www.nature.com/articles/s41...

The effect of cohesin mutations on HLA-class II expression in the myeloid leukemia of Down syndrome - Leukemia

Leukemia - The effect of cohesin mutations on HLA-class II expression in the myeloid leukemia of Down syndrome

nature.com

A great time at WIMM Day as always. Great to hear about exciting science. Congratulations to DPhil students from our lab: Alia for presenting her work, and Anna for getting an award for public engagement in research!

New paper from lab: many congratulations to Rebecca, Alia and Lucy who led this work. And thanks to all collaborators and funders. @paediatrics.ox.ac.uk @imm.ox.ac.uk @oxfordcancer.bsky.social ashpublications.org/blood/articl...

The fetal specific gene LIN28B is essential for human fetal B-lymphopoiesis and initiation of KMT2A::AFF1 infant leukemia

Key Points. LIN28B, a fetal specific oncogene, is necessary for fetal B lymphopoiesis and KMT2A::AFF1 initiation of infant B ALLLIN28B stabilizes key fetal

ashpublications.org

#ScientistSpotlight 🧪 This week we’re featuring Emily Neil, a Postdoctoral Research Associate at the #MRCWIMM Emily is working on a particularly aggressive and treatment resistant subtype of childhood B cell acute lymphoblastic leukaemia (B ALL), defined by the TCF3::HLF gene fusion.

This Sunday is #InternationalWomensDay 🧪 Each year we take our Women of WIMM group photo, celebrating women across our entire community, from research and technical teams to professional services. Here is to the women of #MRCWIMM. @rdm.ox.ac.uk @medsci.ox.ac.uk @ox.ac.uk

Oxford's cancer researchers showcased cutting-edge data science and collaboration at @cancerresearchuk.org 's 2026 Data-Driven Cancer Research Conference this week, reinforcing Oxford’s pivotal role in progressing CRUK’s research data strategy. 👏 www.cancer.ox.ac.uk/news/oxford-...

Oxford Cancer Research Leadership Highlighted at CRUK’s Data-Driven Cancer Research Conference

Oxford University cancer researchers showcased cutting-edge data science and collaboration at Cancer Research UK’s 2026 Data-Driven Cancer Research Conference, reinforcing Oxford’s pivotal role in pro...

cancer.ox.ac.uk

Great 3 days at the @cancerresearchuk.org Data conference in Edinburgh: lots of food for thought. Was good to see #CYP cancer data/AI being discussed.

Wonderful work @abattacks.bsky.social ! Great to see this out. Many congratulations!

Abs Khan@abattacks.bsky.social · 5mo ago

Another step on the journey towards building human bone marrow in vitro: doi.org/10.1016/j.st... When we published our first version a few years ago (doi.org/10.1158/2159...) the glaring gap was the lack of mature osteolineage (bone forming) cells, adipocytes, and lymphoid cells.

bloodpodcast.transistor.fm/episodes/147...

Blood Podcast | CAR-iNKT cell immunotherapy and Jagged2/Notch regulation of HSC

In this week's episode, Blood editor Dr. Laurie Sehn interviews authors Drs. Anastasios Karadimitris and Maria Carolina Florian on their papers published in Volume 147 Issue 2 of Blood. Dr. Karadim...

bloodpodcast.transistor.fm

Concluding our interviews for #InternationalDayofWomenAndGirlsInScience2026, hear from DPhil in Cancer Science alumna, Rebecca Ling, now a Clinical Postdoctoral Fellow in @paediatrics.ox.ac.uk ⬇️ @medsci.ox.ac.uk www.cancer.ox.ac.uk/news/interna...

#WorldCancerDay | When time matters, waiting is not an option. Researchers at #MRCWIMM have developed a readily available immunotherapy approach that showed promise against difficult to treat childhood #leukaemia in early stage #research. 🧪 #ChildhoodCancer #CancerResearch

New ‘off-the-shelf’ immunotherapy shows promise for treating high-risk childhood leukaemia

Scientists at the University of Oxford, together with colleagues at Imperial College London and the University of Glasgow, have developed a new type of immunotherapy that could improve outcomes for in...

imm.ox.ac.uk

#WorldCancerDay Discovery and early detection matter 🧪 Research at #MRCWIMM shows that platelets carry #DNA, offering new insights into cancer biology and early detection through fundamental science. #CancerResearch #EarlyDetection @bethpsaila.bsky.social @rdm.ox.ac.uk @ox.ac.uk @medsci.ox.ac.uk 🧬

Platelets shown to store DNA in study that could transform cancer screening

Study led by Psaila Group uncovers previously unknown function of platelets as DNA ‘vacuum cleaners’ in the blood, with profound implications for cancer diagnosis and prenatal screening.

imm.ox.ac.uk

Was wonderful to participate in this symposium. Thanks for the invitation.

St. Anna Children's Cancer Research Institute (CCRI)@stanna-ccri.bsky.social · 6mo ago

🗣️Bridging developmental biology and childhood cancer research: The St. Anna CCRI Symposium 2026 brought together researchers to discuss cell fate in cancer and development and spark new collaborations. 🔬Together, we advance pediatric cancer research. www.youtube.com/watch?v=szcT...

Well done Okan!

Rhys Morgan@rhysmorganlab.bsky.social · 6mo ago

Very pleased to share our latest pre-print which showcases the incredible hard work and skill of Dr Okan Sevim. Our continued exploration of β-catenin's contribution to the post transcriptional landscape of blood cells led us to a LIN28B interaction. 1/7 www.biorxiv.org/content/10.6...

Congratulations to the winners of our DPhil in Cancer Science Onco-Innovation Project Sandpit: Michael Bryan, Eva Hanlon, Raul Cioca, Aglaia Skolariki, Nicole Cianci, Roy Rosman Nathanson, Alexandra Petukhova-Greenstein, Anna Prazmo, and Dylan Muldoon! 👏

Winners of DPhil in Cancer Science Onco-Innovation Project Sandpit Announced

Congratulations to the following DPhil in Cancer Science students — Michael Bryan, Eva Hanlon, Raul Cioca, Aglaia Skolariki, Nicole Cianci, Roy Rosman Nathanson, Alexandra Petukhova-Greenstein, Anna…

cancer.ox.ac.uk

Many congratulations to Lauren Murphy!

Radcliffe Department of Medicine@rdm.ox.ac.uk · 7mo ago

Congratulations to the 2025 RDM Graduate Prize winner - Lauren Murphy 🎉 The annual RDM Graduate Prize is awarded to current or recently graduated students of RDM supervisors for exceptional achievement in their research. Read more about Lauren's work 👇 shorturl.at/QWaty @imm.ox.ac.uk

Out in print this week @bloodjournal.bsky.social . Very proud of this collaborative work with Prof Karadimitris @imperialimmuno.bsky.social. Thanks to @cancerresearchuk.org and CwC_UK for funding this work. #InfantALL @paediatrics.ox.ac.uk @imm.ox.ac.uk

Blood Journals Portfolio@bloodjournals.hematology.org · 7mo ago

Off-the-shelf bispecific CD133-CD19 CAR-iNKT cells eradicate CAR antigen–high and –low medullary and leptomeningeal KMT2Ar ALL. Read in Blood: buff.ly/HIlsUq7 #ALL #BloodJournal

Congratulations Arundhati on passing your DPhil viva with no corrections to your thesis 🎉🍾. So proud of you! Many thanks to examiners Profs Chakraverty and Vormoor. @oxfordcancer.bsky.social @paediatrics.ox.ac.uk @imm.ox.ac.uk

Merry Christmas and a Happy New Year from our lab! May 2026 bring everything you hope for!

New lab photo 2025-2026 😊

Great to see this paper out! Congratulations to first author Alastair Smith and to Tom Milne who led this study. @imm.ox.ac.uk

Blood Journals Portfolio@bloodjournals.hematology.org · 9mo ago

Individual leukemias can develop unique enhancer profiles even when initiating from the same starting material. buff.ly/Dqc9I4a #hemesky

Patient-specific enhancers in genetically uniform leukemias buff.ly/wU28vLW #hemesky

Happy Diwali from our lab!

Very proud of Rebecca for getting this CRISCANCER fellowship to continue her clinical academic career! These intermediate fellowships are so valuable for clinician scientists 🎉 @imm.ox.ac.uk @oxfordpaediatrics.bsky.social @oxfordcancer.bsky.social

Oxford Cancer Announces 2025 CRIS Cancer Clinical Career Fellows

Oxford Cancer, together with the CRIS Cancer Foundation, is delighted to announce the appointment of the 2025 CRIS Cancer Postdoctoral Clinical Fellows: Dr Rebecca Ling and Dr Casmir Turnquist. Both F...

cancer.ox.ac.uk

A news feature from @cancerresearchuk.org about our recent research to close #CCAM.

Making immunotherapy better for children with acute lymphoblastic leukaemia - Cancer Research UK - Cancer News

iNKT cell therapy could make it possible to stop hard-to-treat forms of leukaemia using donated immune cells.

news.cancerresearchuk.org

Read about our @cclguk.bsky.social @littleprincesses.bsky.social funded research published in @bloodjournals.hematology.org . Well done Joe Cross and Lucy Field. Many thanks to Tom Milne and other collaborators. @oxfordpaediatrics.bsky.social @imm.ox.ac.uk ashpublications.org/bloodadvance...

Join me in The Science of Childhood Cancer lecture series hosted by @StJudeResearch this Thursday, September 25 at 12 CT/1pm ET where I will be presenting Developmental origins of infant acute lymphoblastic leukaemia. Register to attend: ow.ly/yzf550T7Iv3

Had a wonderful time as always at CLRUK annual meeting. It was great fun organising it with Lisa Russell, Karen Keeshan and Bill Grey . Very proud of Lucy Hamer for an excellent talk! #CCAM #bloodcancerawarenessmonth

Well done to @emilysn1.bsky.social from our group @imm.ox.ac.uk @oxfordpaediatrics.bsky.social for this award from the Kaiya Foundation to study VHR childhood ALL. #CCAM #bloodcancerawareness month. x.com/ttvoxfordshi...

That's TV Oxfordshire on X: ""Over the next year the plan is to look more specifically at the molecular mechanisms that occur during the initiation of the leukaemia." That's TV spoke to Dr Emily Neil about the grant she has been awarded for her research into leukaemia. https://t.co/MBWB4UAm6K" / X

"Over the next year the plan is to look more specifically at the molecular mechanisms that occur during the initiation of the leukaemia." That's TV spoke to Dr Emily Neil about the grant she has been awarded for her research into leukaemia. https://t.co/MBWB4UAm6K

x.com

See you all in York tomorrow for our annual CLRUK meeting. We have some exciting talks from students and ECRs and a keynote from Prof @adelekfielding.bsky.social