@dcheung26.bsky.social

4 year Wellcome trust funded PhD student at the University of Dundee. My research aims to understand the role and regulation of cholesterol metabolism in B cells.

I’m delighted to announce that my first paper has been published in eLIFE! In this paper, we explore how B cells alter their metabolism to fuel changes in cell growth and proliferation following stimulation with the toll-like receptor 4 (TLR4) ligand lipopolysaccharide.

Lipopolysaccharide stimulates dynamic changes in B cell metabolism to promote proliferation

B cell activation and antibody class switching requires coordinated metabolic rewiring, with essential roles for amino acid transport, cholesterol metabolism, and prenylation in driving proliferation ...

elifesciences.org