🧬 New strategy to fight #AML: A study led by @floriangrebien.bsky.social & team at Vetmeduni, @stanna-ccri.bsky.social & CeMM identified the protein SPOP as a direct regulator of the stability of NUP98 fusion oncoproteins, a potential target for new therapies. ➡️ bit.ly/3M2RfWz 📄 bit.ly/4omtZ3x

Big thanks to @floriangrebien.bsky.social for a fantastic seminar yesterday at @humantechnopole.bsky.social 🔬🧬 a masterclass in dissecting AML vulnerabilities with precision and creativity. We loved the science and the lunch chat too! 👏 #cancerbiology #AML #condensates

🔬Pleased to have contributed to this study led by the Max Planck Institute for Molecular Genetics, now in Nature. The Grebien Lab (@floriangrebien.bsky.social) at St. Anna CCRI participated in uncovering how the microenvironment of nuclear condensates influences cellular function. shorturl.at/CYJOR

The unique interior of nuclear condensates

molgen.mpg.de

Congratulations to CeMM Adjunct PI @floriangrebien.bsky.social & his lab on their contribution to this Nature publication in collaboration with the @molgen.mpg.de! 🎉 🔗 Read the paper: tinyurl.com/33r82nw2

St. Anna Children's Cancer Research Institute (CCRI)@stanna-ccri.bsky.social · last yr.

🔬Pleased to have contributed to this study led by the Max Planck Institute for Molecular Genetics, now in Nature. The Grebien Lab (@floriangrebien.bsky.social) at St. Anna CCRI participated in uncovering how the microenvironment of nuclear condensates influences cellular function. shorturl.at/CYJOR

💡Research team finds CDK12 is a key vulnerability in AML with NUP98 fusions. New hope for targeted therapies in resistant childhood leukemia. Study by Vetmeduni, St. Anna CCRI @floriangrebien.bsky.social & @cemm-vienna.bsky.social in Nature Communications >>> www.nature.com/articles/s41...

Transcriptional and epigenetic rewiring by the NUP98::KDM5A fusion oncoprotein directly activates CDK12 - Nature Communications

The epigenetic and transcriptional roles of Nucleoporin 98 (NUP98) fusion oncoproteins in driving pediatric acute myeloid leukemia (AML) remain to be explored. Here, the authors identify a core s...

nature.com

🔬 New @natcomms.nature.com study by CeMM Adjunct PI @floriangrebien.bsky.social's team at CeMM, Vetmeduni Vienna & @stanna-ccri.bsky.social‬ uncovers how NUP98::KDM5A drives #AML via epigenetic rewiring—identifying CDK12 as a druggable target. ➡️ More: bit.ly/3Hm6dVa ➡️ Paper: go.nature.com/3H8eCM3

New year - new goodbyes 👋 Thank you, SelinaTroester for being a role model #PhDstudent for so many others in the #grebienlab over the years. You will be missed! @VetmeduniVienna @stanna-ccri.bsky.social @CeMM

📣Funded #PhDposition! – Pls RT! Looking for a passionate PhD student to explore cellular crosstalk in #TumorMicroenvironment combining #organoids #scRNAseq &high-res imaging. Join us @VetmeduniVienna in a vibrant research environment! #CancerResearch #PhD 👉 euraxess.ec.europa.eu/jobs/302158

🚨🚨 #NewPhD Alert from the #grebienlab 🚨🚨 Ludovica Proietti defended her PhD with a fantastic performance 🥇🎯 Congratulations, Ludo! 🎉🍾 #proudpi @VetmeduniVienna @StAnna_CCRI @CeMM_News

With #ASH24 @ash-hematology.bsky.social just around the corner, it’s a good moment to publicize again this starter pack on Leukemia! Drop a message if you want to be included! go.bsky.app/EY3k2bE

Let's build a starter pack for childhood cancer research. Please send a message to be added! 🎗️ go.bsky.app/Tpd9QnM

There ist still time to register for the St. Anna CCRI Symposium #CancerEpigenetics and explore groundbreaking research with top experts! >>> ccri.at/st-anna-ccri... 🗓 January 24, 2025, 14:00-17:30 📍 Van Swieten Saal, Medical University of Vienna

St. Anna CCRI Symposium 2025 - St. Anna CCRI

We are excited to invite you to the St. Anna CCRI Symposium on Cancer Epigenetics, taking place on January 24th, 2025. As the only research institute in central Europe dedicated exclusively to childho...

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