknown. Here, by analyzing the components of a minimal Arabidopsis leucine-rich repeat receptor kinase network, we describe the differential diffusion and organization of receptor complex components and unveil the nanoscale spatial and temporal logic underlying the formation of receptor kinase complexes. The ligand-binding receptors FLS2 and BRI1, and the accessory receptor BIR3, are organized in plasma membrane nanodomains, within which the co-receptor BAK1 diffuses and is spatially arrested upon ligand perception. BAK1 spatial arrest relies on extracellular domain (ECD)-ECD interactions but does not require receptor complex activation. Mathematical modelling, single molecule imaging and bio-assays infer that accessory receptors maintain a dynamic pool of co-receptors in the vicinity of ligand-binding receptors to promote ligand-induced complex formation and signaling. We propose that ligand-induced receptor kinase complex formation is a deterministic process defined by the relative nanoscale spatial positioning of individual signaling and regulatory components.

doi.org

Want to image apoplastic pH in plants? 🔬 Two new papers from our team offer a full workflow plus open access analysis tools. Congrats to @aroessling.bsky.social, Niklas Mayle and @lguerard.bsky.social Nature Protocols: rdcu.be/e7R2E BMC Methods: lnkd.in/dctpWJ3X Happy Imaging!

An ancient alkalinization factor informs Arabidopsis root development https://www.biorxiv.org/content/10.64898/2025.12.22.695669v1

Membrane-binding domains define REMORIN phylogeny and provide a predicted structural basis for distinctive membrane nano-environments https://www.biorxiv.org/content/10.64898/2025.12.22.695504v1

Manipulation of REMORIN gene dosage affects salt signaling and tolerance in Arabidopsis thaliana https://www.biorxiv.org/content/10.64898/2025.12.22.695520v1

Our Mini-review is out now! Here we collect recent findings of RALF peptide functions, adress their (potential) roles in plant-microbe interactions and discuss the resulting emerging questions. Pls share! dx.plos.org/10.1371/jour...

The interplay of RALF structural and signaling functions in plant-microbe interactions

Rapid alkalinization factor (RALF) peptides are important signaling molecules binding to Catharanthus roseus receptor-like kinase 1-like (CrRLK1L)—LORELEI/LORELEI-like GPI-anchored protein complexes t...

dx.plos.org

Very excited to share that our paper "A RALF-brassinosteorid signaling circuit regulates Arabidopsis hypocotyl cell shape" is now published in @currentbiology.bsky.social ! Enjoy reading it!! www.sciencedirect.com/science/arti...

Very excited to share that our paper "A RALF-brassinosteorid signaling circuit regulates Arabidopsis hypocotyl cell shape" is now published in @currentbiology.bsky.social ! Enjoy reading it!! www.sciencedirect.com/science/arti...

A RALF-brassinosteroid signaling circuit regulates Arabidopsis hypocotyl cell shape doi.org/10.1016/j.cu...

Cell wall integrity and elicitor peptide signaling modulate antimicrobial defense in Arabidopsis via jasmonic acid https://www.biorxiv.org/content/10.1101/2025.09.09.675042v1