We're off to a great start for our Trainee Day! Thanks to Dr. Patricia Hunt, Leah Payne, and Dr. Kyle Siemers for their fantastic and highly informative professional development talks!
Amy Inkster
@amy-inkster.bsky.social
Postdoc in the Cardenas lab @Stanford Epidemiology, PhD in Medical Genetics @UBC & @BCCHResearch in @robinson_lab. Epigenetics and early development.
Congrats to Iciar and Ella on their newly minted degrees! And great to have previous grad @amy-inkster.bsky.social back for support! What a team!
We’re excited to share a new review article from the Robinson lab: lessons learned from genomic and epigenomic studies of the placenta. Key highlights below! doi.org/10.1016/j.pl...
Feels like a strange time to be sharing research news, but the final manuscript from my PhD is now available online! In this article we explore the unique low-methylated state of the inactive X chromosome in the human placenta. doi.org/10.1186/s132...
The role of the maternal X chromosome in brain aging www.nature.com/articles/s41... www.nature.com/articles/d41... @nature.com
X chromosome passed from mother to daughter influences brain ageing
X-chromosome inactivation affects age-related decline in spatial memory.
nature.com
Cool work adding to our understanding of the unique DNAmethylation landscape in human trophoblast cells
Excited to share our most recent work in Cell Stem Cell, led by @georgiaplea.bsky.social, characterising determinants of DNA methylation patterning in human trophoblast stem cells! A great collaboration with @vpglab.bsky.social. tinyurl.com/93mchcd2 @loke-ctr.bsky.social @cam-repro.bsky.social
Another preprint from the lab! This time from Laiba, who did an independent study course in the lab, and our MSc student, Keaton. Here we use public data to show changes in immune cell composition over gestation and with preeclampsia.
Distinct DNA Methylation Signatures in Maternal Blood Reveal Unique Immune Cell Shifts in Preeclampsia and the Pregnancy-Postpartum Transition https://www.biorxiv.org/content/10.1101/2024.12.13.628167v1
For my colleagues in placental research, the November installment of the North American Placenta Lab Meeting is happening this Tuesday (Nov 19) at 9:00 am PST/12:00 pm EST over Zoom (mcmaster.zoom.us/j/96005378701). See details on our scheduled speakers below!