Textbook: tracking position during navigation is primarily the job of the hippocampus. Recent findings suggest a more complicated story. Recording >20k neurons brainwide, we indeed find spatial representations in every region! With @kenneth-harris.bsky.social and @carandinilab.net

bioRxiv Neuroscience@biorxiv-neursci.bsky.social · 2w ago

Brainwide representation of navigation https://www.biorxiv.org/content/10.64898/2026.08.29.747979v1

1/7 🧠 My journey into development begins with this work and question: how does the brain's spatial navigation system develop? We found that the neural networks for spatial navigation (tori and rings) are preconfigured and only later anchor gradually to the world with experience! 🧵

Edvard I Moser@edvardmoser.bsky.social · 6mo ago

Is spatial navigation innate 🧠? Using #NeuroPixels we show that the #torus 🍩 underlying the #GridCell map exists already on day 10 in rats — before pups open eyes and ears and before they start upright walking. 🧵1:4 👇 www.biorxiv.org/content/10.6...

Latent geometry to describe neural variability with stable decoding! (use case in remapping) With the amazing @billpod.bsky.social Check it out! 🧠

Bill Podlaski@billpod.bsky.social · 9mo ago

I’m happy to share some recent work out in PLOS Computational Biology with @guille-martin.bsky.social and Christian Machens at @champalimaudr.bsky.social . We use neural coding and population geometry to study different perspectives on hippocampal remapping. journals.plos.org/ploscompbiol...

When neurons change, but behavior doesn’t: Excitability changes driving representational drift New preprint of work with Christian Machens: www.biorxiv.org/content/10.1...

Representational drift without synaptic plasticity

Neural computations support stable behavior despite relying on many dynamically changing biological processes. One such process is representational drift (RD), in which neurons' responses change over ...

biorxiv.org

Our preprint on tracking cells in 2p calcium imaging during development is now online at @elife.bsky.social ! Its cool that the reviews are open - now its revision time 🫡🫡🫡 doi.org/10.7554/eLif...

This is my first post here, and I'm happy to share some news. We've just launched megabouts.ai! 🐟📈 1/n

🔍 AI Researchers: Working on radically new AI frameworks or using unconventional math to rethink AI? 📢 Please send us names (incl. self-nominations!) for speakers at the New Math Approaches to AI meeting, Feb 3-4, 2025, at Champalimaud Foundation in Lisbon 🇵🇹. Let’s 🚀 push AI mathematics forward!

Made a generic feed/timeline with filters for AI safety, control, alignment and interpretability. Hope a community around this builds here. bsky.app/profile/did:...