What if cytokine therapies could be delivered only where they’re needed? Using targeted gene delivery to the lung, we show it’s possible to locally control inflammation and limit pathology—without systemic effects. New research from @labliston.bsky.social www.science.org/doi/10.1126/...

Gene delivery of immunomodulatory cytokines to the lung preserves respiratory function during inflammatory challenge

Altering the lung microenvironment with immunomodulatory cytokine gene therapy improves lung pathology.

science.org

Registration is now open for the Computational Biology Annual Symposium 🧬 📅 13 May 2026 📍 Centre for Mathematical Sciences We hope to see you there! Register: www.c2d3.cam.ac.uk/events/comp-... #ComputationalBiology #Bioinformatics #AcademicSky

Carl de Boer on understanding the evolution of gene regulatory complexity and its role in complex disease #MITS2026

⭐ Spotlight on: Ida Jobe Today, we are delighted to introduce Ida Jobe, a PhD student on the BBSRC Doctoral Training Programme, working in the Department of Pathology! Read Ida’s story: bio-cam-spotlight-on.my.canva.site/ida-jobe @campathology.bsky.social @queens.cam.ac.uk #PhD #Research

Our Neurospicy Science Hour is happening tomorrow at the Department of Pathology for a calm, curiosity-led science experience designed for wonderfully wired minds. Follow the link below to book the last few remaining tickets for 9-10am! 🧠✨ 👉 www.eventbrite.co.uk/e/send-sessi...

SEND Session at the Pathology Family Day

Join us for a fun and informative SEND Session at the Pathology Family Day!

eventbrite.co.uk

🚨 New paper from the lab! 🚀 We explore flexibility and modulation of IRES-dependent translation in enterovirus genomes through upstream ORFs. Many thanks to all co-authors from the @campathology.bsky.social, CIMR and Cambridge Stem Cell Institute! dx.plos.org/10.1371/jour...

Flexibility and modulation of translation initiation in enterovirus genomes

Author summary Enteroviruses cause over a billion infections annually, leading to serious conditions such as hand, foot, and mouth disease and viral meningitis. While these viruses are known to encode...

dx.plos.org

📢 Don’t miss the next Cancer Biology and Medicine talk tomorrow! Cancer virology Prof John Doorbar @campathology.bsky.social 📅 Thurs 12 February, 9:30-10:30 📍Theo Chalmers lecture theatre, School of Clinical Medicine All welcome! @cambridge-scm.bsky.social

Catz Fellow Prof. Adrian Liston (2023) & colleagues have uncovered major differences in one type of white blood cell in people living with #Alzheimers disease – new evidence about how this disease progresses & could be treated: www.caths.cam.ac.uk/... @labliston.bsky.social @campathology.bsky.social

AI uncovers immune defect in Alzheimer’s disease

An international team of scientists led by a St Catharine’s Fellow has successfully harnessed artificial intelligence (AI) to uncover a defect in the immune system of people living with Alzheimer’s disease (AD) – providing new evidence about how this poorly-understood disease progresses and how it could be treated.

caths.cam.ac.uk

A new study by @translatingrna.bsky.social shows that Toxoplasma gondii suppresses immune alarms within minutes—pure supervillain energy. Inspired a diary from the perspective of Betty's cat Eddie, who uses the same tactics at home. Science imitates fluff! 😼📘 bit.ly/4rJN1DS

New research shows Salmonella hacks host cells within minutes, using its injectisome to boost factors like EGR1 and silence immune alarms. A masterclass in microbial stealth—and a reminder of how quickly pathogens can rewrite the rules. 👉 bit.ly/4iwuPsS #salmonella #pathogens #immune

Leg day taught me that two people can follow the same workout and one still walks out like a newborn deer. Turns out cells do the same thing. Professor Betty Chung shows they get identical RNA instructions but perform wildly differently. Even biology skips leg day. 💪 bit.ly/48nYqAo

An exciting, extensive new study has identified a specific fault in the immune system of people with Alzheimer’s disease, pointing to a previously underexplored avenue for understanding – and potentially treating – the condition.❤️‍🩹 Read more: www.path.cam.ac.uk/news/new-stu...

Our new study on #systemsimmunology analysis of #Alzheimers patients is out now at @alzdemjournals.bsky.social! This is the culmination of a collaboration with Rik Vandenberghe, Stephanie Humblet-Baron and Lidia Yshii's labs at KU Leuven. 🧵1/8 alz-journals.onlinelibrary.wiley.com/doi/10.1002/...

A systems immunology analysis of Alzheimer's disease reveals an age‐ and environmental exposure‐independent disturbance in B cell maturation

INTRODUCTION Alzheimer's disease is a severe neurodegenerative disorder, with multifactorial mechanisms of disease development and progression. Evidence from genetic association studies, animal mode...

alz-journals.onlinelibrary.wiley.com

Applications are now open for the 2026 Experience Postgrad Life Sciences Programme! ➡️ Find out more and apply: www.exppg.lifesci.cam.ac.uk #SummerResearch #LifeSciences #CambridgeUniversity

Say hello to our wonderful Infection and Immunity Research Theme Leads! New Lead Nerea shares some thoughts on the plans for the Theme moving forward. #BiologicalSciences @cambiochem.bsky.social @camvetschool.bsky.social @campathology.bsky.social

📢 We are hiring! We have a fully funded 4-year PhD studentship to study how RNA viruses steal ribosomes and reprogram host translation, thanks to funding from @campathology.bsky.social and @wellcometrust.bsky.social! Come join us! Full details: www.path.cam.ac.uk/graduate/ful...

There is no credible evidence that vaccines disrupt tumour suppressors or drive any process that results in cancer, says @viropractor.bsky.social 👇👇👇 bit.ly/3KdGFuS

We are hiring! 🔭🔬 We would like to share a very exciting Job Opportunity at the Cambridge Institute for Medical Research at the Cambridge Biomedical Campus for a Research Assistant / Research Associate. (Fixed Term) For more information or to apply click here: www.cam.ac.uk/jobs/researc...

September is #ChildhoodCancerAwarenessMonth, so we caught up with @sdt36suzanne.bsky.social, Professor of Childhood Cancer Biology @campathology.bsky.social. She talks about her research into why children get cancer and how that question has taken her around the world.🔬 youtu.be/f2yxccFfBk8?...

Professor Suzanne Turner

Research Stories: Remarkable people, groundbreaking work, global impact. In this series, our researchers talk about their work and the difference it is making around the world, from tackling climate…

youtu.be

Dr Perla Pucci, paediatric cancer researcher at @campathology.bsky.social, talks about one of the benefits of Cambridge: specialising in niche, cutting edge research in your department while also benefiting from a variety of perspectives and experiences at College. youtu.be/GEUVGzqKGCM?...

Dr Perla Pucci

Research Stories: Remarkable people, groundbreaking work, global impact. In this series, our researchers talk about their work and the difference it is making around the world, from tackling climate…

youtu.be

A new protein-based tool - courtesy of @atomicvirology.bsky.social - is boosting the fight against Oropouche virus. Find out more ➡️https://bit.ly/45pjia2 #oropouchevirus #slothfever

Are “exosome facials” the future of beauty — or a dangerous trend? Researcher James Edgar warns on BBC Radio 4's Inside Health that unregulated exosome treatments marketed for anti-ageing and skin rejuvenation may pose serious health risks. 🔗 www.path.cam.ac.uk/news/are-aes... #exosomes

Turns out our “resident” immune cells are more like Airbnb guests than homeowners 🧳🧬 A new preprint by @labliston.bsky.social shows that lymphocytes check in and out of tissues much more frequently than previously thought—the gut and liver are the hotspots. 🧠🛏️🧪 doi.org/10.1101/2025...

Mums, a young survivor & researchers met in Cambridge to fight ALCL—a rare cancer. From grief to action, their bond is reshaping research & care. This is what global solidarity, love & science can do. 💜 ➡️ bit.ly/3U20MOo @sdt36suzanne.bsky.social #RareCancer #HopeInAction #PatientVoices

Got a transplant? It turns out that you might be able to tell beforehand if the COVID vaccine will work for you. Scientists used immune profiles + machine learning to figure it out. An excellent summary ➡️ bsky.app/profile/labl...

Adrian Liston@labliston.bsky.social · last yr.

We have a new paper out at npj Vaccines! The study tackles the problematic question of why #transplant patients responded so poorly to the #COVID #vaccine. While most people had great antibodies from a single dose, only half of patients responded after three! 🧵1/6 www.nature.com/articles/s41...

How does HPV turn from a silent infection into cervical cancer? New research by @konstanze1.bsky.social shows that gene deregulation—especially of E6 & E7—drives cancer risk in the cervix’s transformation zone. Full study: doi.org/10.3390/v170... #HPV #CervicalCancer

We have a new paper out at npj Vaccines! The study tackles the problematic question of why #transplant patients responded so poorly to the #COVID #vaccine. While most people had great antibodies from a single dose, only half of patients responded after three! 🧵1/6 www.nature.com/articles/s41...

Systems vaccinology identifies immunological correlates of SARS-CoV-2 vaccine response in solid organ transplant recipients - npj Vaccines

npj Vaccines - Systems vaccinology identifies immunological correlates of SARS-CoV-2 vaccine response in solid organ transplant recipients

nature.com

New from the Koronakis Lab: PAK proteins can still influence cell shape even when switched off. 🧬 Drug-inhibited PAKs altered actin structure via unexpected PIP3 buildup—changing how we think about targeted cancer therapies. ➡️ bit.ly/4nqgqk2 #CellBiology #CancerResearch

🔬👨‍👧 Can you be a full-time scientist and a fully present parent? @labliston.bsky.social says yes—and lives it. As an immunologist, author, and equal co-parent, he’s challenging old norms in academia and making space for caregiving in STEM. Read his story: www.mothersinscience.com/journeys/adr...

Adrian Liston — Mothers in Science

SciDad journey of Adrian Liston, PhD, Professor of pathology; father of one, and academic father. Adrian’s story offers a look into equal parenting as a guiding principle for navigating both scientifi...

mothersinscience.com

PaCIFiC Facility launch marks a milestone in Cryo-Imaging at Cambridge ➡️ www.path.cam.ac.uk/news/pacific...