#platelets keep surprise me @immunothrombosis.bsky.social as always great imaging #isth2025 and very interesting par1 signalling in lymphatic endothelial bed SOA7
Leo Nicolai
@immunothrombosis.bsky.social
Junior Research Group Leader @LMU Munich, interested in vascular biology with a focus on platelets and immunothrombosis
Online now: Yacine Boulaftali, Steffen Massberg and I summarized recent key insights into the role of platelets in vascular inflammation: journals.lww.com/co-hematolog...
Immune cells contribute to thrombosis in mouse models - but what about human disease? We used scRNA Sequencing, flow cytometry and histology to better understand immune cells in human stroke thrombi www.sciencedirect.com/science/arti... now online @cp-immunity.bsky.social
Immunothrombolytic monocyte-neutrophil axes dominate the single-cell landscape of human thrombosis and correlate with thrombus resolution
Thrombotic diseases remain the major cause of death and disability worldwide, and the contribution of inflammation is increasingly recognized. Thrombo…
sciencedirect.com
#TheMoreTheMerrier! Pekayvaz @immunothrombosis.bsky.social Stark &co show @cp-immunity.bsky.social that non-classical monocytes help to resolve thrombi by recruiting neutrophils that become thrombolytic following hypoxia-induced programs! www.sciencedirect.com/science/arti...
Immunothrombolytic monocyte-neutrophil axes dominate the single-cell landscape of human thrombosis and correlate with thrombus resolution
Thrombotic diseases remain the major cause of death and disability worldwide, and the contribution of inflammation is increasingly recognized. Thrombo…
sciencedirect.com
Very happy to contribute another @bloodjournal.bsky.social cover with our story on aging platelets: ashpublications.org/blood/articl... Thoughtful commentary by Laura Gutiérrez in the issue as well.
Aging platelets shift their hemostatic properties to inflammatory functions
Key PointsPlatelets change their phenotype as they age in circulation, skewing toward inflammatory function over time.Genetic models of increased platelet
ashpublications.org
1/x Online now: Our work on platelet aging and inflammation in @bloodjournal.bsky.social led by superstar PhD student Afra Anjum: ashpublications.org/blood/articl...
Arterial thrombosis - studying platelet recruitment at the single cell level in vivo
It was an immense pleasure to host our 2nd #immunothrombosis Symposium @LMU Munich together with Konstantin Stark. Talks and discussions were outstanding, and new ideas & perspectives made the meeting really special!
