So fun to be part of such a rockstar panel with @rcbagot.bsky.social @mayoonthebrain.bsky.social and Friede Holze. If you look carefully you can see @deffinger.bsky.social 👀 whose beautiful work is now in press at Nature Communications 🧠

Liisa Galea@liisagalea.bsky.social · 3mo ago

up next with Sex-specific effects of psilocybin ? @melissaherman.bsky.social the imp of preclinical work because no expectation bias exists! Melissa looks at PVT paraventricular nucleus of thalamus. In humans 5HT7 increases with psilocybin in animals? More cfos+ in PVT in females but not males

@deffinger.bsky.social at Lived Experience Panel @acnporg.bsky.social #ACNP2026: We should be going from consultation to co-production in the integration of lived experience in research 🧠🧪

Our first Deep Dive of 2026 covers a Perspective calling for recognizing & removing barriers faced by researchers with lived experience of mental illness or SUDs who work in our field. By @umarchatterjee.bsky.social @mayaschumer.bsky.social @deffinger.bsky.social & colleagues youtu.be/y5fymczeNFc

The central role of lived experience in mental health research

YouTube video by NPP - Digital Psychiatry and Neuroscience (DPN)

youtu.be

My TEDx talk is live! It blends my story—from TBI to addiction to neuroscience—with practical tools for stronger emotional control and brain optimization. I’d be grateful if you shared it. www.youtube.com/watch?v=08Lg...

Getting Unstuck: Moving Towards Better Mental Health | Dr. Devin Effinger | TEDxBoulder

YouTube video by TEDx Talks

youtube.com

A powerful DPN Perspective from @umarchatterjee.bsky.social, @mayaschumer.bsky.social, @deffinger.bsky.social, @viscidula.bsky.social, Noel Vest, Michael Cahill, Brandon Staglin, & @ericjnestler.bsky.social. DPN is grateful for the authors' dedication to writing this!

If anyone is looking for a roommate (or knows of someone) and has a room at the Atlantis for @acnporg.bsky.social please let me know!

@deffinger.bsky.social and @melissaherman.bsky.social argue that, though many human psychedelic clinical trials are underway, preclinical studies remain our best bet to answer fundamental questions about the neurobiology of psychedelics. #neuroskyence www.thetransmitter.org/psychedelics...

Why we need basic science to better understand the neurobiology of psychedelics

Despite the many psychedelics clinical trials underway, there is still much we don’t know about how these drugs work. Preclinical studies represent our best viable avenue to answer these lingering…

thetransmitter.org

We still don’t know if microdosing psychedelics is effective or a placebo, but is it safe? Could microdosing activate cardiac 5HT2B receptors and cause valvulopathy? New work online at pubs.acs.org/doi/pdf/10.1... from @deffinger.bsky.social suggests that - at least in mice - the answer is no. 1/

THRILLED to share @acnporg.bsky.social news x2! 1) Our study group “Centering Lived Experience in Psychiatric Neuroscience Research” @ericjnestler.bsky.social @mayaschumer.bsky.social @deffinger.bsky.social @viscidula.bsky.social @noelvest.bsky.social @cahill-lab.bsky.social=ACCEPTED! 🤩 #ACNP2026

@acnporg.bsky.social brought @umarchatterjee.bsky.social @deffinger.bsky.social & me together last year: After finding each other on X-as we are all public/open about our lived experience -we met+discussed the ideas for this Study Group! Looking forward to doing this work together@ #ACNP2026💥🧠❤️

Uma R. Chatterjee, M.S., MHPS@umarchatterjee.bsky.social · 12mo ago

THRILLED to share @acnporg.bsky.social news x2! 1) Our study group “Centering Lived Experience in Psychiatric Neuroscience Research” @ericjnestler.bsky.social @mayaschumer.bsky.social @deffinger.bsky.social @viscidula.bsky.social @noelvest.bsky.social @cahill-lab.bsky.social=ACCEPTED! 🤩 #ACNP2026

It’s wild how much change is possible in this life. From relearning to talk post-TBI, to full blown heroin addiction, to a life beyond anything I could have imagined. Im very fortunate to not only be alive, but to have been selected to speak at 2025 TEDxBoulder!

Everyone approves of the dinner to end the #GRCPsychedelics 🦞 @deffinger.bsky.social @jasteralaina.bsky.social @sequencemyneuro.bsky.social @veronicachelu.bsky.social and Erin Neyhart

The inaugural #GRCPsychedelics was a success! I am honored to have been one of a few chosen to receive a travel award and be able to share the stage with the leaders in the field. 🙏 to the organizers! @alexkwan.bsky.social @vyazovskiy.bsky.social @melissaherman.bsky.social @viditavaidya.bsky.social

It’s a common misconception that, for the person with a SUD, the substances are the problem. In my experience, the real problem was much deeper. Until I addressed the underlying causes/conditions, longterm sobriety was unattainable. Link in bio. #sober #sobriety #sobersky #recovery

Was on a podcast recently where I dive into the neuroscience of addiction, psychedelics, and healing—from both the science and my lived experience. Grateful for the chance to share my journey and the science behind what’s actually going on in the brain. Check it out: youtu.be/uNXrbEuturY

Neuroscience, Addiction, 12 Steps with Dr. Devin Effinger & Sarah Pritchard - PART 1

YouTube video by Impacting Recovery - Uncensored

youtu.be

People have warned about #psychedelics and 5-HT2B receptor activation for years — citing potential cardiotoxicity. But no one had tested it. Until now. We used echocardiography to assess cardiac risk after chronic LSD microdosing in mice. @sthom003.bsky.social www.biorxiv.org/content/10.1...

Assessing the potential cardiovascular risk of microdosing the psychedelic LSD in mice

Microdosing, the prolonged ingestion of psychedelics at sub-hallucinogenic doses, has gained popularity for its perceived cognitive and emotional benefits. Psychedelics have high affinity for 5-HT2B r...

biorxiv.org

Winter brain 2025 was a blast! Our panel on microdosing #psychedelics was the most attended session of the conference. We covered 4 distinct areas: anecdotal/lived experience, preclinical neuroscience, clinical, and cardiovascular risk. Most people stayed after for a great discussion. #WCBR2025

Are you @winter_brain ?? Come check out our panel this afternoon on microdosing #psychedelics. Including lived experience, preclinical effects, clinical effects, and my work utilizing rodent echocardiogram to assess potential cardiovascular risks. #WCBR2025 🍄 @sthom003.bsky.social

Just getting into Tahoe. Who’s at Winter Brain??

An amazing honor to give NIH’s WALS lecture today as the last speaker under the leadership of NIH Director Dr Monica Bertagnolli

MM@phdeez.bsky.social · 2y ago

when you get to host your bad ass brilliant ass PhD advisor @bita137.bsky.social as an invited speaker for the prestigious NIH Wednesday After Lecures Series 🤗🥰 grateful for our friendship that has developed after all these years 🙏🏽

Great PDA seminars today by @deffinger.bsky.social and Jill King 🐭💊🧠

The Senate Committee on Health, Education, Labor, and Pensions, led by Senator Bill Cassidy (R-LA) - a gastroenterologist with an MD from LSU, just released a report entitled NIH IN THE 21st CENTURY: ENSURING TRANSPARENCY AND AMERICAN BIOMEDICAL LEADERSHIP. Since he is the ranking Republican, 1/n

#ACNP2024 highlight... getting to see @deffinger.bsky.social and share his exciting data 🧠🧠🧠

On tonight: Given that classical #psychedelics are 5-HT2B agonists, there is concern of a potential cardiovascular risk with prolonged use. To resemble human context, we chronically administered 2 low doses of LSD and performed echocardiograms at baseline, 4-, and 8-weeks. #ACNP2024

More specifically, on Monday afternoon you do not want to miss #ACNP2024 ’s only panel dedicated to an oxymoron: non-psychedelic psychedelics! It will be a trip! Or not….

Tracy Bale@thebalelab.bsky.social · 2y ago

Onboard and headed to #ACNP2024 🧠 in Phoenix ☀️ with @sthom003.bsky.social @acnporg.bsky.social Program looks exciting with brand new session this year on #PromisingTargets in neuropharm 💊. See you there!

Hello @acnporg.bsky.social! I am a postdoc interested in the intersection of neurobiological effects of trauma and #psychedelic mechanism of action. 1st time here. I’ll be presenting data investigating the cardiovascular effects of chronic, low-dose LSD in mice Wed night! Let’s connect!

Neuropsychopharmacology@npp-journal.bsky.social · 2y ago

We are officially on the ground in Phoenix so it's time for the #ACNP2024 role call 📣 Introduce yourself, your science, tell us if you're a veteran or first-timer, promote your poster/talk/favorite social - whatever you want, this is your space to say it ⬇️

Our most recent episode featured @deffinger.bsky.social discussing threat processing, the amygdala + psychedelics Check it out here: www.psychedelicbrainscience.com/podcast/epis...

Podcast | Your Brain on Science

Psychedelic science podcast delving into past, present, and future findings in a fun and accessible way

psychedelicbrainscience.com

Our final episode in the #psychedelic circuitry series!! And maybe the year?? This episode dives into threat, amygdala, PVN + how psychedelics alter these responses in male and females animal models! Featuring @deffinger.bsky.social ! www.psychedelicbrainscience.com/podcast/epis...

Podcast | Your Brain on Science

Psychedelic science podcast delving into past, present, and future findings in a fun and accessible way

psychedelicbrainscience.com

Huberman: cold plunge promotes a massive release in dopamine Lay public: cold plunge makes you happier Scientists: peripheral dopamine doesn’t cross the blood brain barrier. 😂 🤦🏻‍♂️

Bita Moghaddam@bita137.bsky.social · 2y ago

This post has aged well as I hear that after the impending "NIH overhaul" you can buy supplements to optimize your dopamine in Building 1 raw milk shakes with "male hormone support stack mix" will be available in Building 10 cafeteria and no, you don't get a discount if you got a ND on your grant

Introductory post on here sharing my latest paper in Nature Comms where I investigated the effects of the psilocin, the psychoactive metabolite of psilocybin, on behavioral responding and reactivity within the paraventricular nucleus of the hypothalamus. #psychedelic www.nature.com/articles/s41...

Increased reactivity of the paraventricular nucleus of the hypothalamus and decreased threat responding in male rats following psilocin administration - Nature Communications

The neurobiological mechanisms underlying the fast acting and long-lasting effects of these drugs are not fully understood. Here authors show that the psychedelic psilocin increases reactivity in the ...

nature.com