How is proliferation modulated in regeneration for tissues to reach their right size? We found that, in zebrafish scales, proliferation is shut down by a moving front of osteoblast maturation. The front's dynamics scale with tissue size, ensuring proper osteoblast amplification. tinyurl.com/5e45twx3

A moving front of osteoblast maturation scales regenerating zebrafish bone

Successful regeneration recovers lost tissues to their original form. Here, we investigate how proliferation of bone-forming osteoblasts is timely regulated to control tissue size during zebrafish sca...

tinyurl.com

Charles Darwin comes back to life to wish Sir David Attenborough a happy 100th birthday. Our 3.5-min film from the LANE (University of Geneva) celebrates "the man who helped the world fall in love with nature". Happy #AttenboroughDay ! #bbc @biology-unige.bsky.social

An extraordinary guest to celebrate Sir David Attenborough

YouTube video by The LANE channel

youtu.be

Tristan Guyomar and I wrote a review on physical mechanisms coordinating regeneration - Featured: signalling/mechanical gradients, travelling waves and nematic fields - Dramatis personae: axolotls, hydra, planaria, spiny mice and zebrafish (ofc) with a jellyfish cameo tinyurl.com/3upzrdbs

Gradients, waves and nematics: quantitative perspectives on regeneration

Regeneration restores a damaged body part to its original size, shape and structure. Research over the last decades identified signaling pathways, cel…

tinyurl.com

The lab’s first pre-print! We investigated how growth-inducing Erk activity waves are regulated in regenerating zebrafish scales. We discovered that Erk waves are followed by waves of expression of their own inhibitors, as predicted by excitable waves theory. tinyurl.com/26r2cmpj

New work from @desimonelab.bsky.social lab 🌊🐟

bioRxiv Developmental Biology@biorxiv-devbio.bsky.social · 11mo ago

Transcriptional feedback of Erk signaling waves in zebrafish scale regeneration https://www.biorxiv.org/content/10.1101/2025.11.19.689292v1

We have moved to this new location as we prepare to launch a new edition of the Practical Course on Developmental Biology, Quintya-2025. This course began more than 25 years ago, and we are excited to bring together an excellent lineup of faculty and students for this latest edition

Dive into our latest findings on this powerful structure here: “The claustrum is critical for maintaining working memory” biorxiv.org/cgi/content/...

The claustrum is critical for maintaining working memory information

Working memory (WM) enables the mammalian brain to temporarily store and manipulate information, supporting cognitive tasks and communication processes. Rather than depending on a single specialized a...

biorxiv.org