Why chemotherapy harms your bone marrow and how the damage could be prevented: Research from OICR Investigator Dr. Anastasia Tikhonova shines a light on the biology behind bone and blood health complications that arise after treatment with chemotherapy. https://bit.ly/4zFhW7c #OICR #cancerresearch

🧬 ⭐ Exciting news in prostate cancer research! A new study co-led by Dr. Jüri Reimand at OICR and Joachim Weischenfeldt at the University of Copenhagen is shedding light on why some prostate cancers become aggressive and spread, while others remain slow-growing. https://bit.ly/3WtKZfE

Q&A with Dr. Isaac Harris: New OICR Investigator discusses coming home to Ontario, the link between antioxidants and cancer, and how he wants his research to help improve your diet. https://oicr.on.ca/qa-with-dr-isaac-harris/ #OICR | #cancerresearch | #antioxidants | #supplements

The Marathon Continues. The Government of Canada has announced $80M for the next phase of the Marathon of Hope Cancer Centres Network, catalyzing up tp $160M with matching funds. We’re getting closer to finishing what Terry started, but there’s more to do. The next phase starts today.

Today marks the beginning of a new era at OICR and for cancer research in Ontario as Dr. Aaron Schimmer steps into his role as the Institute's President and Scientific Director. We welcome Dr. Schimmer as he joins us in our work to accelerate cancer research in Ontario. https://bit.ly/4pT7Tb4

👩🏻‍💻 Read about how Mya Thompson is informing researcher training and data access procedures for the Ontario Hereditary Cancer Research Network as part of a unique summer internship https://bit.ly/4g4adZu #datagovernance | #indigenoushealth | #cancerresearch | #OICR | #hereditarycancers

Mya Thompson is helping shape the future of Indigenous data governance in cancer research - Ontario Institute for Cancer Research

As part of a unique summer internship, Thompson is informing researcher training and data access procedures for the Ontario Hereditary Cancer Research Network (OHCRN). With a lifelong interest in health sciences and a passion for promoting equity for In...

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3D ultrasound pioneer transforming cancer imaging around the world: Over two decades as Co-Director of OICR’s Imaging Program, Dr. Aaron Fenster has developed 3D ultrasound systems that are improving cancer diagnosis and treatment. https://bit.ly/3QYzxq7

Watch our latest "Ask a Cancer Researcher" video with Dr. Raymond Kim to find out how vaccines are being developed to prevent cancers in individuals living with Lynch syndrome, who are at a much greater risk of developing cancer. #OICR #cancerresearch #immunotherapy #cancervaccines #Lynchsyndrome

🔍 TMIST is one of the largest #breastcancer screening studies ever conducted and is working to find out if a newer 3D imaging technology outperforms standard #mammography. Read more about TMIST, 3D mammography and how Canadian researchers are playing a key role. 👉 https://bit.ly/4x6ubt4

Massive international clinical trial aims to answer a pivotal question in breast cancer screening - Ontario Institute for Cancer Research

TMIST, co-led by Canadian researchers, is working to determine whether a newer form of breast imaging can better detect aggressive breast cancers. The Tomosynthesis Mammographic Imaging Screening Trial (TMIST) is one of the largest breast cancer screeni...

oicr.on.ca

Dr. Aaron Schimmer to join OICR as President and Scientific Director: the Institute will welcome the internationally recognized clinician-scientist and research leader in August 2026. https://bit.ly/4wSFZin

⚡ Exciting breakthrough from OICR’s Drug Discovery team. In collaboration with @ucsanfrancisco.bsky.social, they have developed a new way to stop #HIV from replicating. This approach is unlike any existing therapy and could lead to a new class of antiviral medications. 🧪 https://bit.ly/4nHYYZ3

Self-Dimerization Induced Proximity Targeting Chimeras (SDIPTAC) Lead to DCAF1 Loss of Function and Inhibition of HIV Replication

DCAF1 is a donut shaped WD40 repeat protein and a substrate receptor of two distinct E3 ligases. In HIV-1 infection, the viral protein Vpr binds to the top surface of DCAF1, changes its substrate specificity to degrade human proteins involved in antivir...

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❇️ Our new CATALYST funding stream is supporting four studies to unlock insights from existing patient samples and data, maximizing past research to drive future breakthroughs into the detection, diagnosis and treatment of cancer. News release 👉 https://bit.ly/4flsNfJ #CancerResearch #OICR

OICR supports four new studies seeking cancer insights from existing patient samples and data - Ontario Institute for Cancer Research

CATALYST will speed progress toward better detection, diagnosis and treatment for patients. May 13, 2026, ONTARIO — Four new research studies funded by the Ontario Institute for Cancer Research (OICR)...

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Congratulations to NerView CEO and founder Mann Parikh and his team on winning FACIT’s Ernsting Entrepreneurship Award! Their promising technology can reduce the risk of nerve damage during surgery, helping patients better recover and maintain their quality of life. https://bit.ly/431H7mb

What's next in cancer research? We asked OICR's Dr. Michelle Brazas, and while the computational biologist is upbeat about the potential of AI, something else in cancer research has really grabbed her attention. Watch to find out more! 🎥❓👩‍🔬 #OICR #cancerresearch

🔔 Funding opportunity: OICR’s Clinical Translation program is inviting applications for Clinical Acceleration Team Awards to support multi‑centre clinical trials with molecular (minimal) residual disease as a component. 🗓️ Concept submissions due July 30, 2026 Learn more: oicr.on.ca/cata-rfa-2026/

👨‍⚕️🎥 We are back with another Ask A Cancer Researcher video! Watch Dr. Rob Grant explain how our DNA can be used to help choose the best treatment for a particular cancer. 🔎🧬 https://bit.ly/48gj4D9 #cancerresearch #pancreaticcancer #OICR #precisionmedicine #personalizedmedicine #BRCA

Can DNA testing help find the right cancer treatment?

YouTube video by Ontario Institute for Cancer Research - OICR

youtube.com

OICR is leading a new Ontario‑wide collaboration focused on advancing molecular residual disease research, using cutting‑edge blood tests to detect tiny traces of cancer that can remain after treatment and lead to recurrence. Read more 👉 https://bit.ly/4enOj2P #OICR #cancerresearch

Ontario collaboration aims to predict and prevent cancer recurrence before it happens - Ontario Institute for Cancer Research

OICR is leading a province-wide initiative to advance molecular residual disease (MRD) research and bring tests to patients. “Did you get it all?” It's often the first question a patient asks after cancer treatment, and one of the toughest questions for...

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In a recent interview with the @oicr.on.ca, Dr. Richard Kim discussed his research studying how rare genetic differences can impact the way patients with colorectal cancer respond to chemotherapy. To read the full interview, visit OICR’s website: oicr.on.ca/oicr-funded-...

OICR Drug Discovery is teaming up with Dr. Sheila Singh at McMaster University to develop a potentially game-changing treatment option for the most aggressive form of #medulloblastoma. This research could offer less toxic treatment to stop deadly childhood #braincancer https://bit.ly/4tGQL90

📣 News release: OICR's Cancer Therapeutics Innovation Pipeline is supporting four Ontario-based teams to develop the next generation of cancer therapies, designed to be more effective at destroying tumours, have reduced side effects and make cancer less likely to return. https://bit.ly/41vaywi

Newly funded projects to develop more effective drugs with fewer side effects for hard-to-treat cancers - Ontario Institute for Cancer Research

OICR funding is leveraging Ontario’s drug discovery expertise to answer the call for improved treatment options April 9, 2026 (Toronto) – Better cancer care depends on better treatment options. That’s...

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Dr. Glenn Bauman recently completed his time with OICR’s Clinical Translation program. In this Q&A he chats about his longtime involvement with OICR, its critical support of his practice-changing prostate cancer research and what’s new in cancer research in #LdnOnt. https://bit.ly/4kq2QvY

Q&A: Glenn Bauman on precision imaging, clinical translation, and cancer research in Ontario - Ontario Institute for Cancer Research

Dr. Glenn Bauman recently completed his time acting as an advisor within OICR’s Clinical Translation program. In this Q and A he chats about his longtime involvement with OICR, the Institute’s critica...

oicr.on.ca

OICR Investigator Dr. Brian Nieman is exploring how chemotherapy for the treatment of leukemia in children impacts brain development, which can put them at risk of long-term cognitive or behavioural problems. https://bit.ly/45IPZ27

📣 Tomorrow! 📣 Don’t miss this virtual event exploring how Network-funded health technology assessment projects are informing advances in precision oncology! 📆: Thursday, January 15, 2026 ⌚: 9am PT / 10am MT / 11am CT / 12pm ET / 1pm AT / 1:30pm NT 🔗 Register now: tinyurl.com/5dbdzsfb

New ICGC ARGO data dictionary, developed by OICR, to harmonize genomic and clinical data collected from around the world https://bit.ly/3NfvTGd #genomics #cancerresearch

Season’s greetings to everyone in the Ontario cancer research community and beyond. Thank you to all of those who worked with us and supported the Institute during our milestone 20th year and all those who have been a part of our success. Happy holidays and best wishes for a great year ahead!

Two decades ago, Ontario set out to create a world-class cancer research institute. Today, OICR is a cornerstone of Ontario’s life sciences ecosystem. Watch the video to see how far we’ve come, and where we’re headed next. https://oicr.on.ca/ #OICR20Years #cancerresearch

Aqsa, who lost her father and sister to cancer, works in clinical genome interpretation at OICR, preparing reports for patients. She enjoys this work, not just because she is helping patients but also that she able to "not let them be alone in their fears". https://bit.ly/4j0shUl #changedmylife

🧬 Protein that unties tangled DNA linked to hotspots of cancer mutations: Research from @reimand.bsky.social and his collaborators associated a chemotherapy-related cellular process with genetic mutations and used it to identify novel cancer driver alterations. https://bit.ly/4iMcV5B

Protein that unties tangled DNA linked to hotspots of cancer mutations - Ontario Institute for Cancer Research

Research from the Ontario Institute for Cancer Research associated a chemotherapy-related cellular process with genetic mutations and used it to identify novel cancer driver alterations. New research ...

oicr.on.ca

⚠️New study: we mapped DNA-binding of topoisomerase TOP2B in cancer, uncovering surprising hotspots of DNA damage. TOP2B, normally essential for DNA stress relief, can act as a double-edged sword. co-led by @LiisUuskula @ChristianLee, out now @natcomms.nature.com www.nature.com/articles/s41... [1/7]

Topoisomerase IIb binding delineates localized mutational processes and driver mutations in cancer genomes - Nature Communications

Topoisomerases resolve topological DNA stress via double-strand breaks and are established targets of cancer chemotherapies. Here, the authors link genomic binding of TOP2B with localized mutational p...

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We had the pleasure of hosting @torontomet.bsky.social students for a lab tour and panel discussion about careers in STEM. It was great to interact with students from TMU's biology, biomedical science, chemistry and medical physics programs and see their enthusiasm for research. Thanks for visiting!