Maria Ingaramo
@mariaingaramo.bsky.social
I'm a biochemist. I develop new fluorescent proteins and biosensors.
Proud of this work from David Wong-Campos (@wongcamposd.bsky.social), Pojeong Park, Byung Hun Lee (@bhlee1117.bsky.social), and team: www.nature.com/articles/s41...
Voltage dynamics of cortical dendrites in vivo - Nature Neuroscience
Simultaneous voltage imaging of soma and dendrites in layer 2/3 cortical neurons in live mice reveals rich dynamics of spike back-propagation, with amplitude shaped by spiking history, dendrite locati...
nature.com
We invented “triplet tumbling microscopy” (TTM) to track protein-protein interactions in living cells! Tag your protein with GFP and see it interact with *untagged* binding partners www.biorxiv.org/content/10.6...
MagLOV 2 plasmid is (finally!) available on Addgene 🎉🧲🧫 Any GFP capable imaging setup + benchtop power supply + off the shelf electromagnet is all you need to get started - let us know if you need help of course. www.addgene.org/252303/ @andrewgyork.bsky.social @mariaingaramo.bsky.social 🧪
Addgene: pGA-01-47
Plasmid pGA-01-47 from Dr. Harrison Steel's lab contains the insert MagLOV 2 and is published in Nature. 2026 Jan 21. doi: 10.1038/s41586-025-09971-3. This plasmid is available through Addgene.
addgene.org
Meet MagLuc: a magnetically-controlled luminescent protein. This is a foundational tool for remote control of biological processes, also known as "magnetogenetics". Can you tell when the magnetic field turns on and off? From @mariaingaramo.bsky.social and the team at @nonfictionlabs.bsky.social
Amazing work by Harrison and Gabi. They showed that MagLov proteins respond to radio frequencies, paving the way to precise magnetic field control of biology!
Gabriel Abrahams@gabriel-abrahams.bsky.social · 7mo agoOur research on magneto-sensitive fluorescent proteins and some of their applications has now been published! Huge thank you to the many many people involved in making this happen. 🧪 www.nature.com/articles/s41...
I'll be telling stories about science tonight in San Francisco. Come through! partiful.com/e/ldwWPLR2fO... The real draw is the crew hosting me, though. The local biotech hacker/maker/entrepreneur scene is PACKED with brilliant, inspiring folks. No slides, just stories.
RSVP to Lecture night with Andrew York | Partiful
Gather round the fire and make new friends! Andrew is a physicist at Calico and recently co-discovered magnetic responsivity in fluorescent proteins. It’s one of my favorite discoveries because it’s ...
partiful.com
For this #FluorescenceFriday I thought I'd repost my favorite blog post this year: MagLOV - magnetic control of a fluorescent protein! And now @mariaingaramo.bsky.social and @andrewgyork.bsky.social are here! Give them a follow and find out what cool things are next. blog.addgene.org/magnetic-con...
Magnetic Control of Proteins: More than a Dream
Magnetoresponsive proteins have seemed like a dream... but Andrew York's lab has developed and deposited one, opening the possibility of magnetoresponsive tools!
blog.addgene.org
Andrew G. York@andrewgyork.bsky.social · 2y agoMagLOV! MagLOV is a fluorescent protein you can "turn off" with a handheld magnet, engineered by @mariaingaramo.bsky.social. We think/hope we can use it to turn arbitrary proteins (including drugs!) on and off in opaque creatures (including humans!). bsky.app/profile/addg...