The multifaceted effects of paternal environments on offspring🌈 Latest from the @jamiehackett.bsky.social lab @embl.org, out now @embojournal.org: @bbbranjan.bsky.social & @mdura.bsky.social quantitatively investigate the impact of paternal environments on early embryogenesis. A #sciart 🧵

❓Can a father’s environmental exposures before conception influence their offspring? We systematically tackled this - identifying effects of paternal age, environment and genetics on early embryos - as well as confounding influences www.embopress.org/doi/full/10....

Embryonic signatures of intergenerational epigenetic inheritance across paternal environments and genetic backgrounds | The EMBO Journal

imageimagePaternal environmental exposures have been linked with modulation of phenotype and disease risk in offspring via largely unclear mechanisms. This study employs in vitro fertilization and sin...

embopress.org

Postdoc positions in epigenetics! We have several opportunities to investigate big picture questions on (epi)genome function & mechanisms Based @embl.org near Rome (Italy), we offer full scientific support/facilities, training & funding. Also...☀️🏛️🍕🏖️ See👇or contact me for other options. Pls RS

Happy to share our preprint👇 Congrats and thanks to all the co-authors 🙏

Jamie Hackett@jamiehackett.bsky.social · 2y ago

📢 Preprint! How does the environment of a father before conception influence offspring? Even more, how do paternal genetics & ages interact with exposures to affect F1 outcome? We tested this systematically, with intriguing findings & some cautionary tales🧵... www.biorxiv.org/content/10.1...